Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Katrin Staniek"'
Autor:
Christopher Krewenka, Sandra Rizzi, Chi Huu Nguyen, Marcin Delijewski, Lars Gille, Katrin Staniek, Johanna Catharina Duvigneau, Khaled Radad, Andrea Müllebner, Barbara Kranner, Rudolf Moldzio
Publikováno v:
Antioxidants, Vol 12, Iss 4, p 858 (2023)
Thymoquinone (TQ), an active compound from Nigella sativa seeds, is often described as a pharmacologically relevant compound with antioxidative properties, while the synthesis of TQ in the plant via oxidations makes it inapplicable for scavenging rad
Externí odkaz:
https://doaj.org/article/c94a4ceb29904bbd87cba832233f9ed2
Autor:
Laura Machin, Martin Piontek, Sara Todhe, Katrin Staniek, Lianet Monzote, Werner Fudickar, Torsten Linker, Lars Gille
Publikováno v:
Molecules, Vol 27, Iss 20, p 6846 (2022)
Leishmaniasis is a vector-borne disease caused by protozoal Leishmania parasites. Previous studies have shown that endoperoxides (EP) can selectively kill Leishmania in host cells. Therefore, we studied in this work a set of new anthracene-derived EP
Externí odkaz:
https://doaj.org/article/90733c19152148ba8a2874239e0a959f
Autor:
Lianet Monzote, Yamilet Gutiérrez, Laura Machin, Katrin Staniek, Ramón Scull, Prabodh Satyal, Lars Gille, William N. Setzer
Publikováno v:
Scientia Pharmaceutica, Vol 88, Iss 3, p 31 (2020)
Current antileishmanial drugs are toxic, expensive, and resistance to them has emerged. Several studies have focused on natural products as alternatives. In the present work, the chemical composition, in vitro antileishmanial activity, cytotoxicity e
Externí odkaz:
https://doaj.org/article/ca7db1473f4d4571af8abf972eca8d43
Autor:
Gerald Geroldinger, Matthias Tonner, Werner Fudickar, Sritama De Sarkar, Aishwarya Dighal, Lianet Monzote, Katrin Staniek, Torsten Linker, Mitali Chatterjee, Lars Gille
Publikováno v:
Molecules, Vol 23, Iss 7, p 1680 (2018)
Leishmaniasis is a vector-borne disease caused by protozoal Leishmania. Because of resistance development against current drugs, new antileishmanial compounds are urgently needed. Endoperoxides (EPs) are successfully used in malaria therapy, and expe
Externí odkaz:
https://doaj.org/article/27020feb5bf34dbcbd4f6548cc7b6e7a
Publikováno v:
Antioxidants, Vol 5, Iss 1, p 2 (2016)
Linking peak energy metabolism to lifespan and aging remains a major question especially when focusing on lactation in females. We studied, if and how lactation affects in vitro mitochondrial oxygen consumption and mitochondrial fatty acid compositio
Externí odkaz:
https://doaj.org/article/ae93eb3d7f254c269ba4c38348365960
Autor:
Sritama De Sarkar, Avijit Sarkar, Aishwarya Dighal, Mitali Chatterjee, Lars Gille, Katrin Staniek, Deblina Sarkar
Publikováno v:
Parasitology Research. 118:335-345
Berberine chloride, a plant-derived isoquinoline alkaloid, has been demonstrated to have leishmanicidal activity, which is mediated by generation of a redox imbalance and depolarization of the mitochondrial membrane, resulting in a caspase-independen
Autor:
Deblina Sarkar, Katrin Staniek, Sasanka Chakrabarti, Sritama De Sarkar, Lars Gille, Mitali Chatterjee, Aishwarya Dighal, Avijit Sarkar
Publikováno v:
Parasitology. 146:511-520
Endoperoxides kill malaria parasitesviacleavage of their endoperoxide bridge by haem or iron, leading to generation of cytotoxic oxygen-centred radicals. In view of theLeishmaniaparasites having a relatively compromised anti-oxidant defense and high
Autor:
Thomas Rosenau, Markus Bacher, Lars Gille, Sritama De Sarkar, Gerald Geroldinger, Mitali Chatterjee, Katrin Staniek, Sophie Bergmann, Ramón Scull, Matthias Tonner, Lianet Monzote
Publikováno v:
Phytotherapy Research. 32:1729-1740
The antileishmanial activity of the essential oil (EO) from Chenopodium ambrosioides L. has been demonstrated in vitro and in animal models, attributed to the major components of the EO. This study focused on the effects of the three major EO compoun
Autor:
Halina Baran, Carina Kronsteiner, Melanie Bertignol-Spörr, Katrin Staniek, Berthold Kepplinger, Martin Attam
Publikováno v:
International Journal of Tryptophan Research, Vol 2016, Iss 9, Pp 17-29 (2016)
International Journal of Tryptophan Research : IJTR
International Journal of Tryptophan Research, Vol 9 (2016)
International Journal of Tryptophan Research : IJTR
International Journal of Tryptophan Research, Vol 9 (2016)
Previously, we demonstrated that the endogenous glutamate receptor antagonist kynurenic acid dose-dependently and significantly affected rat heart mitochondria. Now we have investigated the effects of L-tryptophan, L-kynurenine, 3-hydroxykynurenine a
Autor:
Sritama De Sarkar, Katrin Staniek, Laura Machín, Judith Quirgst, Lars Gille, Klaus Stolze, Lianet Monzote, Martin Walter, Gerald Geroldinger, Matthias Tonner, J. Catharina Duvigneau, Mitali Chatterjee
Publikováno v:
Biochem Pharmacol
Endoperoxides (EPs) appear to be promising drug candidates against protozoal diseases, including malaria and leishmaniasis. Previous studies have shown that these drugs need an intracellular activation to exert their pharmacological potential. The ef