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pro vyhledávání: '"Katrina K. Treloar"'
Autor:
Katrina K Treloar, Matthew J Simpson
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e67389 (2013)
Quantitative imaging methods to analyze cell migration assays are not standardized. Here we present a suite of two-dimensional barrier assays describing the collective spreading of an initially-confined population of 3T3 fibroblast cells. To quantify
Externí odkaz:
https://doaj.org/article/e7556b89de664c1b9b136379556da9ea
Publikováno v:
Journal of Theoretical Biology. 356:71-84
Cells respond to various biochemical and physical cues during wound-healing and tumour progression. in vitro assays used to study these processes are typically conducted in one particular geometry and it is unclear how the assay geometry affects the
Autor:
Ruth E. Baker, Katrina K. Treloar, D. L. Sean McElwain, Matthew J. Simpson, Benjamin J. Binder
Publikováno v:
Scientific Reports
Spreading cell fronts are essential features of development, repair and disease processes. Many mathematical models used to describe the motion of cell fronts, such as Fisher's equation, invoke a mean–field assumption which implies that there is no
Autor:
Parvathi Haridas, David I. Leavesley, D. L. Sean McElwain, Katrina K. Treloar, Matthew J. Simpson, Kerry J. Manton, Ruth E. Baker
Publikováno v:
BMC Systems Biology
Background The expansion of cell colonies is driven by a delicate balance of several mechanisms including cell motility, cell–to–cell adhesion and cell proliferation. New approaches that can be used to independently identify and quantify the role
Autor:
D. L. Sean McElwain, Katrina K. Treloar, Benjamin J. Binder, Benjamin K. Wood, Matthew J. Simpson, Parvathi Haridas, Ruth E. Baker
Publikováno v:
Bulletin of mathematical biology. 75(5)
Standard differential equation-based models of collective cell behaviour, such as the logistic growth model, invoke a mean-field assumption which is equivalent to assuming that individuals within the population interact with each other in proportion
Publikováno v:
Physical review. E, Statistical, nonlinear, and soft matter physics. 84(6 Pt 1)
Velocity-jump processes are discrete random-walk models that have many applications including the study of biological and ecological collective motion. In particular, velocity-jump models are often used to represent a type of persistent motion, known
Autor:
Matthew J. Simpson, Katrina K. Treloar
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e67389 (2013)
PLoS ONE
PLoS ONE
Quantitative imaging methods to analyze cell migration assays are not standardized. Here we present a suite of two-dimensional barrier assays describing the collective spreading of an initially-confined population of 3T3 fibroblast cells. To quantify
Publikováno v:
Journal of Physics A: Mathematical and Theoretical. 46:015003
Cell invasion involves a population of cells that migrate along a substrate and proliferate to a carrying capacity density. These two processes, combined, lead to invasion fronts that move into unoccupied tissues. Traditional modelling approaches bas