Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Katrin Simmnacher"'
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2020)
Parkinson’s disease (PD) is the most frequently occurring movement disorder, with an increasing incidence due to an aging population. For many years, the post-mortem brain was regarded as the gold standard for the analysis of the human pathology of
Externí odkaz:
https://doaj.org/article/633ec386d4e04474bceaff1c6b569ad2
Autor:
Iryna Prots, Julian E. Alecu, Beate Winner, Razvan Marius Brazdis, Annika Dahms, Wei Xiang, Laurent Roybon, Sandra Lörentz, Daniel Marsch, Anna Brendler, Katrin Simmnacher, Yanni Schneider, Franz Marxreiter
Publikováno v:
Human Molecular Genetics
Parkinson’s disease (PD) is a neurodegenerative disorder characterized by protein inclusions mostly composed of aggregated forms of α-synuclein (α-Syn) and by the progressive degeneration of midbrain dopaminergic neurons (mDANs), resulting in mot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd8807a6a6de4f467f296ca3822dffd8
https://doi.org/10.1093/hmg/ddaa039
https://doi.org/10.1093/hmg/ddaa039
Autor:
Katrin Simmnacher, Florian Krach, Yanni Schneider, Lena Mautner, Iryna Prots, Laurent Roybon, Beate Winner, Wei Xiang, Paulina Klein, Julian E. Alecu
Publikováno v:
Experimental neurology. 334
Senescence was recently linked to neurodegeneration and astrocytes are one of the major cell types to turn senescent under neurodegenerative conditions. Senescent astrocytes were detected in Parkinson's disease (PD) patients' brains besides reactive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf1d0caa0e8a7fb9019201f627f2d980
https://pubmed.ncbi.nlm.nih.gov/32949572
https://pubmed.ncbi.nlm.nih.gov/32949572
Autor:
Wei Xiang, Christian Hannappel, Eliezer Masliah, Razvan-Marius Brazdis, Steven Havlicek, Katrin Simmnacher, André Reis, Iryna Prots, Mandy Krumbiegel, Vanesa Veber, Florian Krach, Beate Winner, Ursula Schlötzer-Schrehardt, Jürgen Winkler, Wolfgang Wrasidlo, Teja W. Groemer, Oliver Schütz, Janina Grosch, Douglas Galasko
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance α-Synuclein (α-Syn) aggregation underlies neurodegeneration in synucleinopathies. However, the nature of α-Syn aggregates and their toxic mechanisms in human pathology remains elusive. Here, we delineate a role of α-Syn oligomeric ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16af4e515c08777bbc70979ef1f4713b
https://doi.org/10.1073/pnas.1713129115
https://doi.org/10.1073/pnas.1713129115
Autor:
Daniel Thiel, Anke Jentsch, Juergen Kreyling, E. Willner, Carl Beierkuhnlein, Katrin Simmnacher
Publikováno v:
Ecography. 35:268-275
Late spring frost events can affect vegetation. The response of grassland species, however, is generally unknown. We explore the late-frost sensitivity of four common European grass species and investigate whether these species exhibit local adaptati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0dc305ecf3ddf12b752bafdb7f599470
https://doi.org/10.1111/j.1600-0587.2011.07173.x
https://doi.org/10.1111/j.1600-0587.2011.07173.x