Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Katsumi Takaba"'
Publikováno v:
Journal of Pharmacological Sciences, Vol 124, Iss 2, Pp 201-207 (2014)
The mouse embryonic stem cell test (mEST) is used to assess the embryotoxicity of drug candidates by evaluating the effects on the cardiac differentiation of stem cells. However, thalidomide embryotoxicity has not yet been reported using the mEST. To
Externí odkaz:
https://doaj.org/article/97118b9707994356b8d386e4aa7b3fbe
Autor:
Hiroko Sanada, Jyoji Yamate, Kensuke Myojo, Minami Imaizumi, Chie Takada, Yui Suzuki, Itaru Yamaguchi, Katsumi Takaba, Naoya Kimoto
Publikováno v:
Experimental and Toxicologic Pathology. 67:41-51
Common marmosets (Callithrix jacchus) have become a useful animal model, particularly for development of biopharmaceuticals. While various renal failure models have been established in rodents, there is currently no acceptable model in marmosets. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5928180a78d5a1bef534cc10a0ab475e
https://doi.org/10.1016/j.etp.2014.09.007
https://doi.org/10.1016/j.etp.2014.09.007
Publikováno v:
Biological & Pharmaceutical Bulletin. 38:1070-1075
We have developed a simple protocol for inducing the myocardial differentiation of human induced pluripotent stem (iPS) cells. Human iPS cell-derived embryonic bodies (EBs) were treated with a combination of activin-A, bone morphogenetic protein-4 an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8371b05a7ff1972c762e754bab8d5c07
https://doi.org/10.1248/bpb.b14-00761
https://doi.org/10.1248/bpb.b14-00761
Autor:
Kensuke Myojo, Itaru Yamaguchi, Chie Takada, Hiroko Sanada, Katsumi Takaba, Minami Imaizumi, Yui Suzuki, Koji Saeki, Atsuko Takami, Naoya Kimoto, Jyoji Yamate
Publikováno v:
Journal of Toxicologic Pathology. 27:183-195
To assess the relevance and availability of subtotal nephrectomized common marmoset monkeys as a chronic renal failure (CRF) model, we observed for 26 weeks the pathophysiological condition of female marmosets subjected to five-sixth surgical nephrec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00e328f941505e691fe774fd9aba82a7
https://doi.org/10.1293/tox.2013-0055
https://doi.org/10.1293/tox.2013-0055
Publikováno v:
Journal of Pharmacological Sciences, Vol 124, Iss 2, Pp 201-207 (2014)
The mouse embryonic stem cell test (mEST) is used to assess the embryotoxicity of drug candidates by evaluating the effects on the cardiac differentiation of stem cells. However, thalidomide embryotoxicity has not yet been reported using the mEST. To
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fd1d939a61088ab7b18ae02faa05120
https://doi.org/10.1254/jphs.13162fp
https://doi.org/10.1254/jphs.13162fp
Autor:
Kensuke Myojo, Minami Imaizumi, Tomomi Yoneshige, Eri Sudo, Yui Suzuki, Hiroshi Okumura, Atsuko Takami, Itaru Yamaguchi, Sayaka Ootsuka, Naoya Kimoto, Chie Takada, Koji Saeki, Katsumi Takaba, Hiroko Sanada
Publikováno v:
Journal of Toxicologic Pathology. 26:301-307
We histopathologically and immunohistochemically investigated a case of malignant lymphoma that spontaneously developed in a male common marmoset at two years of age. Beginning at two years four months of age, the animal had an enlargement of the sub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4202aefedd407edf2e68f31679ba597
https://doi.org/10.1293/tox.26.301
https://doi.org/10.1293/tox.26.301
Autor:
Koji Saeki, Chie Takada, Teruyoshi Imada, Shigehisa Katsumata, Minami Imaizumi, Naoya Kimoto, Yui Suzuki, Sachiko Iwamoto, Itaru Yamaguchi, Katsumi Takaba, Hiroshi Okumura, Kensuke Myojo
Publikováno v:
Journal of Toxicologic Pathology
This study histopathologically and immunohistochemically investigated a spontaneously occurring single mass subcutaneously located in the left lower abdomen of a female BALB/cAJcl−nu/+ mouse at 10 weeks of age. The mass was about 20 × 15 × 10 mm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24831d3ba3b2176bd6f8be32a400f4f2
https://doi.org/10.1293/tox.25.265
https://doi.org/10.1293/tox.25.265
Autor:
Takako Kadowaki Horita, Koji Yamada, Yoshinori Nagata, Makoto Takayama, Tomoyuki Kanda, Shusuke Takahashi, Nobuyuki Suzuki, Katsumi Takaba
Publikováno v:
Brain Research. 1421:110-120
We have previously demonstrated that perindopril, an angiotensin-converting enzyme (ACE) inhibitor, ameliorated the cognitive deficits in Alzheimer's disease model animals, independently of its anti-hypertensive effect. In this study, we again invest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e405d974ff42939fe2acdc7f6c1244f
https://doi.org/10.1016/j.brainres.2011.09.016
https://doi.org/10.1016/j.brainres.2011.09.016
Publikováno v:
Biotechnic & Histochemistry
The effects of prolonged water washing after fixation for 48 h in 10% (v/v) phosphate-buffered neutral formalin on the quality of representative histological staining methods were evaluated using samples of liver, kidney, spleen and thymus collected
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7e1d28d89b20780dee0acf7f74149cd
https://doi.org/10.3109/10520295.2011.613410
https://doi.org/10.3109/10520295.2011.613410
Autor:
Chie Takada, Katsumi Takaba, Katsuya Kobayashi, Yuko Takashima, Haruhiko Manabe, Daisuke Harada, Yukino Nosaka
Publikováno v:
International Immunopharmacology. 9:55-62
Due to the broad anti-inflammatory and immunomodulatory actions of phosphodiesterase (PDE) 4 inhibitors, it has been proposed that PDE4 inhibitors might be efficacious for skin disorders such as atopic dermatitis. KF66490 is a newly developed PDE4 in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::511218e3ecbdd09dd05e61f1b1f6a1de
https://doi.org/10.1016/j.intimp.2008.09.011
https://doi.org/10.1016/j.intimp.2008.09.011