Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Katsuhiro Ono"'
Autor:
Ayumi Shuto, Senji Okuno, Kyoko Norimine, Hisanori Okazaki, Katsuhiro Ono, Midori Taguchi, Kenjiro Yamakawa, Shigeichi Shoji, Tomoyuki Yamakawa, Katsuhito Mori, Masanori Emoto
Publikováno v:
Nihon Toseki Igakkai Zasshi. 56:161-166
Autor:
Katsuyuki Kito, Masaki Iwasa, Osam Inatomi, Takayuki Imai, Masaki Murata, Katsuhiro Ono, Akira Andoh, Masahiro Kawahara
Publikováno v:
Clinical journal of gastroenterology. 13(6)
We report a case of life-threatening bleeding from the small intestine accompanied by lower coagulation factor XIII (FXIII) activity. A 43-year-old man was admitted because of continuous small intestinal bleeding. He had no family or past history of
Autor:
Kazuhiko Nakagawa, Nobuyuki Yamamoto, Yuichiro Ohe, Isamu Okamoto, Kaoru Kubota, Naoyuki Nogami, Hidetoshi Yamaya, Haruyasu Murakami, Katsuhiro Ono
Publikováno v:
Investigational New Drugs. 30:1132-1137
Background Nanoparticle albumin-bound paclitaxel (nab-paclitaxel) is a Cremophor EL–free formulation of paclitaxel newly designed to avoid solvent-related toxicities. We have evaluated the safety, tolerability, pharmacokinetics, and tumor response
Autor:
Minqi Li, Tomoyo Sasaki, Ubaidus Sobhan, Kimimitsu Oda, Taku Kojima, Katsuhiro Ono, Junko Shimomura, Norio Amizuka, Paulo Henrique Luiz de Freitas
Publikováno v:
Biomedical Research. 28:127-137
The purpose of this study was to examine the localization of macrophages, B-lymphocytes and osteoclasts in tumoral lesions of mammary carcinoma metastasized to bone of non-immunocompromised mice. Mouse mammary carcinoma cells (BALB/c-MC) were injecte
Publikováno v:
Bone. 33:798-804
The inducible prostaglandin (PG) synthesis enzyme, cyclooxygenase-2 (COX-2), is involved in osteoclast (OC) formation in cocultures of mouse mammary cancer cell lines (MMT060562 or BALB/c-MC) and bone marrow cells through production of PGE 2 . There
Autor:
Eisuke Tsuda, Kazuo Motoyoshi, N. Fujise, Kanji Higashio, Katsuhiro Ono, Naokazu Nagata, Mikio Yamamoto, S.-I. Mochizuki, Takehiko Murakami, Takuhiko Akatsu, Masami Nishikawa
Publikováno v:
Bone. 23:495-498
Osteoclastogenesis inhibitory factor (OCIF) is a novel secreted protein that inhibits osteoclastogenesis both in vitro and in vivo. In this study, we examined the effects of OCIF on serum calcium (Ca) concentrations in normal mice and in hypercalcemi
Autor:
Nariyoshi Shinomiya, Takehiko Murakami, Miyuki Nishikawa, Kanji Higashio, Kyoji Yamaguchi, Takuhiko Akatsu, Michiko Yamamoto, Eisuke Tsuda, Kazuo Motoyoshi, Katsuhiro Ono, Shinichi Mochizuki, Naokazu Nagata, Masahiko Kinosaki
Publikováno v:
Biochemical and Biophysical Research Communications. 250:229-234
Osteoclastogenesis inhibitory factor (OCIF) was originally identified as a factor inhibiting osteoclast (OC) formation. The number of OC in rats treated with OCIF decreased, suggesting that OCIF inhibits OC formation in vivo; however, it is also poss
Autor:
Miyuki Nishikawa, Mikio Yamamoto, Takehiko Murakami, Seiki Wada, Katsuhiro Ono, Takuhiko Akatsu, Naokazu Nagata, Nariaki Matsuura, Nobuo Kugai
Publikováno v:
Bone. 23:27-32
We recently reported that numerous osteoclasts (OC) were formed in cocultures of some mouse cancer cell lines and bone marrow cells. In this study, we examined mechanisms by which one of the cell lines, BALB/c-MC, induces OC. BALB/c-MC dose dependent
Autor:
Yasuyuki Katayama, Katsuhiro Ono, Tatsuya Tamura, Nobuo Kugai, Naokazu Nagata, Takuhiko Akatsu, Michiko Yamamoto, Miyuki Nishikawa
Publikováno v:
Journal of Bone and Mineral Research. 13:400-408
Osteoclastic bone resorption increases at the site of bone metastasis, but little is known about how tumor cells induce osteoclast (OC) recruitment in the bone marrow microenvironment. To clarify this point, we examined the effects of various mouse t
Publikováno v:
Japanese Journal of Cancer Research : Gann
Menogaril, an anthracycline derivative, has been shown to possess antitumor activity in experimental animal systems, and is now under phase II clinical studies. However, its mechanism of action has not been elucidated. We have found that it inhibits