Výsledky vyhledávání - "Katsuhiro, Zen"

IL-4-producing CD8+ T cells may be an immunological hallmark of chronic GVHD

Autor: Yonsu Son, Ryuichi Amakawa, Katsuhiro Zen, Kengo Nakamura, Yuji Kishimoto, S. Fukuhara, Michihiko Miyaji, Masashi Takebayashi, Tomoki Ito, Noriaki Matsumoto, K Nakai, Kenichirou Tajima

Publikováno v: Bone Marrow Transplantation. 36:639-647

Chronic graft-versus-host disease (cGVHD) occurs in approximately 60-80% of those who survive over 100 days after allogeneic hematopoietic stem cell transplantation (allo-HSCT). However, the pathophysiology of cGVHD is poorly understood. To gain more

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8559c91beaf7bf9ba5c3677444559098
https://doi.org/10.1038/sj.bmt.1705107

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Membranous Nephropathy Associated with Donor Lymphocyte Infusion following Allogeneic Bone Marrow Transplantation

Autor: Shirou Fukuhara, Katsuhiro Zen, Yasukiyo Mori, Yuji Kishimoto, Yasuhiko Miyazaki, Noriaki Matsumoto, Noriko Kishimoto, Ryuichi Amakawa

Publikováno v: International Journal of Hematology. 78:262-265

Nephrotic syndrome after hematopoietic stem cell transplantation (HSCT) followed by donor lymphocyte infusion (DLI) has never been described. We report the case of a myelodysplastic syndrome (MDS) patient who developed nephrotic syndrome with membran

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9efbb332d73e40ec7b092b5ab8e68d15
https://doi.org/10.1007/bf02983805

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NF-κB Activation Is Required for Human Endothelial Survival during Exposure to Tumor Necrosis Factor-α but Not to Interleukin-1β or Lipopolysaccharide

Autor: Thomas Eunson, Mark A. Kay, Katsuhiro Zen, Xianwu Li, Christopher B. Wilson, Aly Karsan, Esther Yee, Joan C. Tupper, April Stempien-Otero, John M. Harlan, Robert K. Winn

Publikováno v: Journal of Biological Chemistry. 274:28808-28815

In the presence of a protein synthesis inhibitor, cycloheximide, tumor necrosis factor-alpha (TNF-alpha), interleukin 1-beta (IL-1beta), or lipopolysaccharide (LPS) induces human umbilical vein endothelial cells (HUVECs) to undergo apoptosis, suggest

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bec9e05b5538b509661e296c8bfc37e2
https://doi.org/10.1074/jbc.274.40.28808

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Lipopolysaccharide-Induced NF-κB Activation in Human Endothelial Cells Involves Degradation of IκBα but Not IκBβ

Autor: Katsuhiro Zen, Aly Karsan, Thomas Eunson, John M. Harlan, Esther Yee

Publikováno v: Experimental Cell Research. 243:425-433

We studied the signal transduction pathways involved in NF-kappaB activation and the induction of the cytoprotective A20 gene by lipopolysaccharide (LPS) in human umbilical vein endothelial cells (HUVEC). LPS induced human A20 mRNA expression with a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2e55f41e6739944fe4675d19c5699000
https://doi.org/10.1006/excr.1998.4162

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Monocyte-Derived Macrophages Prime Peripheral T Cells to Undergo Apoptosis by Cell-Cell Contact via ICAM -1 /LFA-1-Dependent Mechanism

Autor: Jun Ogata, Katsuhiro Zen, Junichi Masuda

Publikováno v: Immunobiology. 195:323-333

We designed the present study to clarify the mechanism of superantigen-induced apoptosis of human mature T cells and to elucidate the pivotal roles of monocyte-derived macrophages in induction of T cell apoptosis. Exposure of unfractionated human per

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27ed0fe745316bdc02661a61f5fa8dd3
https://doi.org/10.1016/s0171-2985(96)80049-0

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Gene Expression of Monocyte Chemoattractant Protein-1 in Human Monocytes Is Regulated by Cell Density through Protein Tyrosine Kinase and Protein Kinase C

Autor: Jun Ogata, Katsuhiro Zen, Junichi Masuda, Chiya Kosaka, Toshiyuki Sasaguri

Publikováno v: Experimental Cell Research. 215:172-179

The present study investigated the signal transduction pathways leading to the gene expression for monocyte chemoattractant protein-1 (MCP-1) in human monocytes. By Northern blot analysis, MCP-1 mRNA was undetectable in freshly isolated monocytes, bu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b09f3eecdef2b507716dda0aac0467e2
https://doi.org/10.1006/excr.1994.1329

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Protein Kinase C-Mediated Inhibition of Cyclin A Expression in Human Vascular Endothelial Cells

Autor: Kentaro Shimokado, Katsuhiro Zen, Jun Ogata, Chiya Kosaka, Toshiyuki Sasaguri, Junichi Masuda, Tasuku Yokota

Publikováno v: Biochemical and Biophysical Research Communications. 193:991-998

Proliferation of cultured human vascular endothelial cells may be negatively regulated by the protein kinase C (PKC) pathway, because phorbol 12-myristate, 13-acetate (PMA) inhibits DNA synthesis and cell population doubling in PKC-retaining cells, b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::819f23fb3e5f6b997327f95d983858f4
https://doi.org/10.1006/bbrc.1993.1723

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Interferon-γ suppresses PDGF production from THP-1 cells and blood monocyte-derived macrophages

Autor: Katsuhiro Zen, Kentaro Shimokado, Junichi Masuda, Chiya Kosaka, Tasuku Yokota, Toshiyuki Sasaguri, Jun Ogata

Publikováno v: Atherosclerosis. 97:75-87

Involvement of the immunological mechanisms in atherogenesis has recently been suggested by immunohistological detection of macrophages and T lymphocytes in atherosclerotic lesions. In the present study, we have investigated the regulatory effect of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2911d94947f6040c3129995d9b02ca5
https://doi.org/10.1016/0021-9150(92)90053-j

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[Splenic marginal zone lymphoma associated with antiphospholipid antibodies]

Autor: Takashi, Yokoi, Shinichiro, Mori, Hiroyuki, Sugimoto, Yutaka, Komiyama, Yoshiko, Uemura, Riki, Tanijiri, Kunihisa, Nakai, Noriaki, Matsumoto, Katsuhiro, Zen, Ryuichi, Amakawa, Yuji, Kishimoto, Masahiro, Ieko, Hakuo, Takahashi, Shirou, Fukuhara

Publikováno v: [Rinsho ketsueki] The Japanese journal of clinical hematology. 45(10)

A 61-year-old woman experienced a high fever with anemia and APTT prolongation after suffering a herpes zoster virus infection. Physical examination revealed a large splenomegaly without lymphadenopathy. Laboratory evaluations were positive for lupus

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bbebac1d53b7282c16ec6e574df35065
https://pubmed.ncbi.nlm.nih.gov/15553043

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Intra-arterial steroid-injection therapy for steroid-refractory acute graft-versus-host disease with the evaluation of angiography

Autor: Yuji Kishimoto, Masahiro Fujimoto, N Tanigawa, Kenichirou Tajima, Katsuhiro Zen, Noriaki Matsumoto, Ryuichi Amakawa, Shosaku Nomura, S. Fukuhara, K Nakai, S Sawada

Publikováno v: Bone marrow transplantation. 33(12)

We treated three patients with steroid-refractory acute graft-versus-host disease (aGVHD) with intra-arterial steroid-injection therapy (IAST). Two patients with gut aGVHD received IAST into both superior and inferior mesenteric arteries, while one p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97471b306896c69f4d53bef6fd4319ac
https://pubmed.ncbi.nlm.nih.gov/15094752

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