Circulating cell‐free HPV DNA is a strong marker for disease severity in cervical cancer

Autor: Sara Bønløkke, Torben Steiniche, Boe Sandahl Sorensen, Gitte‐Bettina Nyvang, Jacob Christian Lindegaard, Jan Blaakær, Jesper Bertelsen, Katrine Fuglsang, Mikael Lenz Strube, Suzan Lenz, Magnus Stougaard

Publikováno v: Molecular Oncology, Vol 18, Iss 5, Pp 1231-1244 (2024)

For cervical cancer (CC), circulating cell‐free HPV DNA (ccfHPV) may establish disease severity. Furthermore, HPV integration has been correlated to viral load and survival. In this study, pre‐treatment plasma from 139 CC cases (50 primary surger

Externí odkaz: https://doaj.org/article/ff0349f899b14681a67f3aa4b23c11ad

Detection of high-risk human papillomavirus DNA in tissue from primary cervical cancer tumor, pelvic lymph nodes and recurrent disease

Autor: Katrine Fuglsang, Jan Blaakaer, Lone Kjeld Petersen, Else Mejlgaard, Anne Hammer, Torben Steiniche

Publikováno v: Papillomavirus Research, Vol 7, Iss , Pp 15-20 (2019)

Objectives: The present study investigated Human Papillomavirus (HPV) DNA genotyping in primary tumor, pelvic lymph nodes (PLN) and recurrence in early-stage cervical cancer patients. Methods: We conducted a hospital-based case-control study. From 20

Externí odkaz: https://doaj.org/article/70b80342e8a8428db43901a2ae1aa6ea

A federated approach to identify women with early-stage cervical cancer at low risk of lymph node metastases

Autor: Hans H.B. Wenzel, Anna N. Hardie, Arturo Moncada-Torres, Claus K. Høgdall, Ruud L.M. Bekkers, Henrik Falconer, Pernille T. Jensen, Hans W. Nijman, Maaike A. van der Aa, Frank Martin, Anna J. van Gestel, Valery E.P.P. Lemmens, Pernilla Dahm-Kähler, Emilia Alfonzo, Jan Persson, Linnea Ekdahl, Sahar Salehi, Ligita P. Frøding, Algirdas Markauskas, Katrine Fuglsang, Tine H. Schnack

Publikováno v: Wenzel, H H B, Hardie, A N, Moncada-Torres, A, Høgdall, C K, Bekkers, R L M, Falconer, H, Jensen, P T, Nijman, H W, van der Aa, M A, Martin, F, van Gestel, A J, Lemmens, V E P P, Dahm-Kähler, P, Alfonzo, E, Persson, J, Ekdahl, L, Salehi, S, Frøding, L P, Markauskas, A, Fuglsang, K & Schnack, T H 2023, ' A federated approach to identify women with early-stage cervical cancer at low risk of lymph node metastases ', European Journal of Cancer, vol. 185, pp. 61-68 . https://doi.org/10.1016/j.ejca.2023.02.021
European Journal of Cancer, 185, 61-68. Elsevier Ltd.

OBJECTIVE: Lymph node metastases (pN+) in presumed early-stage cervical cancer negatively impact prognosis. Using federated learning, we aimed to develop a tool to identify a group of women at low risk of pN+, to guide the shared decision-making proc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f3a5ae0ef636bab7530ed4548aab730
https://pure.au.dk/portal/da/publications/a-federated-approach-to-identify-women-with-earlystage-cervical-cancer-at-low-risk-of-lymph-node-metastases(53222236-a198-489c-a4ac-d5c1c2947e6d).html

SENTIREC - The sentinel node mapping in women with cervical cancer study

Autor: Sara Elisabeth Sponholtz, Nicole P.M. Ezendam, Belle H. de Rooij, Erik Parner, Ole Mogensen, Malene Grubbe Hildebrandt, Doris Schledermann, Algirdas Markauskas, Ligita Paskeviciute Frøding, Katrine Fuglsang, Sarah Marie Bjørnholt, Pernille Tine Jensen

Publikováno v: Sponholtz, S E, Ezendam, N P M, de Rooij, B H, Parner, E, Mogensen, O, Hildebrandt, M G, Schledermann, D, Markauskas, A, Frøding, L P, Fuglsang, K, Bjørnholt, S M & Jensen, P T 2022, ' SENTIREC – The sentinel node mapping in women with cervical cancer study – Patient-reported early lymphedema and its impact on quality of life ', Gynecologic Oncology, vol. 164, no. 3, pp. 463-472 . https://doi.org/10.1016/j.ygyno.2021.12.024
Gynecologic Oncology, 164(3), 463-472. Academic Press Inc.

Objective: To evaluate patient-reported incidence and severity of early lymphedema and its impact on quality of life (QoL) after sentinel lymph node (SLN) mapping only and after SLN and pelvic lymphadenectomy (PL) in women undergoing surgery for earl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::514686ef023e0b140f4e8947415e878d
https://doi.org/10.1016/j.ygyno.2021.12.024

Sentinel lymph node mapping in early-stage cervical cancer – A national prospective multicenter study (SENTIREC trial)

Autor: Erik T. Parner, Katrine Fuglsang, Sarah Marie Bjørnholt, Mie Holm Vilstrup, Pernille Tine Jensen, Doris Schledermann, Sara Elisabeth Sponholtz, Algirdas Markauskas, Ole Mogensen, Ligita Paskeviciute Frøding, Malene Hildebrandt

Publikováno v: Sponholtz, S E, Mogensen, O, Hildebrandt, M G, Schledermann, D, Parner, E, Markauskas, A, Frøding, L P, Fuglsang, K, Vilstrup, M H, Bjørnholt, S M & Jensen, P T 2021, ' Sentinel lymph node mapping in early-stage cervical cancer-A national prospective multicenter study (SENTIREC trial) ', Gynecologic Oncology, vol. 162, no. 3, pp. 546-554 . https://doi.org/10.1016/j.ygyno.2021.06.018
Sponholtz, S E, Mogensen, O, Hildebrandt, M G, Schledermann, D E, Parner, E, Markauskas, A, Frøding, L, Fuglsang, K, Vilstrup, M H, Bjørnholt, S & Jensen, P 2021, ' Sentinel lymph node mapping in early-stage cervical cancer – a national prospective multicenter study (sentirec trial) ', International Journal of Gynecological Cancer, vol. 31, no. Suppl. 4, A11 . https://doi.org/10.1136/ijgc-2021-igcs.18
Sponholtz, S E, Mogensen, O, Hildebrandt, M G, Schledermann, D, Parner, E, Markauskas, A, Frøding, L P, Fuglsang, K, Vilstrup, M H, Bjørnholt, S M & Jensen, P T 2021, ' Sentinel lymph node mapping in early-stage cervical cancer – A national prospective multicenter study (SENTIREC trial) ', Gynecologic Oncology, vol. 162, no. 3, pp. 546-554 . https://doi.org/10.1016/j.ygyno.2021.06.018

OBJECTIVES: Sentinel lymph node (SLN) mapping may replace staging radical pelvic lymphadenectomy in women with early-stage cervical cancer. In a national multicenter setting, we evaluated SLN mapping in women with early-stage cervical cancer and inve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebf16c63c41c43162cc53263528beb97
https://doi.org/10.1016/j.ygyno.2021.06.018