Data from Increased Levels of Tetra-antennary N-Linked Glycan but Not Core Fucosylation Are Associated with Hepatocellular Carcinoma Tissue

Autor: Timothy Block, Eiji Miyoshi, Katsuhisa Noda, Alex Koszycki, Lucy Rodemich-Betesh, Mengjun Wang, Mary Ann Comunale, Hongyan Liang, Pamela Norton, Anand Mehta

Background: Alterations in glycosylation have long been associated with the development of cancer. In the case of primary hepatocellular carcinoma (HCC), one alteration that has often been associated is increased amounts of fucose attached to the N-g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53e4a1e85a3109c74dc58837aaf04c16
https://doi.org/10.1158/1055-9965.c.6515662

Increased Levels of Tetra-antennary N-Linked Glycan but Not Core Fucosylation Are Associated with Hepatocellular Carcinoma Tissue

Autor: Mengjun Wang, Anand Mehta, Hongyan Liang, Lucy Rodemich-Betesh, Pamela A. Norton, Mary Ann Comunale, Katsuhisa Noda, Alex Koszycki, Timothy M. Block, Eiji Miyoshi

Publikováno v: Cancer Epidemiology, Biomarkers & Prevention. 21:925-933

Background: Alterations in glycosylation have long been associated with the development of cancer. In the case of primary hepatocellular carcinoma (HCC), one alteration that has often been associated is increased amounts of fucose attached to the N-g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd2c45c6042b90effab25654b4ee1a4f
https://doi.org/10.1158/1055-9965.epi-11-1183

Contents Vol. 73, 2007

Autor: C.E. Nwogu, A.N. Tenekeci, Pierre Michel, Michihide Mitsumori, Kohkichi Hata, Mariana Capurro, S. Maddipatla, R.V. Iyer, Eiji Miyoshi, H.J. Stemmler, Rosangela Romano, A. Douglas-Jones, B. Kalischefski, Sylvie Negrier, D. Laessig, J. Robson, Domenico Germano, Wong Benjamin Chun Yu, Torello Lotti, Chen Minhu, Peixing Wu, Jie Zhang, G. Paganelli, Metin Karakok, Rafael Roesler, P.A. Fasching, Toshinao Onoda, Takatsugu Kan, Tsuneo Tanaka, Hideyuki Ohnuma, Yasuhito Tonomoto, M. Stauch, Sung Ho Choi, Hui Yan Li, R.E. Mansel, C. Poettgen, S. Raj, Yan Wang, Daniela Massi, Xiaoyan Yang, Thomas Krbek, B. Sakar, Bülent Akgul, H. Kynaston, Dipok Kumar Dhar, H. Kölbl, Satoshi Shiojima, Vincenzo De Giorgi, J.D. Black, Bin Zhou, Evangelos Karayiotis, Seungmin Bang, Hong-zhi Luo, Akira Myoumoto, Bing Xu, Hitoshi Nobumasa, Pu Wang, Serena Sestini, Go Watanabe, Yutaka Shimada, Ibrahim Sari, S.R. Davies, Tadashi Kadowaki, Si Young Song, Shinichi Miyamoto, Meletios A. Dimopoulos, Bai Aiping, G. Loewen, P. Maubach, Akira Miyauchi, Shen Benchang, F. Melchert, Shigemi Matsumoto, G. Morack, J. Alkhaddo, N. Natarajan, Atsushi Itami, Zong-guang Zhou, Luise Meurer, Lie Yang, Hai-yi Liu, Naofumi Nagasue, Kanako Yamanaka, Dirk Theegarten, Giulia Lo Russo, Gazi Comez, Aristotle Bamias, M.E. Reid, David Tougeron, Efstathios Kastritis, Eiji Tanaka, A. Chhabra, Sabine Levegruen, Marios Froudarakis, Andreas Koureas, Celalettin Camci, Yavuz Pehlivan, Jeong Youp Park, F. Eid, Dirk Jaeger, Gozoh Tsujimoto, N. Ramnath, A.U. Pande, G. Watkins, H.S. Fernando, H. Meerpohl, Mehmet Emin Kalender, Katsuhisa Noda, Helmut Teschler, Gilberto Schwartsmann, Xiao-Feng Sun, Genny Leporatti, M.A. Ustaoglu, Tetsuo Ito, Martin Stuschke, V. Heinemann, Alper Sevinc, Toshinori Sato, Noriko Okuyama, Bernard Paillot, Olivier Rigal, Yuan Li, Andreas Bockisch, M. Basaran, Nikos Antoniou, P. Dua, Sadako Yamagata, D. Mazhar, Hiroshi Yoshida, Wolfgang Stremmel, S. Saglam, Mei Hou, Wilfried Eberhardt, R.J. Menezes, N.F. Aykan, Michael Chrisofos, Hitoshi Matsumoto, C.M. Levea, Anastassios V. Koutsopoulos, Georgios Stamatis, Hideo Akiyama, Li Xiaoyan, Ling Wang, H. Hamidou, Maurie Markman, Luigi Manzione, Andreas Skolarikos, Yu-jian Zeng, Mario Dini, Jorge Filmus, A.K. Dixon, Frédéric Di Fiore, Daniela Baumann Cornelio, M. Emin Kalender, Stephen J. Meltzer, Wang Jinhui, A. Argon, Tatsuya Yamagata, M. Gumus, Motoshige Higashiyama, B. Weber, Song Xin, G. Alivizatos, Jiang Zhu, Sung Hoon Noh, Thomas Gauler, Yasuhiro Ito, Thomas R. W. Herrmann, Christina Herrmann, Jinghai Zhang, Yong Soo Kim, U. Vehling-Kaiser, H. Mehmet Turk, Z. Ustuner, Hilmar Kuehl, Christelle De La Fouchardiere, Chen Huixin, Woo Jin Hyung, Georgia Karpathiou, M.M. Javle, Olivia Diaz, Evangelia Argiana, A. Scharl, Ulrich Abel, George Lainakis, Fumiaki Sato, W.G. Jiang, M.V. Williams, Romain Coriat, G.Y. Yang, N. Guney, Shiori Tomoda, A. Rani, Françoise Desseigne, Jun-min Song, Mitsuo Tachibana

Publikováno v: Oncology. 73:I-VI

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7dc55919e8cd065fc6e64283f096edec
https://doi.org/10.1159/000140682

Dysregulation of TGF-β1 receptor activation leads to abnormal lung development and emphysema-like phenotype in core fucose-deficient mice

Autor: Masaru Okabe, Carlos López-Otín, Naofumi Uozumi, Yoshiaki Tomiyama, Steven D. Shapiro, Katsuhisa Noda, Shinji Ihara, Jianguo Gu, Xiangchun Wang, Motoko Takahashi, Akihiro Kondo, Tomoyuki Kuwaki, Eiji Miyoshi, Yukihiro Yamaguchi, Junichi Fujii, Yoshiya Aze, Miyako Nakano, Seung Ho Lee, Koichi Honke, Keiichiro Suzuki, Shinya Inoue, Yoshitaka Ikeda, Yoko Mizuno-Horikawa, Wenzhe Li, Naoyuki Taniguchi, Michio Asahi

Publikováno v: Proceedings of the National Academy of Sciences. 102:15791-15796

The core fucosylation (α1,6-fucosylation) of glycoproteins is widely distributed in mammalian tissues, and is altered under pathological conditions. To investigate physiological functions of the core fucose, we generated α1,6-fucosyltransferase ( F

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f1cdbb2d7b75f3ff0110d3555828c086
https://doi.org/10.1073/pnas.0507375102

The Enzymatic Basis for the Conversion of Nonfucosylated to Fucosylated α-Fetoprotein by Acyclic Retinoid Treatment in Human Hepatoma Cells: Activation of α1-6 Fucosyltransferase

Autor: Yutaka Sasaki, Susumu Nakahara, Koichi Honke, Yoshimune Shiratori, Eiji Miyoshi, Takatoshi Kitada, Akinori Kasahara, Masatsugu Hori, Norio Hayashi, Cong Xiao Gao, Hisataka Moriwaki, Katsuhisa Noda, Naoyuki Taniguchi

Publikováno v: Tumor Biology. 23:202-211

The purpose of the present study was to investigate the mechanism by which nonfucosylated alpha-fetoprotein (AFP) is converted to fucosylated AFP in human hepatoma cell lines exposed to acyclic retinoid (AR), an effective drug for the secondary preve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::807635e49725a5ce98fbc7cb1acbe347
https://doi.org/10.1159/000067253