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Autor:
Maki Kuwahara, Nobuaki Nakashima, Toshinori Yoshida, Haruka Horiuchi, Takanori Harada, Yukiko Kashimoto, Naofumi Takahashi, Aya Ohnuma, Katsumi Ishitsuka
Publikováno v:
Toxicologic pathology. 39(7)
Dimethylarsinic acid (DMAV), the major excreted metabolite of inorganic arsenic, is carcinogenic to the rat urinary bladder. Oxidative stress has been proposed as one possible mechanism of DMAV-induced carcinogenesis. The authors determined whether t