Zobrazeno 1 - 10
of 376
pro vyhledávání: '"Katsuhiko SASAKI"'
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 1956-1965 (2021)
Principal component analysis (PCA) is a useful tool for omics analysis to identify underlying factors and visualize relationships between biomarkers. However, this approach is limited in addressing life complexity and further improvement is required.
Externí odkaz:
https://doaj.org/article/38238470e47247bab80a767633a4e84d
Autor:
Norifusa Iwahashi, Hironobu Umakoshi, Masatoshi Ogata, Tazuru Fukumoto, Hiroki Kaneko, Eriko Terada, Shunsuke Katsuhara, Naohiro Uchida, Katsuhiko Sasaki, Maki Yokomoto-Umakoshi, Yayoi Matsuda, Ryuichi Sakamoto, Yoshihiro Ogawa
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Whole transcriptome profiling is a promising technique in adrenal studies; however, whole transcriptome profiling of adrenal disease using formalin-fixed paraffin-embedded (FFPE) samples has to be further explored. The aim of this study was to evalua
Externí odkaz:
https://doaj.org/article/26c01cd022f74660b5f18ef080dd8da4
Autor:
Kohei FUKUCHI, Ken-ichi OHGUCHI, Katsuhiko SASAKI, Yorimasa TSUBOTA, Takuro MITA, Wataru NAGAI, Kouji OHSATO, Nobuaki SHINYA
Publikováno v:
Nihon Kikai Gakkai ronbunshu, Vol 87, Iss 895, Pp 20-00378-20-00378 (2021)
In order to evaluate low cycle fatigue life under thermo-mechanical loading including high temperature regions, it is necessary to understand the basic deformation characteristics of a target material. In the case of thermo-mechanical loading, especi
Externí odkaz:
https://doaj.org/article/7d1e4afe90a74ec69e57f24868779b67
Autor:
Katsuhiko Sasaki, Kazuhito Gotoh, Sho Miake, Daiki Setoyama, Mikako Yagi, Ko Igami, Takeshi Uchiumi, Donchon Kang
Publikováno v:
EBioMedicine, Vol 20, Iss C, Pp 161-172 (2017)
Sepsis is a major cause of morbidity and mortality in seriously ill patients and mitochondrial dysfunction is associated with poor outcomes in septic patients. Although interleukin-6 (IL-6) is a good prognostic marker for sepsis, the relationship bet
Externí odkaz:
https://doaj.org/article/67e14ef3cd8b424cb629d03cffd8231d
Publikováno v:
Journal of Advanced Mechanical Design, Systems, and Manufacturing, Vol 13, Iss 3, Pp JAMDSM0066-JAMDSM0066 (2019)
In press processing, quality inspection of a product is often carried out for each lot in the post process stage. When a failure occurs, it may result in a large number of defective products due to the fast processing speed. In order to prevent this,
Externí odkaz:
https://doaj.org/article/6ab6c93382c94350bcf26bcb0a108423
Publikováno v:
Mechanical Engineering Journal, Vol 6, Iss 5, Pp 19-00137-19-00137 (2019)
The fatigue life of solder alloys for the slow-fast cyclic loading condition is much shorter than that for the fast-slow cyclic loading condition, despite the two loading conditions having almost the same inelastic strain amplitudes. This means that
Externí odkaz:
https://doaj.org/article/1c36fcb075dd406195517f8baec13949
Autor:
Kazuhito Gotoh, Takafumi Morisaki, Daiki Setoyama, Katsuhiko Sasaki, Mikako Yagi, Ko Igami, Soichi Mizuguchi, Takeshi Uchiumi, Yoshinori Fukui, Dongchon Kang
Publikováno v:
Cell Reports, Vol 25, Iss 7, Pp 1800-1815.e4 (2018)
Summary: Dendritic cell (DC) maturation induced by Toll-like receptor agonists requires activation of downstream signal transduction and metabolic changes. The endogenous metabolite citrate has recently emerged as a modulator of DC activation. Howeve
Externí odkaz:
https://doaj.org/article/6c1e87d4e40d4ffc823458723ec76953
Publikováno v:
Mechanical Engineering Journal, Vol 5, Iss 3, Pp 18-00001-18-00001 (2018)
Aluminum (Al) based composites containing vapor-growth carbon fibers (VGCF) and carbon nanotubes (CNT) has been developed by authors for a decade using spark plasma sintering (SPS). It has been clarified that the thermal conductivity of the composite
Externí odkaz:
https://doaj.org/article/3e43a52ac81d443494b23b986e49f4f9
Publikováno v:
Mechanical Engineering Journal, Vol 4, Iss 4, Pp 17-00266-17-00266 (2017)
Transformation plasticity significantly affects the stress distribution of a forging after heat-treatment. In this study, the transformation plasticity in a multi-phase transformation was measured experimentally. Two kinds of low-alloy steels were us
Externí odkaz:
https://doaj.org/article/8e2a0c0bfa46482c9554fc7a8382ba98
Publikováno v:
Nihon Kikai Gakkai ronbunshu, Vol 82, Iss 834, Pp 15-00520-15-00520 (2016)
During heat-treatment when forging a large shaft, stress occurs due to temperature change and phase transformation, and special care should be paid to the heat treatment in order to prevent cracking. Therefore it is important to use the finite elemen
Externí odkaz:
https://doaj.org/article/a8c42408005f4b8ea3f48a000ee644e1