Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Katrina Boeckeler"'
Autor:
Carine Rosse, Etienne Formstecher, Katrina Boeckeler, Yingming Zhao, Joachim Kremerskothen, Michael D White, Jacques H Camonis, Peter J Parker
Publikováno v:
PLoS Biology, Vol 7, Iss 11, p e1000235 (2009)
Atypical protein kinase C (aPKC) isoforms have been implicated in cell polarisation and migration through association with Cdc42 and Par6. In distinct migratory models, the Exocyst complex has been shown to be involved in secretory events and migrati
Externí odkaz:
https://doaj.org/article/95fc10a001594aa89e24f2036822ba77
Publikováno v:
Seminars in Cell & Developmental Biology
Understanding the mechanisms of drug action has been the primary focus for pharmacological researchers, traditionally using rodent models. However, non-sentient model systems are now increasingly being used as an alternative approach to better unders
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3e39ab50242f722806ec4004e1baca1
Autor:
Annette Müller-Taubenberger, David R. Soll, Hannah Alexander, Ralph R. Isberg, Ralph Gräf, Deborah Wessels, Zhiru Li, Stephen Alexander, Robin S.B. Williams, Katrina Boeckeler
Publikováno v:
Trends in Molecular Medicine. 12:415-424
The social amoeba Dictyostelium discoideum is increasingly being used as a simple model for the investigation of problems that are relevant to human health. This article focuses on several recent examples of Dictyostelium-based biomedical research, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c70fc5273a94ca244e009a90bdb59cf
https://doi.org/10.1016/j.molmed.2006.07.003
https://doi.org/10.1016/j.molmed.2006.07.003
Publikováno v:
European Journal of Cell Biology. 85:1047-1057
Activation of the mitogen-activated protein kinase (MAPK) cascade gives rise to a neuroprotective effect in a variety of cell types. The bipolar disorder treatment, valproic acid (VPA), increases the activity of this pathway by modulating extracellul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b1f02b9c4481c37c51ffb418ee67408
https://doi.org/10.1016/j.ejcb.2006.04.013
https://doi.org/10.1016/j.ejcb.2006.04.013
Autor:
David Frith, Peter J. Parker, Mark Linch, Michael Howell, Katrina Boeckeler, Majid Hafezparast, Carine Rossé, Karin Barnouin, Ali Sayed Morsi, Simone Radtke
Publikováno v:
Journal of cell science. 125(Pt 16)
In migrating NRK cells, aPKCs control the dynamics of turnover of paxillin-containing focal adhesions (FA) determining migration rate. Using a proteomic approach (two-dimensional fluorescence difference gel electrophoresis), dynein intermediate chain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3772f409169cd95fc50d52f5757f85b8
https://pubmed.ncbi.nlm.nih.gov/22553211
https://pubmed.ncbi.nlm.nih.gov/22553211
Publikováno v:
Journal of cell science. 123(Pt 16)
Members of the PKC superfamily have been implicated in various migratory models and in particular in spatially restricted processes. However, defining the precise local events that underlie the PKC-dependent processes is constrained by the unspecific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a51282f7bb6950bc9de1d9d7b0f69a2
https://pubmed.ncbi.nlm.nih.gov/20647370
https://pubmed.ncbi.nlm.nih.gov/20647370
Autor:
Carine Rossé, Stéphanie Kermorgant, Katrina Boeckeler, Mark Linch, Peter J. Parker, Angus J.M. Cameron
Publikováno v:
Nature reviews. Molecular cell biology. 11(2)
Networks of signal transducers determine the conversion of environmental cues into cellular actions. Among the main players in these networks are protein kinases, which can acutely and reversibly modify protein functions to influence cellular events.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07a63a7398097a12a7449252a06c2426
https://pubmed.ncbi.nlm.nih.gov/20094051
https://pubmed.ncbi.nlm.nih.gov/20094051
Autor:
Robin S.B. Williams, Katrina Boeckeler
Publikováno v:
eLS
The social amoeba, Dictyostelium discoideum, has been commonly used to investigate cell motility, signal transduction, cell type differentiation and development. With the recent completion of the genome and the increasing number of experimental tools
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c899f986e13a05ac3d8d5d188c02a902
https://doi.org/10.1002/9780470015902.a0006038
https://doi.org/10.1002/9780470015902.a0006038
Publikováno v:
BMC Developmental Biology
BMC Developmental Biology, Vol 6, Iss 1, p 12 (2006)
BMC Developmental Biology, Vol 6, Iss 1, p 12 (2006)
Background Calcineurin, the Ca2+/calmodulin-dependent protein phosphatase, plays important roles in various cellular processes in lower and higher eukaryotes. Here we analyze the role of calcineurin in the development of Dictyostelium discoideum by R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e47b06296a72aec07f4af5b8865c4671
https://pubmed.ncbi.nlm.nih.gov/16512895
https://pubmed.ncbi.nlm.nih.gov/16512895