Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Katrina Grosfils"'
Publikováno v:
General Pharmacology: The Vascular System. 27:1041-1046
1. Caffeine did not affect by itself the amylase release, nor intracellular calcium concentration in rat pancreatic acini. 2. Concentration of caffeine higher than 1 mM inhibited the amylase released in response to the muscarinic agonist carbamylchol
Publikováno v:
Journal of Cellular Physiology. 161:243-248
Rat submandibular glands were digested with crude collagenase, and the intracellular calcium concentration of the cellular suspension was measured using fura-2. In the absence of extracellular magnesium and calcium ([Ca2+]o), ATP had no effect; the r
Publikováno v:
General Pharmacology: The Vascular System. 25:1353-1359
1. Carbachol and thapsigargin both increased the intracellular calcium concentration in rat submandibular cells in the presence and in the absence of extracellular calcium. Depletion of intracellular calcium pools with thapsigargin prevented the resp
Publikováno v:
Biochemical and Biophysical Research Communications. 184:408-413
In intact rat pancreatic acini, the phospholipase A2 inhibitor mepacrine did not affect basal amylase release but dose-dependently inhibited the carbachol (IC50 65 microM) and CCK-8 (IC50 210 microM)-stimulated amylase release. In permeabilized acini
Publikováno v:
Biosensorsbioelectronics. 18(2-3)
A choline (CHO) biosensor based on the determination of H(2)O(2) generated at the electrode surface by the enzyme choline oxidase (CHOx) was developed. The biosensor consisted of CHOx retained onto a horseradish peroxidase (HRP) immobilized solid car
Autor:
Katrina Grosfils, Jean-Paul Dehaye, Mourad Metioui, Aida Marino, Antonio Gómez-Muñoz, Stéphanie Pochet
Publikováno v:
Cellular signalling. 15(1)
The muscarinic agonist carbachol stimulated phospholipase D (PLD) in rat submandibular gland (RSMG) ductal cells in a time and concentration-dependent manner. This effect was inhibited by chelation of extracellular calcium with ethylene glycol-bis(be
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 30(3 Pt 1)
Abstract We wished to determine whether the acute toxic effects of oxidized LDL are attenuated in aortas isolated from rats chronically treated with an angiotensin-converting enzyme (ACE) inhibitor. In aortic rings incubated with human oxidized LDL (
Study of nonspecific cation channel coupled to P2z purinergic receptors using an acid load technique
Autor:
Jean-Paul Dehaye, Mourad Metioui, Eduardo Alzola, M Lachish, Elie Kabre, Arie Moran, Naima Chaib, Aida Marino, Katrina Grosfils
Publikováno v:
The American journal of physiology. 271(6 Pt 1)
The intracellular pH (pHi) of rat submandibular cells was measured by 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein (BCECF). The cells recovered from ammonium (30 mM) prepulse to their resting pHi within 10 min. Ethylisopropylamiloride (EIPA), an i
Autor:
Philippe Unger, Jeanine Fontaine, Katrina Grosfils, Michel Staroukine, Dmitri Brékine, Guy Berkenboom
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 26(5)
Abstract To determine whether chronic angiotensin-converting enzyme (ACE) inhibition produces functional changes in the aorta of normotensive rats, four groups of rats were studied in parallel for 6 weeks. Group 1 orally received ramipril 10 mg/kg pe
Publikováno v:
General pharmacology. 25(3)
1. In intact rat pancreatic acini, 10 nM bombesin, 100 nM phorbol ester TPA and 10 mM fluoroaluminate increased amylase secretion 5-, 3- and 4-fold respectively. 2. Mepacrine dose-dependently inhibited the response to bombesin and fluoroaluminate but