Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Katrina H. Andrews"'
Autor:
Heta Desai, Katrina H. Andrews, Kristina V. Bergersen, Samuel Ofori, Fengchao Yu, Flowreen Shikwana, Mark A. Arbing, Lisa M. Boatner, Miranda Villanueva, Nicholas Ung, Elaine F. Reed, Alexey I. Nesvizhskii, Keriann M. Backus
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-24 (2024)
Abstract Cancer genomes are rife with genetic variants; one key outcome of this variation is widespread gain-of-cysteine mutations. These acquired cysteines can be both driver mutations and sites targeted by precision therapies. However, despite thei
Externí odkaz:
https://doaj.org/article/8497dd94edd44189a1d7fe0683afc5b4
Autor:
Katrina H. Andrews, Marco Catalano, Federica Mazzieri, Dario Neri, Jörg Scheuermann, James Clayton, Mustafa Moroglu, Martina Bigatti, Stuart J. Conway, Petra Balbi
Publikováno v:
ChemMedChem, 15 (18)
DNA‐encoded chemical libraries (DECLs) are collections of chemical moieties individually coupled to distinctive DNA barcodes. Compounds can be displayed either at the end of a single DNA strand (i. e., single‐pharmacophore libraries) or at the ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb08b27f98e38bed5edab1f587664ce8
https://doi.org/10.1002/cmdc.202000528
https://doi.org/10.1002/cmdc.202000528
Autor:
Matthias Schiedel, Katrina H. Andrews, Corentine M.C. Laurin, Joseph P. Bluck, Stuart J. Conway, Prakriti Kalra, Panagis Filippakopoulos, James Clayton, Anthony K. N. Chan, Amy R. Scorah, Oleg Fedorov, Ester M. Hammond, Mustafa Moroglu, Kayla B. Vinh, William C. K. Pomerantz, Richard I. Cooper, Wilian A. Cortopassi, Pascal Heitel, Robert S. Paton, Anna Skwarska, Gabriella T. Perell, Kirsten E. Christensen, Larissa See, Hannah Bolland, Timothy P. C. Rooney, Sarah Picaud, Philip C. Biggin, Michael Brand
Publikováno v:
Journal of Medicinal Chemistry
CREBBP (CBP/KAT3A) and its paralogue EP300 (KAT3B) are lysine acetyltransferases (KATs) that are essential for human development. They each comprise 10 domains through which they interact with >400 proteins, making them important transcriptional co-a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2e5b7850f0b3a5289c8056a1b4a57d6
https://pubmed.ncbi.nlm.nih.gov/34255515
https://pubmed.ncbi.nlm.nih.gov/34255515