Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Katsuhiko Miwa"'
Autor:
Hironobu Maezaki, Maki Miyamoto, Miki Hara, Norio Tada, Hisashi Fujita, Junya Shirai, Katsuhiko Miwa, Nobuki Sakauchi, Haruhiko Kuno, Nagako Kameoka, Ayumu Sato, Hideki Furukawa
Publikováno v:
Tetrahedron. 72:6334-6339
5-Chloro-1-(5-chloro-2-(methylsulfonyl)benzyl)-2-imino-1,2-dihydropyridine-3-carboxamide hydrochloride (TAK-259) is a novel, selective, and orally active α1D adrenoceptor antagonist with anti-urinary frequency effect. A metabolite (2) of TAK-259 was
Autor:
Hua Zou, Douglas R. Dougan, Kohji Fukatsu, Keiko Kakegawa, Masaaki Funata, Mitsuo Yamamoto, Clifford D. Mol, Katsuhiko Miwa, Akiyoshi Tani, Hiroyuki Watanabe, Makoto Kamata, Bi-Ching Sang, Jyun-ichi Sakamoto, Gyorgy Snell, Satoshi Endo, Tohru Yamashita, Toru Yamano
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 21:6314-6318
The co-crystal structure of the human acetyl-coenzyme A 2 (ACC2) carboxyl transferase domain and the reported compound CP-640186 (1b) suggested that two carbonyl groups are essential for potent ACC2 inhibition. By focusing on enhancing the interactio
Autor:
Toru Yamano, Tomomi Ikemoto, Mitsuru Kawada, Yukio Mizuno, Fumio Kikumoto, Katsuhiko Miwa, Shozo Yamamoto, Kiminori Tomimatsu, Tatsuya Ito
Publikováno v:
ChemInform. 31
Optically active esters were conveniently obtained from the corresponding racemic alcohols or esters by lipase-catalyzed transformation, followed by sulfation. Sulfation by sulfurtrioxide pyridine complex enabled facile isolation of optically active
Autor:
Shozo Yamamoto, Kiminori Tomimatsu, Katsuhiko Miwa, Fumio Kikumoto, Yukio Mizuno, Tomomi Ikemoto, Tatsuya Ito, Mitsuru Kawada, Toru Yamano
Publikováno v:
Chemistry Letters. 29:448-449
Optically active esters were conveniently obtained from the corresponding racemic alcohols or esters by lipase-catalyzed transformation, followed by sulfation. Sulfation by sulfurtrioxide pyridine complex enabled facile isolation of optically active