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pro vyhledávání: '"Katrin Silbermann"'
Publikováno v:
Journal of General Virology. 89:2788-2798
The human T-cell leukemia virus type 1 (HTLV-1) Tax oncoprotein transforms human lymphocytes and is critical for the pathogenesis of HTLV-1-induced adult T-cell leukaemia. In HTLV-transformed cells, Tax upregulates interleukin (IL)-13, a cytokine wit
Autor:
Katrin Silbermann, Ralph Grassmann
Publikováno v:
Signal Transduction. 7:34-52
Human T cell leukemia virus type 1 (HTLV-1), a delta-retrovirus, causes an aggressive malignancy of T lymphocytes called adult T cell leukemia/lymphoma and stimulates permanent cell growth in culture. The virus encodes a nonstructural regulatory prot
Autor:
Katja Wäldele, Katrin Silbermann, Bryan R. Cullen, Grit Schneider, Ralph Grassmann, Tobias Ruckes
Publikováno v:
Blood. 107:4491-4499
Human T cell leukemia virus type 1 (HTLV-1), the cause of adult T cell leukemia (ATL), induces clonal expansion of infected T-cells in nonleukemic individuals and immortalizes T cells in vitro. The resistance against apoptotic stimuli of these cells