Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Katrina S. Hofstetter"'
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
Congenital ocular malformations originate from defective morphogenesis during early eye development and cause 25% of childhood blindness. Formation of the eye is a multi-step, dynamic process; it involves evagination of the optic vesicle, followed by
Externí odkaz:
https://doaj.org/article/e1d90dca5ac049e39c0b62011e9d9a96
Autor:
Hanzhi Zhang, Yaping Pan, Liya Hu, M. Ashley Hudson, Katrina S. Hofstetter, Zhichun Xu, Mingqiang Rong, Zhao Wang, B. V. Venkataram Prasad, Steve W. Lockless, Wah Chiu, Ming Zhou
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
TrkH is a bacterial ion channel that is regulated by nucleotides and its associated protein TrkA. Here the authors present ADP and ATP bound TrkH-TrkA structures, which reveal the mechanism for the transmission of nucleotide-induced conformational ch
Externí odkaz:
https://doaj.org/article/8f5a444b3e2548a29ca6d697a5a934a9
Autor:
Yaping Pan, M. Ashley Hudson, Mingqiang Rong, Zhichun Xu, Hanzhi Zhang, Wah Chiu, Steve W. Lockless, B. V. Venkataram Prasad, Liya Hu, Zhao Wang, Katrina S. Hofstetter, Ming Zhou
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Nature Communications
Nature Communications
TrkH is a bacterial ion channel implicated in K+ uptake and pH regulation. TrkH assembles with its regulatory protein, TrkA, which closes the channel when bound to ADP and opens it when bound to ATP. However, it is unknown how nucleotides control the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35464b01ca4be6094ebfb9a122b292d6
https://doi.org/10.1038/s41467-019-14240-9
https://doi.org/10.1038/s41467-019-14240-9