Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Katsufumi Dejima"'
Publikováno v:
iScience, Vol 26, Iss 10, Pp 108067- (2023)
Summary: Dietary supplied double-stranded RNA (dsRNA) can trigger RNA interference (RNAi) systemically in some animals, including the nematode Caenorhabditis elegans. Although this phenomenon has been utilized as a major tool for gene silencing in C.
Externí odkaz:
https://doaj.org/article/25df013d2cef4b9bb3ae00dd4cff2757
Publikováno v:
iScience, Vol 26, Iss 6, Pp 106930- (2023)
Summary: Double-stranded RNA (dsRNA) regulates gene expression in a sequence-dependent manner. In Caenorhabditis elegans, dsRNA spreads through the body and leads to systemic RNA silencing. Although several genes involved in systemic RNAi have been g
Externí odkaz:
https://doaj.org/article/4274b158f7e842b7a90539c33c275575
Autor:
Yuji Suehiro, Sawako Yoshina, Tomoko Motohashi, Satoru Iwata, Katsufumi Dejima, Shohei Mitani
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract With the development of massive parallel sequencing technology, it has become easier to establish new model organisms that are ideally suited to the specific biological phenomena of interest. Considering the history of research using classic
Externí odkaz:
https://doaj.org/article/301ba8ccca06423d805b46c450f7433e
Autor:
Katsufumi Dejima, Sayaka Hori, Satoru Iwata, Yuji Suehiro, Sawako Yoshina, Tomoko Motohashi, Shohei Mitani
Publikováno v:
Cell Reports, Vol 22, Iss 1, Pp 232-241 (2018)
Summary: Balancer chromosomes are critical tools for genetic research. In C. elegans, reciprocal translocations that lead to aneuploidy have been widely used to maintain lethal and sterile mutations in stable stocks. Here, we generated a set of aneup
Externí odkaz:
https://doaj.org/article/9bef06a53643476caa2e1e182ecb4fe0
Autor:
Katsufumi, Dejima, Shohei, Mitani
Publikováno v:
microPublication biology. 2022
In some situations, researchers may want to evaluate whether mutants of the Million Mutation Project (Thompson et al. 2013) show the intended phenotype or not. To utilize the strains, it is required to outcross with other strain to remove background
Autor:
Daisuke Murata, Ayako Matsuda, Shohei Mitani, Karen L Abbott, Kazuya Nomura, Marika Rikitake, Katsufumi Dejima, Kazuko H. Nomura
Publikováno v:
The Journal of Biochemistry. 168:589-602
Stem cells divide and undergo self-renewal depending on the signals received from the stem cell niche. This phenomenon is indispensable to maintain tissues and organs in individuals. However, not all the molecular factors and mechanisms of self-renew
Autor:
Katsufumi Dejima, Satoru Iwata, Yuji Suehiro, Sawako Yoshina, Shohei Mitani, Tomoko Motohashi
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports
Scientific Reports
With the development of massive parallel sequencing technology, it has become easier to establish new model organisms that are ideally suited to the specific biological phenomena of interest. Considering the history of research using classical model
Autor:
Hiroshi Kitagawa, Eri Yanagita, Ai Kano, Kazuya Nomura, Yukiko Watamoto, Kazuko H. Nomura, Marika Rikitake, Katsufumi Dejima, Mai Tou, Shohei Mitani, Tomomi Izumikawa, Nanako Kanaki, Daisuke Murata
Publikováno v:
Journal of Biological Chemistry. 291:23294-23304
Chondroitin sulfate (CS)/chondroitin (Chn) chains are indispensable for embryonic cell division and cytokinesis in the early developmental stages in Caenorhabditis elegans and mice, whereas heparan sulfate (HS) is essential for axon guidance during n
Autor:
Takashi Ohkura, Ayako Matsuda, Kazuya Nomura, Daisuke Murata, Katsufumi Dejima, Sawako Yoshina, Nanako Kanaki, Kazuko H. Nomura, Shohei Mitani, Keiko Gengyo-Ando
Publikováno v:
Glycobiology. 29(2)
N-linked glycosylation of proteins is the most common post-translational modification of proteins. The enzyme UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase (DPAGT1) catalyses the first step of N-glycosylation, and D
Autor:
Masahiko Takemura, Akiko Kinoshita-Toyoda, Hiroshi Nakato, Katsufumi Dejima, Hidenao Toyoda, Yoshiki Hayashi, Jesse Peterson, Eriko Nakato
Publikováno v:
Journal of Biological Chemistry. 288:34384-34393
During the biosynthesis of heparan sulfate (HS), glucuronyl C5-epimerase (Hsepi) catalyzes C5-epimerization of glucuronic acid (GlcA), converting it to iduronic acid (IdoA). Because HS 2-O-sulfotransferase (Hs2st) shows a strong substrate preference