Zobrazeno 1 - 10
of 222
pro vyhledávání: '"Katsumi Kakinuma"'
Autor:
Satoru Watanabe, Hirofumi Yoshikawa, Fumitaka Kudo, Toshifumi Hirayama, Tadashi Eguchi, Hiroaki Ozawa, Kaori Nimura-Matsune, Hiroaki Kato, Katsumi Kakinuma
Publikováno v:
Bioscience, biotechnology, and biochemistry. 82(1)
Owing to their photosynthetic capabilities, there is increasing interest in utilizing cyanobacteria to convert solar energy into biomass. 2-Deoxy-scyllo-inosose (DOI) is a valuable starting material for the benzene-free synthesis of catechol and othe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e389fd328c9e21829eae666c9cfdceb
https://pubmed.ncbi.nlm.nih.gov/29297252
https://pubmed.ncbi.nlm.nih.gov/29297252
Autor:
Toshifumi Hirayama, Hideyuki Tamegai, Katsumi Kakinuma, Tadashi Eguchi, Fumitaka Kudo, Kazumasa Kojima
Publikováno v:
The Journal of Antibiotics. 59:358-361
A part of the new biosynthetic gene cluster for 2-deoxystreptamine-containing antibiotics was identified from Streptoalloteichus hindustanus. The alloH gene in the gene cluster was deduced to encode 2-deoxy-scyllo-inosose synthase and the expressed p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14160602d7933b8f66475a805a922d03
https://doi.org/10.1038/ja.2006.51
https://doi.org/10.1038/ja.2006.51
Publikováno v:
Tetrahedron Lett.. 47(No. 10):1529-1532
The excited thioesterase (TE) domain from the vicenistatin polyketide synthase (PKS) efficiently catalyzed the macrolactam formation of the N-acetylcysteamine thioester of the seco-amino acid of the aglycon vicenilactam. This result indicates that th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc44ca27b16efd3f31be3f3a7562e89a
http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100541861
http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100541861
Publikováno v:
The Journal of Antibiotics. 58:766-774
NeoA, B, and C encoded in the neomycin biosynthetic gene cluster have been enzymatically confirmed to be responsible to the formation of 2-deoxystreptamine (DOS) in Streptomyces fradiae. NeoC was functionally characterized as 2-deoxy-scyllo-inosose s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::800cd9853ff355ea68a6cfdc45bb79c2
https://doi.org/10.1038/ja.2005.104
https://doi.org/10.1038/ja.2005.104
Publikováno v:
Tetrahedron Letters. 46:6187-6190
New aglycon switch approach using glycosyltransferase VinC was explored to create unnatural glycosides from natural glycoside in one-pot reaction. This aglycon switch comprises from two reactions, where NDP-vicenisamine generated in situ from natural
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dcb8e5934dda1aed2aed8457ba75873
https://doi.org/10.1016/j.tetlet.2005.07.083
https://doi.org/10.1016/j.tetlet.2005.07.083
Publikováno v:
The Journal of Antibiotics. 58:468-472
The macrolactam antibiotic vicenistatin, produced in Streptomyces halstedii HC34, is biosynthesized by the polyketide pathway, using a unique 3-methylaspartate-derived molecule as starter unit. The vinI gene in the vicenistatin biosynthetic gene clus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04de4d7652802cb2556302efc0a06203
https://doi.org/10.1038/ja.2005.62
https://doi.org/10.1038/ja.2005.62
Autor:
Tadashi Eguchi, Fumitaka Kudo, Hideyuki Tamegai, Mario Numakura, Katsumi Kakinuma, Hideki Yamamoto
Publikováno v:
The Journal of Antibiotics. 58:373-379
Butirosin produced by Bacillus circulans is among the clinically important 2-deoxystreptamine containing aminoglycoside antibiotics and its unique structure is found in (S)-4-amino-2-hydroxyburyric acid substituted at C-1 of 2-deoxystreptamine. Recen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::542e60104d92809de1d37dc0fddec47b
https://doi.org/10.1038/ja.2005.47
https://doi.org/10.1038/ja.2005.47
Autor:
Mieko Kuwahara, Hideyuki Tamegai, Tadashi Eguchi, Fumitaka Kudo, Kenichi Yokoyama, Kousuke Inomata, Katsumi Kakinuma
Publikováno v:
Journal of the American Chemical Society. 127:5869-5874
The doubly functional aminotransferase BtrS in the 2-deoxystreptamine (DOS) biosynthesis, in which two transaminations are involved, was characterized by a genetic as well as a chemical approach with the heterologously expressed enzyme. The gene disr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45229cbb68d5734c1b7eaaa03eefd2a0
https://doi.org/10.1021/ja0445948
https://doi.org/10.1021/ja0445948
Autor:
Hideki Aizawa, Norihiko Misawa, Tomohisa Kuzuyama, Hideyuki Tamegai, Tadashi Eguchi, Yasumasa Dekishima, Katsumi Kakinuma, Haruo Seto
Publikováno v:
Tetrahedron. 61:2027-2035
Carotenoids are important natural pigments produced by various microorganisms and plants. Specific deuterium-labeling of these compounds is invaluable in biochemical and physiochemical research. In this paper, preparation of highly deuterated zeaxant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dabcd18aa25456a209eb9686e4bba25
https://doi.org/10.1016/j.tet.2004.12.056
https://doi.org/10.1016/j.tet.2004.12.056
Publikováno v:
Journal of the American Chemical Society. 127:1711-1718
Aminoglycoside antibiotics are composed of aminosugars and a unique aminocyclitol aglycon including 2-deoxystreptamine (DOS), streptidine, actinamine, etc., and nucleotidylyltransferases, sugar modifying enzymes, and glycosyltransferases appear to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e0f3d8ae7ec518a91ded0f3da69a60f
https://doi.org/10.1021/ja044921b
https://doi.org/10.1021/ja044921b