Výsledky vyhledávání - "Katrina Mayol"

Quantitative PCR–Based Method to Assess Cell-Free DNA Quality, Adjust Input Mass, and Improve Next-Generation Sequencing Assay Performance

Autor: Seng Lor Saelee, Alexander F. Lovejoy, Bernd Hinzmann, Katrina Mayol, Samantha Huynh, Amy Harrell, Josh Lefkowitz, Niharika Deodhar, Gladys Garcia-Montoya, Stephanie J. Yaung, Daniel M. Klass

Publikováno v: The Journal of Molecular Diagnostics. 24:566-575

Cell-free (cf)DNA-based testing has undergone increasingly wide adoption, including assays for the detection of circulating tumor DNA. Due to nucleosome protection, cfDNA has a distinctive fragment size of 160 to 180 bp. However, cfDNA can be contami

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f45f83a9e84d89629d0efe4c1a262850
https://doi.org/10.1016/j.jmoldx.2022.02.005

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Abstract 4574: Detection of minimal residual disease from less than one cell equivalent in liquid biopsy samples using the AVENIO ctDNA Surveillance Kit

Autor: Seng Lor Saelee, Katrina Mayol, Abraham Munoz, Paul W. Shi, Alex Lovejoy, Amrita Pati, Vera Rapoport, Janet Jin, Dan Klass

Publikováno v: Cancer Research. 78:4574-4574

A key technical challenge in oncology is the detection of minimal residual disease (MRD, the presence of residual tumor in a subject post-treatment). Recent studies have shown poor prognostic outcomes for research subjects with ultra-low residual tum

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4fe6a1d9bc8b0904441ca0d844c346c5
https://doi.org/10.1158/1538-7445.am2018-4574

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Correlation of pre- and post-induction plasma mutant allele fraction with progression-free survival (PFS) in STEAM, a prospective, randomized, multicenter study in metastatic colorectal cancer (mCRC)

Autor: John F. Palma, Christoph Mancao, Alan Nicholas, Carolyn Williams, May Yau, Nasiema Wingate-Pearse, Lijing Yao, Nicolas Sommer, Monica Pimentel, David Zhang, Johanna C. Bendell, John Lee, Abraham Munoz, Stephanie J. Yaung, Katrina Mayol, Herbert Hurwitz, Alexander F. Lovejoy, Ulrich Peter Rohr

Publikováno v: Journal of Clinical Oncology. 35:e15118-e15118

e15118 Background: STEAM (NCT01765582) evaluated the efficacy and safety of concurrent (c) and sequential (s) FOLFOXIRI-bevacizumab (BEV) versus FOLFOX-BEV for first-line treatment of mCRC. Methods: The AVENIO ctDNA Expanded Kit (Research Use Only) w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4691d5d12c0b622088af057a4d2f5c04
https://doi.org/10.1200/jco.2017.35.15_suppl.e15118

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Evaluation of clinical outcomes by analysis of mutations in tumor tissue and circulating plasma DNA using next-generation sequencing (NGS) from STEAM, a prospective, randomized, multicenter study in metastatic colorectal cancer (mCRC)

Autor: Ulrich Peter Rohr, May Yau, Nasiema Wingate-Pearse, Johanna C. Bendell, Lijing Yao, David Zhang, Nicolas Sommer, Alexander F. Lovejoy, Monica Pimentel, Abraham Munoz, Alan Nicholas, John F. Palma, John Lee, Carolyn Williams, Stephanie J. Yaung, Katrina Mayol, Herbert Hurwitz, Christoph Mancao

Publikováno v: Journal of Clinical Oncology. 35:11510-11510

11510 Background: STEAM (NCT01765582) assessed the efficacy and safety of concurrent (c) and sequential (s) FOLFOXIRI-bevacizumab (BEV) vs FOLFOX-BEV for first-line treatment of mCRC. Methods: The AVENIO ctDNA Expanded Kit (Research Use Only) was use

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5149e60f0ccce1196a000da00363cba7
https://doi.org/10.1200/jco.2017.35.15_suppl.11510

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