Výsledky vyhledávání - "Katrina Carrion"

Akademický článek

The long non-coding HOTAIR is modulated by cyclic stretch and WNT/β-CATENIN in human aortic valve cells and is a novel repressor of calcification genes.

Autor: Katrina Carrion, Jeffrey Dyo, Vishal Patel, Roman Sasik, Salah A Mohamed, Gary Hardiman, Vishal Nigam

Publikováno v: PLoS ONE, Vol 9, Iss 5, p e96577 (2014)

Aortic valve calcification is a significant and serious clinical problem for which there are no effective medical treatments. Individuals born with bicuspid aortic valves, 1-2% of the population, are at the highest risk of developing aortic valve cal

Externí odkaz: https://doaj.org/article/d7b407c23f13477fbf07c68863d7b448

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miR-486 is modulated by stretch and increases ventricular growth

Autor: Majid Ghassemian, Rudolph Meili, Rebecca J Kameny, Luisa Lengenfelder, Juan C. del Álamo, Stephan Lange, Nancy D. Dalton, Marco Ricci, Kirk L. Peterson, Jeffery R. Fineman, Katrina Carrion, Emma Börgeson, Indroneal Banerjee, Vishal Nigam, Joy Lincoln, Louisa Habich, Ricardo Serrano

Publikováno v: JCI Insight
Lange, S, Banerjee, I, Carrion, K, Serrano, R, Habich, L, Kameny, R, Lengenfelder, L, Dalton, N, Meili, R, Börgeson, E, Peterson, K, Ricci, M, Lincoln, J, Ghassemian, M, Fineman, J, del Álamo, J C & Nigam, V 2019, ' MiR-486 is modulated by stretch and increases ventricular growth ', JCI Insight, vol. 4, no. 19, pp. 1-17 . https://doi.org/10.1172/jci.insight.125507

Perturbations in biomechanical stimuli during cardiac development contribute to congenital cardiac defects such as hypoplastic left heart syndrome (HLHS). This study sought to identify stretch-responsive pathways involved in cardiac development. miRN

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbd862bfa9ca50e243b07dda1e92a3f5
https://pubmed.ncbi.nlm.nih.gov/31513548

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The stretch responsive microRNA miR‐148a‐3p is a novel repressor of IKBKB , NF‐κB signaling, and inflammatory gene expression in human aortic valve cells

Autor: Vishal Patel, Thomas F. Gallegos, Andrew Hollands, Roman Sasik, Gary Hardiman, Victor Nizet, Salah A. Mohamed, Vishal Nigam, Charles C. King, Andrew Hinton, Katrina Carrion, Jeffrey Dyo, Emma Leire, Sanjay K. Nigam

Publikováno v: The FASEB Journal. 29:1859-1868

Bicuspid aortic valves calcify at a significantly higher rate than normal aortic valves, a process that involves increased inflammation. Because we have previously found that bicuspid aortic valve experience greater stretch, we investigated the poten

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53cc537f65283e75b0abdf7d223221ab
https://doi.org/10.1096/fj.14-257808

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Cyclic stretch of embryonic cardiomyocytes increases proliferation, growth, and expression while repressing Tgf-β signaling

Autor: Erik Willems, Seema S. Aceves, Gary Hardiman, Ricardo Serrano, Sean Lund, Jeffrey Dyo, Ju Chen, Mark Mercola, Taylor A. Doherty, Stephan Lange, Rudolph Meili, Indroneal Banerjee, Juan C. del Álamo, Roman Sasik, Vishal Nigam, Alexander C. Zambon, Katrina Carrion

Publikováno v: Banerjee, I, Carrion, K, Serrano, R, Dyo, J, Sasik, R, Lund, S, Willems, E, Aceves, S, Meili, R, Mercola, M, Chen, J, Zambon, A, Hardiman, G, Doherty, T A, Lange, S, del Álamo, J C & Nigam, V 2015, ' Cyclic stretch of embryonic cardiomyocytes increases proliferation, growth, and expression while repressing Tgf-β signaling ', Journal of Molecular and Cellular Cardiology, vol. 79, pp. 133-144 . https://doi.org/10.1016/j.yjmcc.2014.11.003

Perturbed biomechanical stimuli are thought to be critical for the pathogenesis of a number of congenital heart defects, including Hypoplastic Left Heart Syndrome (HLHS). While embryonic cardiomyocytes experience biomechanical stretch every heart bea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3afc1d2d98f7aa109b27ffea2e9c6dee
https://pure.au.dk/portal/da/publications/cyclic-stretch-of-embryonic-cardiomyocytes-increases-proliferation-growth-and-expression-while-repressing-tgf-signaling(3e1f3ef9-3dec-4764-8c84-1c18cc551046).html

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Abstract 284: Cyclic stretch of Embryonic Cardiomyocytes Increases Proliferation, Growth, and Expression While Repressing Tgf-β Signaling

Autor: Indroneal Banerjee, Katrina Carrion, Ricardo Serrano, Jeffrey Dyo, Sean Lund, Erik Willems, Seema Aceves, Rudolph Meili, Mark Mercola, Ju Chen, Alexander Zambon, Gary Hardiman, Taylor A Doherty, Juan C del Álamo, Vishal Nigam

Publikováno v: Circulation Research. 115

Rationale: Perturbed biomechanical stimuli are critical for the pathogenesis of a number of congenital heart defects, including Hypoplastic Left Heart Syndrome (HLHS). While ventricular cardiomyocytes experience biomechanical stretch every heart beat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::92e187c9f7b2d17fd909633f5a9b5b8b
https://doi.org/10.1161/res.115.suppl_1.284

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The long non-coding HOTAIR is modulated by cyclic stretch and WNT/β-CATENIN in human aortic valve cells and is a novel repressor of calcification genes

Autor: Jeffrey Dyo, Salah A. Mohamed, Gary Hardiman, Vishal Patel, Katrina Carrion, Vishal Nigam, Roman Sasik

Publikováno v: PLoS ONE, Vol 9, Iss 5, p e96577 (2014)
PLoS ONE

Aortic valve calcification is a significant and serious clinical problem for which there are no effective medical treatments. Individuals born with bicuspid aortic valves, 1–2% of the population, are at the highest risk of developing aortic valve c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d49d14379104a1581a65c6e3b968335
http://europepmc.org/articles/PMC4006892?pdf=render

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