Zobrazeno 1 - 10
of 226
pro vyhledávání: '"Katsumi, Matsuzaki"'
Publikováno v:
ACS Omega, Vol 6, Iss 17, Pp 11458-11465 (2021)
Externí odkaz:
https://doaj.org/article/ebac68df738547eea83db9d50870c4ab
Publikováno v:
ChemBioChem. 23
Small residue-mediated interhelical packing is ubiquitous in helical membrane proteins: however, the lipid dependence of its stability remains unclear. We previously demonstrated that the introduction of a GXXXG sequence in the middle of de novo -des
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c524b2bdcfbdfe12f195aeaac9c5c4b2
https://doi.org/10.1002/cbic.202200160
https://doi.org/10.1002/cbic.202200160
Publikováno v:
ACS Omega, Vol 6, Iss 17, Pp 11458-11465 (2021)
ACS Omega
ACS Omega
Protein-protein interactions between transmembrane helices are essential elements for membrane protein structures and functions. To understand the effects of peptide sequences and lipid compositions on these interactions, single-molecule experiments
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f5a241bcaf788559d38df9bf17cee17
https://doaj.org/article/ebac68df738547eea83db9d50870c4ab
https://doaj.org/article/ebac68df738547eea83db9d50870c4ab
Publikováno v:
ACS Infectious Diseases. 6:2271-2278
Antimicrobial peptides (AMPs) are promising candidates for new therapeutics to combat the emergence of an increasing number of multidrug-resistant pathogens. However, a major obstacle to the systemic application of AMPs is their possible toxicity. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0732eb5f9d14e2589e801f8f1151d82b
https://doi.org/10.1021/acsinfecdis.0c00387
https://doi.org/10.1021/acsinfecdis.0c00387
Autor:
Katsumi Matsuzaki
Publikováno v:
Chemicalpharmaceutical bulletin. 70(1)
Biomembranes composed of various proteins and lipids play important roles in cellular functions, such as signal transduction and substance transport. In addition, some bioactive peptides and pathogenic proteins target membrane proteins and lipids to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da295d0c2822df7a95adeb83e5ea2f4b
https://pubmed.ncbi.nlm.nih.gov/34980725
https://pubmed.ncbi.nlm.nih.gov/34980725
Publikováno v:
ACS infectious diseases. 7(10)
Antimicrobial peptides (AMPs) are promising candidates for anti-infective drugs. The majority of AMPs are considered to disrupt the lipid matrix of bacterial membranes, exerting bactericidal activity. A number of biophysical studies have been carried
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d174c5887be4cfc07221763074317ea
https://pubmed.ncbi.nlm.nih.gov/34514779
https://pubmed.ncbi.nlm.nih.gov/34514779
Autor:
Yoshihiko Miyata, Katsumi Matsuzaki, Mami Yamamoto, Toshimichi Fujiwara, Chojiro Kojima, Masaru Hoshino, Futoshi Ihama
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1867:813-820
Cdc37 is a protein kinase-targeting molecular chaperone, which cooperates with Hsp90 to assist the folding, assembly and maturation of various signaling kinases. It consists of three distinct domains: the N-terminal, middle, and C-terminal domain. Wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b849b90d2b98af5b8ab905f0e9f83b6b
https://doi.org/10.1016/j.bbapap.2019.06.007
https://doi.org/10.1016/j.bbapap.2019.06.007
Autor:
Katsumi Matsuzaki, Yoshiaki Yano
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1861:1011-1017
In situ investigations in living cell membranes are important to elucidate the dynamic behaviors of membrane proteins in complex biomembrane environments. Protein-specific labeling is a key technique for the detection of a target protein by fluoresce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdb17793d0f5d59de9b9cc5547fbba94
https://doi.org/10.1016/j.bbamem.2019.02.009
https://doi.org/10.1016/j.bbamem.2019.02.009
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1863(3)
The tertiary structures and conformational dynamics of transmembrane (TM) helical proteins are maintained by the interhelical interaction network in membranes, although it is complicated to analyze the underlying driving forces because the amino acid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57c085404fc33449dd5351fd9e762ff1
http://hdl.handle.net/2433/266569
http://hdl.handle.net/2433/266569
Autor:
Katsumi Matsuzaki
Publikováno v:
Biochimica et biophysica acta. 1862(8)
It is widely accepted that the abnormal self-association of amyloid β-protein (Aβ) is central to the pathogenesis of Alzheimer's disease, the most common form of dementia. Accumulating evidence, both in vivo and in vitro, suggests that the binding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34f4fcf17065bf2fb1afe41b5ae5bc02
http://hdl.handle.net/2433/251422
http://hdl.handle.net/2433/251422