Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Katsuichiro Komatsu"'
Autor:
Mayumi Nakayama, Hiroyuki Horiuchi, Asumi Sugahara, Kiyoshi Kawai, Shigefumi Kuwahara, Daisuke Hagiwara, Tomonori Fujioka, Hideaki Umeyama, Katsuichiro Komatsu, Akira Yoshimi, Keietsu Abe, Masaru Enomoto, Takuya Katayama, Ken Miyazawa, Fumio Shoji
Publikováno v:
Applied and environmental microbiology. 85(10)
The cell wall integrity signaling (CWIS) pathway is involved in fungal cell wall biogenesis. This pathway is composed of sensor proteins, protein kinase C (PKC), and the mitogen-activated protein kinase (MAPK) pathway, and it controls the transcripti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e6a0c068bb5728a352f03f267464150
https://pubmed.ncbi.nlm.nih.gov/30902853
https://pubmed.ncbi.nlm.nih.gov/30902853
Autor:
Saori Komada, Hiroshi Tomoda, Yuichiro Nakamura, Hideaki Umeyama, Katsuichiro Komatsu, Junji Inokoshi
Publikováno v:
The Journal of antibiotics. 69(11)
Viridicatumtoxin and spirohexaline, small fungal molecules with a tetracyclic scaffold and an additional spirobicyclic ring in common, were found to inhibit bacterial undecaprenyl pyrophosphate (UPP) synthase with IC50 values of 4 and 9 μm, respecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d499eeb58ac0827c559cadcac099d8a7
https://pubmed.ncbi.nlm.nih.gov/27049441
https://pubmed.ncbi.nlm.nih.gov/27049441
Autor:
Inoue Tsutomu, Katsuyuki Ogura, Isao Umezawa, Osamu Hoshino, Yuasa Masayuki, Hiroshi Hara, Katsuichiro Komatsu, Hideji Itokawa, Takashi Inaba
Publikováno v:
Chemical and Pharmaceutical Bulletin. 43:1325-1335
In order to obtain a key compound (22a") for synthesis of RA-VII (1) and deoxybouvardin (2), construction of the 14-membered ring system was performed by means of thallium trinitrate-mediated oxidation of the tetrahalogeno amides 5-7. The dibromo dic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68b938fa812591d2457b2b4f109515aa
https://doi.org/10.1248/cpb.43.1325
https://doi.org/10.1248/cpb.43.1325
Publikováno v:
Proteins. 60(2)
In CAPRI Rounds 1 and 2, we assumed that because there are many ionic charges that weaken electrostatic interaction forces in living cells, the hydrophobic interaction force might be important entropically. As a result of Rounds 1 and 2, the predicti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af1f9a8e975bdb3e1f9e656d0f300147
https://pubmed.ncbi.nlm.nih.gov/15981245
https://pubmed.ncbi.nlm.nih.gov/15981245
Publikováno v:
Proteins. 52(1)
To predict protein-protein interactions, rough or coarse handling for the induced fit problem is proposed. Our method involves the overlap of two hydrophobic interactions as "third solvent clusters fitting." Predictions for binding sites and geometri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::808c132e3ce6001064e66cff8d4b298a
https://pubmed.ncbi.nlm.nih.gov/12784361
https://pubmed.ncbi.nlm.nih.gov/12784361
Publikováno v:
Proteins; 7/1/2003, Vol. 52 Issue 1, p15-18, 4p
Publikováno v:
Chemical and Pharmaceutical Bulletin. 33:2114-2121
A novel method of estimating Hansch's hydrophobic constant (log P) by making use of the solvent-accessible surface area (SA) with correction for the hydrophilic effect of any polar moiety (SH) is proposed. The correlation coefficient (r) between obse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b99577fdbce07b0f5949d417ab0abd2
https://doi.org/10.1248/cpb.33.2114
https://doi.org/10.1248/cpb.33.2114
Publikováno v:
Chemical and Pharmaceutical Bulletin. 24:1799-1806
The correlations of Hansch's hydrophobic constant (log P) with van der Waals volume (Vw) and with van der Waals surface area (Aw) were studied using 60 molecules including apolar organic compounds and inert gases, and superiority of Vw over Aw was re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4ec8cff54ba7e18e73df6c4df2d3b44
https://doi.org/10.1248/cpb.24.1799
https://doi.org/10.1248/cpb.24.1799
Publikováno v:
Analytica Chimica Acta. 133:625-636
The adaptive least-squares method (ALS) and linear discriminant analysis (LDA) were applied to structure—activity correlation studies including the antitumor activity of mitomycin derivatives, the relative binding affinities of 100 steroids for fiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26ac5c95b78aa892c831ff3079a8deb5
https://doi.org/10.1016/s0003-2670(01)95428-5
https://doi.org/10.1016/s0003-2670(01)95428-5
Publikováno v:
Quantitative Structure-Activity Relationships. 3:106-111
Robust regression methods were applied to 56 sets of structure-activity data collected from the literature. The methods included the Huber estimator, the sine estimator, the biweight estimator, and least-squares with a cut-off option. On the basis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::637bc2bc30180dd314fbe8b66759e788
https://doi.org/10.1002/qsar.19840030305
https://doi.org/10.1002/qsar.19840030305