Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Katrin Scheibner"'
Autor:
Susanne Steinbrecht, Jan Kiebist, Rosalie König, Markus Thiessen, Kai-Uwe Schmidtke, Sarah Kammerer, Jan-Heiner Küpper, Katrin Scheibner
Publikováno v:
AMB Express, Vol 10, Iss 1, Pp 1-13 (2020)
Abstract Cyclophosphamide (CPA) represents a widely used anti-cancer prodrug that is converted by liver cytochrome P450 (CYP) enzymes into the primary metabolite 4-hydroxycyclophosphamide (4-OH-CPA), followed by non-enzymatic generation of the bioact
Externí odkaz:
https://doaj.org/article/02be8937c7c9421ca3f00981bdaa4085
Autor:
Rosalie König, Jan Kiebist, Johannes Kalmbach, Robert Herzog, Kai-Uwe Schmidtke, Harald Kellner, René Ullrich, Nico Jehmlich, Martin Hofrichter, Katrin Scheibner
Publikováno v:
Microorganisms, Vol 10, Iss 7, p 1267 (2022)
Lipid mediators, such as epoxidized or hydroxylated eicosanoids (EETs, HETEs) of arachidonic acid (AA), are important signaling molecules and play diverse roles at different physiological and pathophysiological levels. The EETs and HETEs formed by th
Externí odkaz:
https://doaj.org/article/7d38250e370f4af6b90a50dc921b327a
Autor:
Alejandro González-Benjumea, Gisela Marques, Owik M. Herold-Majumdar, Jan Kiebist, Katrin Scheibner, José C. del Río, Angel T. Martínez, Ana Gutiérrez
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2021)
Epoxides of vegetable oils and free and methylated fatty acids are of interest for several industrial applications. In the present work, refined rapeseed, sunflower, soybean, and linseed oils, with very different profiles of mono- and poly-unsaturate
Externí odkaz:
https://doaj.org/article/dd62e8fcb2c944f6b4e3ff14e6493065
Autor:
Esteban D. Babot, Carmen Aranda, Jan Kiebist, Katrin Scheibner, René Ullrich, Martin Hofrichter, Angel T. Martínez, Ana Gutiérrez
Publikováno v:
Antioxidants, Vol 11, Iss 3, p 522 (2022)
Terminal alkenes are among the most attractive starting materials for the synthesis of epoxides, which are essential and versatile intermediate building blocks for the pharmaceutical, flavoring, and polymer industries. Previous research on alkene epo
Externí odkaz:
https://doaj.org/article/125fb96832f8498ab47db80c438683cc
Autor:
Martin Hofrichter, Harald Kellner, Robert Herzog, Alexander Karich, Jan Kiebist, Katrin Scheibner, René Ullrich
Publikováno v:
Antioxidants, Vol 11, Iss 1, p 163 (2022)
Unspecific peroxygenases (UPOs), whose sequences can be found in the genomes of thousands of filamentous fungi, many yeasts and certain fungus-like protists, are fascinating biocatalysts that transfer peroxide-borne oxygen (from H2O2 or R-OOH) with h
Externí odkaz:
https://doaj.org/article/613e603401f84b2598bd1e4cb5917b2a
Cell-Free Protein Synthesis with Fungal Lysates for the Rapid Production of Unspecific Peroxygenases
Autor:
Marina Schramm, Stephanie Friedrich, Kai-Uwe Schmidtke, Jan Kiebist, Paul Panzer, Harald Kellner, René Ullrich, Martin Hofrichter, Katrin Scheibner
Publikováno v:
Antioxidants, Vol 11, Iss 2, p 284 (2022)
Unspecific peroxygenases (UPOs, EC 1.11.2.1) are fungal biocatalysts that have attracted considerable interest for application in chemical syntheses due to their ability to selectively incorporate peroxide-oxygen into non-activated hydrocarbons. Howe
Externí odkaz:
https://doaj.org/article/9b35775b943c46fba44b2b3d84b3612a
Autor:
Jan Kiebist, Kai-Uwe Schmidtke, Marina Schramm, Rosalie König, Stephan Quint, Johannes Kohlmann, Ralf Zuhse, René Ullrich, Martin Hofrichter, Katrin Scheibner
Publikováno v:
Journal of Fungi, Vol 7, Iss 9, p 752 (2021)
Antithrombotic thienopyridines, such as clopidogrel and prasugrel, are prodrugs that undergo a metabolic two-step bioactivation for their pharmacological efficacy. In the first step, a thiolactone is formed, which is then converted by cytochrome P450
Externí odkaz:
https://doaj.org/article/8d4c1b107522450a94ee6d7faa5716bd
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
Unspecific peroxygenases (UPOs) are secreted fungal enzymes with promiscuity for oxygen transfer and oxidation reactions. Functionally, they represent hybrids of P450 monooxygenases and heme peroxidases; phylogenetically they belong to the family of
Externí odkaz:
https://doaj.org/article/0304b4d8090b4ba5a06f5e9bb6f14e3c
Autor:
Patricia Gomez de Santos, Alejandro González‐Benjumea, Angela Fernandez‐Garcia, Carmen Aranda, Yinqi Wu, Andrada But, Patricia Molina‐Espeja, Diana M. Maté, David Gonzalez‐Perez, Wuyuan Zhang, Jan Kiebist, Katrin Scheibner, Martin Hofrichter, Katarzyna Świderek, Vicent Moliner, Julia Sanz‐Aparicio, Frank Hollmann, Ana Gutiérrez, Miguel Alcalde
Publikováno v:
Angewandte Chemie (International Edition), 62(9)
10 páginas.- 4 figuras.- 2 tablas.- 30 referencias.- Supporting information for this article is given via a link at the end of the document https://onlinelibrary.wiley.com/doi/10.1002/anie.202217372
he hydroxylation of fatty acids is an appeali
he hydroxylation of fatty acids is an appeali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a51083d6b87077f721f9a0b462c16c8
https://doi.org/10.1002/anie.202217372
https://doi.org/10.1002/anie.202217372
Autor:
Harald Kellner, Stephanie Friedrich, Kai-Uwe Schmidtke, René Ullrich, Jan Kiebist, Daniel Zänder, Martin Hofrichter, Katrin Scheibner
Publikováno v:
Microbiology resource announcements. 11(7)
The ascomycete Truncatella angustata has a worldwide distribution. Commonly, it is associated with plants as an endophyte, pathogen, or saprotroph. The genome assembly comprises 44.9 Mbp, a G+C content of 49.2%, and 12,353 predicted genes, among them
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0af0531478a164b1dc702bb7bb1b24c3
https://pubmed.ncbi.nlm.nih.gov/35658563
https://pubmed.ncbi.nlm.nih.gov/35658563