Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Katrina H. Jensen"'
Publikováno v:
Biochemistry. 56:219-227
Collagen prolyl 4-hydroxylases (CP4Hs) catalyze a prevalent posttranslational modification, the hydroxylation of (2S)-proline residues in protocollagen strands. The ensuing (2S,4R)-4-hydroxyproline residues are necessary for the conformational stabil
Publikováno v:
Organic Letters. 14:4074-4077
A palladium-catalyzed enantio- and diastereoselective synthesis of pyrrolidine derivatives is described. Initial intramolecular nucleopalladation of the tethered protected amine forms the pyrrolidine moiety and a quinone methide intermediate. A secon
Autor:
Katrina H. Jensen, Matthew S. Sigman
Publikováno v:
The Journal of Organic Chemistry. 75:7194-7201
A modular catalyst structure was applied to evaluate the effects of catalyst acidity in a hydrogen bond-catalyzed hetero Diels-Alder reaction. Linear free energy relationships between catalyst acidity and both rate and enantioselectivity were observe
Autor:
Matthew S. Sigman, Katrina H. Jensen
Publikováno v:
Angewandte Chemie International Edition. 46:4748-4750
Autor:
Katrina H. Jensen, Matthew S. Sigman
Publikováno v:
Angewandte Chemie. 119:4832-4834
Publikováno v:
ChemInform. 43
A palladium-catalyzed enantio- and diastereoselective synthesis of pyrrolidine derivatives is described. Initial intramolecular nucleopalladation of the tethered protected amine forms the pyrrolidine moiety and a quinone methide intermediate. A secon
Publikováno v:
Journal of the American Chemical Society. 132(49)
The mechanism of an enantioselective palladium-catalyzed alkene difunctionalization reaction has been investigated. Kinetic analysis provides evidence of turnover-limiting attack of a proposed quinone methide intermediate with MeOH and suggests that
Publikováno v:
ChemInform. 41
A sequential intramolecular−intermolecular enantioselective alkene difunctionalization reaction has been developed which is thought to proceed through Pd-catalyzed quinone methide formation. The synthesis of new chiral heterocyclic compounds with a
A sequential intramolecular−intermolecular enantioselective alkene difunctionalization reaction has been developed which is thought to proceed through Pd-catalyzed quinone methide formation. The synthesis of new chiral heterocyclic compounds with a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::097c9a843f999d28761e85437eb5ed21
https://europepmc.org/articles/PMC2792916/
https://europepmc.org/articles/PMC2792916/
Autor:
Katrina H. Jensen, Matthew S. Sigman
Publikováno v:
ChemInform. 40
Alkene difunctionalization, the addition of two functional groups across a double bond, exemplifies a class of reactions with significant synthetic potential. This emerging area examines recent developments of palladium-catalyzed difunctionalization