Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Katrina L. Clines"'
Publikováno v:
Journal of Bone Oncology, Vol 45, Iss , Pp 100563- (2024)
Externí odkaz:
https://doaj.org/article/aad3962b14264a62bfb7fec90cff771d
Autor:
Katrina L. Clines, Gregory A. Clines
Publikováno v:
Translational Oncology, Vol 11, Iss 4, Pp 873-882 (2018)
Bone metastasis is a complication of advanced breast and prostate cancer. Tumor-secreted Dickkopf homolog 1 (DKK1), an inhibitor of canonical Wnt signaling and osteoblast differentiation, was proposed to regulate the osteoblastic response to metastat
Externí odkaz:
https://doaj.org/article/31575cac9c6e4d1d8644e75809e958ed
Autor:
Katrina L Clines, Charlotte A Cialek, Mark A Cooks, Marian A Esvelt, Gregory A. Clines, Henry H Moon
Publikováno v:
Endocrinology. 160:1786-1796
Bone metastasis is a painful complication of advanced prostate cancer. Endothelin-1 is a tumor-secreted factor that plays a central role in osteoblast activation and the osteosclerotic response of prostate cancer metastatic to bone. Antagonists that
Osteoblasts Generate Testosterone From DHEA and Activate Androgen Signaling in Prostate Cancer Cells
Autor:
Charles R. Farber, Katrina L Clines, Henry H Moon, Emily Farber, Gregory A. Clines, Richard J. Auchus, Patrick O’Day, Basel M. Al-Barghouthi
Publikováno v:
J Bone Miner Res
Bone metastasis is a complication of prostate cancer in up to 90% of men afflicted with advanced disease. Therapies that reduce androgen exposure remain at the forefront of treatment. However, most prostate cancers transition to a state whereby reduc
Autor:
null Henry H. Moon, null Katrina L. Clines, null Patrick J. O'Day, null Basel M. Al‐Barghouthi, null Emily A. Farber, null Charles R. Farber, null Richard J. Auchus, null Gregory A. Clines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d35a47b2e367051d59be9356ef9d2acb
https://doi.org/10.1002/jbmr.4313/v5/response1
https://doi.org/10.1002/jbmr.4313/v5/response1
Autor:
Charles R. Farber, Basel M. Al-Barghouthi, Richard J. Auchus, Gregory A. Clines, Patrick O’Day, Emily Farber, Henry H Moon, Katrina L. Clines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04dce8ea5619e8a2d8c1f4ea2097e836
https://doi.org/10.1002/jbmr.4313/v2/response1
https://doi.org/10.1002/jbmr.4313/v2/response1
Autor:
Gregory A. Clines, Katrina L Clines, Charles R. Farber, Patrick O’Day, Henry H Moon, Richard J. Auchus
Publikováno v:
Journal of the Endocrine Society
Androgens have complex effects on the skeleton. Besides gonadal testosterone (T), the adrenal produces the androgen precursor dehydroepiandrosterone (DHEA), using 3β- and 17β-hydroxysteroid dehydrogenases (3βHSD & 17βHSD) to convert to T in targe
Autor:
Eleanor C. Smith, Gregory A. Clines, Katrina L Clines, Russell S. Taichman, Alexandra Calinescu, Rebecca Tagett, Nicholas J. Szerlip, Catherine Van Poznak, Henry H Moon
Publikováno v:
Neurosurgery
Background Thirty per cent of cancer patients develop spine metastases with a substantial number leading to spinal cord compression and neurological deficits. Many demonstrate a propensity toward metastasis to the posterior third of the vertebral bod
Autor:
Zachary T. Freeman, Melissa C. Dyson, Katrina L Clines, Jack R. Harkema, Alexander T. Pearson, Marian A Esvelt, Gregory T. Clines, Mark J. Hoenerhoff
Publikováno v:
Toxicol Pathol
Zibotentan, an endothelin-A receptor antagonist, has been used in the treatment of various cardiovascular disorders and neoplasia. Castrated athymic nude mice receiving zibotentan for a preclinical xenograft efficacy study experienced weight loss, ga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca1fa4e6502765bd0cc5ff47e5e46f35
https://europepmc.org/articles/PMC7357205/
https://europepmc.org/articles/PMC7357205/
Autor:
Russell S. Taichman, Moon H, Gregory A. Clines, Alexandra Calinescu, Katrina L Clines, Van Poznak C, Nicholas J. Szerlip
The dura mater, the outer layer of the protective meninges, lies adjacent to the skull and vertebral bones, and, at specific sites, in direct contact with the bone marrow (BM). During development, the dura regulates morphogenesis in the CNS and bone,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45bb42bcb66a0d4bfc5e88ef772757e5
https://europepmc.org/articles/PMC5693052/
https://europepmc.org/articles/PMC5693052/