Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Katrin Volkmann"'
Autor:
Mathieu Brochet, Mark O Collins, Terry K Smith, Eloise Thompson, Sarah Sebastian, Katrin Volkmann, Frank Schwach, Lia Chappell, Ana Rita Gomes, Matthew Berriman, Julian C Rayner, David A Baker, Jyoti Choudhary, Oliver Billker
Publikováno v:
PLoS Biology, Vol 12, Iss 3, p e1001806 (2014)
Many critical events in the Plasmodium life cycle rely on the controlled release of Ca²⁺ from intracellular stores to activate stage-specific Ca²⁺-dependent protein kinases. Using the motility of Plasmodium berghei ookinetes as a signalling par
Externí odkaz:
https://doaj.org/article/2e9ff0eabae14cb39898e2aeb02503e0
Publikováno v:
PLoS Pathogens, Vol 9, Iss 12, p e1003811 (2013)
Transmission of the malaria parasite to its vertebrate host involves an obligatory exoerythrocytic stage in which extensive asexual replication of the parasite takes place in infected hepatocytes. The resulting liver schizont undergoes segmentation t
Externí odkaz:
https://doaj.org/article/d6bf097e500c42f9867b762c3bacdeb4
Autor:
Katrin Volkmann, Claudia Pfander, Charlotte Burstroem, Malika Ahras, David Goulding, Julian C Rayner, Friedrich Frischknecht, Oliver Billker, Mathieu Brochet
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41409 (2012)
Alveolins, or inner membrane complex (IMC) proteins, are components of the subpellicular network that forms a structural part of the pellicle of malaria parasites. In Plasmodium berghei, deletions of three alveolins, IMC1a, b, and h, each resulted in
Externí odkaz:
https://doaj.org/article/92c4506048e24dc9a90e810cff6840f1
Autor:
Milica Vulin, Charly Jehanno, Atul Sethi, Ana Luísa Correia, Milan M. S. Obradović, Joana Pinto Couto, Marie-May Coissieux, Maren Diepenbruck, Bogdan-Tiberius Preca, Katrin Volkmann, Priska Auf der Maur, Alexander Schmidt, Simone Münst, Loïc Sauteur, Michal Kloc, Marta Palafox, Adrian Britschgi, Vincent Unterreiner, Olaf Galuba, Isabelle Claerr, Sandra Lopez-Romero, Giorgio G. Galli, Daniel Baeschlin, Ryoko Okamoto, Savas D. Soysal, Robert Mechera, Walter P. Weber, Thomas Radimerski, Mohamed Bentires-Alj
Publikováno v:
Oncogene. 41:4459-4473
Plasticity delineates cancer subtypes with more or less favourable outcomes. In breast cancer, the subtype triple-negative lacks expression of major differentiation markers, e.g., estrogen receptor α (ERα), and its high cellular plasticity results
Autor:
Jeremy L. Jenkins, Katrin Volkmann, Shelly Meeusen, Prisca Liberali, Karyn Colman, Ludivine Challet Meylan, Michael B. Stadler, Ilya Lukonin, Janine E. Baaten, Denise Serra, Rui Zhao, Francisca Maurer
Publikováno v:
Nature
The development of intestinal organoids from single adult intestinal stem cells in vitro recapitulates the regenerative capacity of the intestinal epithelium1,2. Here we unravel the mechanisms that orchestrate both organoid formation and the regenera
Autor:
Ryoko Okamoto, Luigi Terracciano, Mohamed Bentires-Alj, Marcel P. Trefny, Marcus Vetter, Alfred Zippelius, Joao C. Guimaraes, Walter P. Weber, Katrin Volkmann, Christian Kurzeder, Duvini De Silva, Ana Luísa Correia, Alexander Schmidt, Kirsten D. Mertz, Sandro Bruno, Priska Auf der Maur
The persistence of undetectable disseminated tumour cells (DTCs) after primary tumour resection poses a major challenge to effective cancer treatment1–3. These enduring dormant DTCs are seeds of future metastases, and the mechanisms that switch the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e5605845bcb14053a69e34fe5b09cd7
https://edoc.unibas.ch/90861/
https://edoc.unibas.ch/90861/
Autor:
Ana Luísa, Correia, Joao C, Guimaraes, Priska, Auf der Maur, Duvini, De Silva, Marcel P, Trefny, Ryoko, Okamoto, Sandro, Bruno, Alexander, Schmidt, Kirsten, Mertz, Katrin, Volkmann, Luigi, Terracciano, Alfred, Zippelius, Marcus, Vetter, Christian, Kurzeder, Walter Paul, Weber, Mohamed, Bentires-Alj
Publikováno v:
Nature. 594(7864)
The persistence of undetectable disseminated tumour cells (DTCs) after primary tumour resection poses a major challenge to effective cancer treatment
Autor:
Alexander Schmidt, Joao C. Guimaraes, Christian Kurzeder, Marcus Vetter, Mohamed Bentires-Alj, Alfred Zippelius, Duvini De Silva, Kirsten D. Mertz, Ana Luísa Correia, Walter P. Weber, Marcel P. Trefny, Sandro Bruno, Luigi Terracciano, Katrin Volkmann, Ryoko Okamoto, Priska Auf der Maur
Publikováno v:
Nature. 600:E7-E7
Autor:
EunBin Arin Kim, Elyse Kozlowski, Manuel Llinás, Katrin Volkmann, Sarah Sebastian, Oliver Billker, Mathieu Brochet, Paco Pino, Erin C. Bush, Dominique Soldati-Favre
Publikováno v:
Cell Host & Microbe
Cell Host & Microbe, Vol. 12, No 6 (2012) pp. 824-34
Cell Host & Microbe, Vol. 12, No 6 (2012) pp. 824-34
Summary A major obstacle in analyzing gene function in apicomplexan parasites is the absence of a practical regulatable expression system. Here, we identified functional transcriptional activation domains within Apicomplexan AP2 (ApiAP2) family trans
Autor:
Arnab Pain, Claudia Pfander, Michael A. Quail, Frank Schwach, William C. Skarnes, Katrin Volkmann, Julian C. Rayner, Barry Rosen, Mathieu Brochet, Thomas D. Otto, Oliver Billker, Burcu Anar
Publikováno v:
Nature Methods; Vol 8
Nature methods
Nature methods
In malaria parasites, the systematic experimental validation of drug and vaccine targets by reverse genetics is constrained by the inefficiency of homologous recombination and by the difficulty of manipulating adenine and thymine (A+T)-rich DNA of mo