Detection and quantification of antibody to SARS-CoV-2 receptor binding domain provides enhanced sensitivity, specificity and utility

Autor: Tedder, RS, Parker, E, Sureda-Vives, M, Fernandez, N, Randell, P, Marchesin, F, Katsanovskaja, K, Harvey, R, Lilley, A, Harris, BHL, Zuhair, M, Fertleman, M, Ijaz, S, Dicks, S, Short, C-E, Quinlan, R, Taylor, GP, McKay, P, Hu, K, Rosa, A, Roustan, C, Zuckerman, M, El Bouzidi, K, Cooke, G, Flower, B, Moshe, M, Elliott, P, Spencer, AJ, Lambe, T, Gilbert, SC, Kingston, H, Baillie, JK, Openshaw, P, Semple, M, Cherepanov, P, McLure, M

Background: Accurate and sensitive detection of antibody to SARS-CoV-2 remains an essential component of the pandemic response. Measuring antibody that predicts neutralising activity and the vaccine response is an absolute requirement for laboratory-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1032::caf1881ddb54b4f57de66dfa71dc8823
http://hdl.handle.net/10044/1/99352

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Mapping of SARS-CoV-2 IgM and IgG in gingival crevicular fluid: Antibody dynamics and linkage to severity of COVID-19 in hospital inpatients.

Autor: Ijaz S; Blood Borne Virus Unit, Reference Department, UK Health Security Agency, 61 Colindale Avenue, London NW9 5EQ, UK. Electronic address: samreen.ijaz@phe.gov.uk., Dicks S; Blood Borne Virus Unit, Reference Department, UK Health Security Agency, 61 Colindale Avenue, London NW9 5EQ, UK; NHS Blood and Transplant, London, UK., Jegatheesan K; Blood Borne Virus Unit, Reference Department, UK Health Security Agency, 61 Colindale Avenue, London NW9 5EQ, UK; NHS Blood and Transplant, London, UK., Parker E; Department of Infectious Disease, Imperial College London, London, UK., Katsanovskaja K; Department of Infectious Disease, Imperial College London, London, UK., Vink E; Medical Research Council, University of Glasgow Centre for Virus Research, Glasgow, UK., McClure MO; Department of Infectious Disease, Imperial College London, London, UK., Shute J; Blood Borne Virus Unit, Reference Department, UK Health Security Agency, 61 Colindale Avenue, London NW9 5EQ, UK., Hope J; Chromatin Structure and Mobile DNA Laboratory, The Francis Crick Institute, London, UK., Cook N; Chromatin Structure and Mobile DNA Laboratory, The Francis Crick Institute, London, UK., Cherepanov P; Department of Infectious Disease, Imperial College London, London, UK; Chromatin Structure and Mobile DNA Laboratory, The Francis Crick Institute, London, UK., Turtle L; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK; Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK., Paxton WA; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK; NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, Department of Clinical Infection, Microbiology and Immunology, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK., Pollakis G; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK; NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, Department of Clinical Infection, Microbiology and Immunology, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK., Ho A; Medical Research Council, University of Glasgow Centre for Virus Research, Glasgow, UK., Openshaw PJM; National Heart & Lung Institute, Imperial College, London, UK., Baillie JK; Roslin Institute, University of Edinburgh, Edinburgh, UK., Semple MG; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK; Department of Respiratory Medicine, Alder Hey Children's Hospital, Liverpool, UK., Tedder RS; Department of Infectious Disease, Imperial College London, London, UK.

Publikováno v: The Journal of infection [J Infect] 2022 Aug; Vol. 85 (2), pp. 152-160. Date of Electronic Publication: 2022 Jun 03.