Zobrazeno 1 - 10 of 14 pro vyhledávání: '"Katrine Zeeberg"'
1
Akademický článek
TGFβ Signaling Increases Net Acid Extrusion, Proliferation and Invasion in Panc-1 Pancreatic Cancer Cells: SMAD4 Dependence and Link to Merlin/NF2 Signaling
Autor: Raj R. Malinda, Katrine Zeeberg, Patricia C. Sharku, Mette Q. Ludwig, Lotte B. Pedersen, Søren T. Christensen, Stine F. Pedersen
Publikováno v: Frontiers in Oncology, Vol 10 (2020)
Pancreatic ductal adenocarcinoma (PDAC) is a major cause of cancer-related death, with a 5-year survival of
Externí odkaz: https://doaj.org/article/7908db2c173946f0a28b4c452f320bb5
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2
Akademický článek
A Novel NHE1-Centered Signaling Cassette Drives Epidermal Growth Factor Receptor–Dependent Pancreatic Tumor Metastasis and Is a Target for Combination Therapy
Autor: Rosa Angela Cardone, Maria Raffaella Greco, Katrine Zeeberg, Angela Zaccagnino, Mara Saccomano, Antonia Bellizzi, Philipp Bruns, Marta Menga, Christian Pilarsky, Albrecht Schwab, Frauke Alves, Holger Kalthoff, Valeria Casavola, Stephan Joel Reshkin
Publikováno v: Neoplasia: An International Journal for Oncology Research, Vol 17, Iss 2, Pp 155-166 (2015)
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers principally because of early invasion and metastasis. The epidermal growth factor receptor (EGFR) is essential for PDAC development even in the presence of Kras, but its inhibi
Externí odkaz: https://doaj.org/article/3cb735e04e994897beba64f72621b1dc
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4
Cancer Associated Fibroblast (CAF) Regulation of PDAC Parenchymal (CPC) and CSC Phenotypes Is Modulated by ECM Composition
Autor: Stefania Cannone, Maria Raffaella Greco, Tiago M. A. Carvalho, Helene Guizouarn, Olivier Soriani, Daria Di Molfetta, Richard Tomasini, Katrine Zeeberg, Stephan Joel Reshkin, Rosa Angela Cardone
Publikováno v: Cancers
Cancers, 2022, 14 (15), ⟨10.3390/cancers14153737⟩
Cancers; Volume 14; Issue 15; Pages: 3737
Simple Summary Here, we demonstrate for the first time that ECM composition cooperates with CAFs to jointly regulate/modulate the highly dynamic interactions between the CPC and CSC cell lines and establish a continuum between tumor initiation and pr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da5e4d890d796fd1c1695a972c44b0bf
https://pubmed.ncbi.nlm.nih.gov/35954400
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5
Cancer Associated Fibroblast (CAF) regulation of PDAC parenchymal (CPC) and CSC phenotypes is modulated by ECM composition
Autor: Stefania Cannone, Maria Rafaella Greco, Hélène Guizouarn, Olivier Soriani, Richard Tomasini, Valeria Casavola, Katrine Zeeberg, Stephan Joel Reshkin, Rosa Angela Cardone
Background Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest of all cancers having one of the lowest five-year survival rates. One of its hallmarks is a dense desmoplastic stroma consisting in the abnormal accumulation of extracellular
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fa0f3f7bac7797f89d958bc923590063
https://doi.org/10.21203/rs.2.13193/v2
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7
Extracellular Matrix composition modulates PDAC parenchymal and stem cell plasticity and behavior through the secretome
Autor: Elisa Dalla Pozza, Katrine Zeeberg, Ilaria Dando, Stefania Forciniti, Maria Mastrodonato, Maria Raffaella Greco, Stefania Cannone, Stephan J. Reshkin, Giulia Biondani, Valeria Casavola, Marta Palmieri, Rosa Angela Cardone
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers. Its aggressiveness is driven by an intense fibrotic desmoplastic reaction in which the increasingly collagen I-rich extracellular matrix (ECM) and several cell types, includin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9b1aefdc26d38d2afebe3abc412b634
http://hdl.handle.net/11562/978842
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8
A Novel NHE1-Centered Signaling Cassette Drives Epidermal Growth Factor Receptor–Dependent Pancreatic Tumor Metastasis and Is a Target for Combination Therapy
Autor: Frauke Alves, Angela Zaccagnino, Antonia Bellizzi, Maria Raffaella Greco, Rosa Angela Cardone, Stephan J. Reshkin, Philipp Bruns, Albrecht Schwab, Valeria Casavola, Holger Kalthoff, Mara Saccomano, Christian Pilarsky, Marta Menga, Katrine Zeeberg
Publikováno v: Neoplasia: An International Journal for Oncology Research, Vol 17, Iss 2, Pp 155-166 (2015)
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers principally because of early invasion and metastasis. The epidermal growth factor receptor (EGFR) is essential for PDAC development even in the presence of Kras, but its inhibi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c8e899a0f9ac95e30c37f951c023689
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9
The scaffolding protein NHERF1 sensitizes EGFR-dependent tumor growth, motility and invadopodia function to gefitinib treatment in breast cancer cells
Autor: Katrine Zeeberg, Stephan J. Reshkin, Rosa Rubino, Stefania Forciniti, Angelo Paradiso, Rosa Angela Cardone, Antonia Bellizzi, Maria Raffaella Greco
Publikováno v: International Journal of Oncology. 46:1214-1224
Triple negative breast cancer (TNBC) patients cannot be treated with endocrine therapy or targeted therapies due to lack of related receptors. These patients overexpress the epidermal growth factor receptor (EGFR), but are resistant to tyrosine kinas
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feeaf4fe0d2bf6939878ffae00833bc5
https://doi.org/10.3892/ijo.2014.2805
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