Zobrazeno 1 - 10
of 149
pro vyhledávání: '"Katrin Schäfer"'
Autor:
Rajinikanth Gogiraju, Claudius Witzler, Fatemeh Shahneh, Astrid Hubert, Luisa Renner, Magdalena L. Bochenek, Konstantinos Zifkos, Christian Becker, Madhusudhan Thati, Katrin Schäfer
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract Obesity promotes endothelial dysfunction. Endothelial cells not only respond, but possibly actively promote the development of obesity and metabolic dysfunction. Our aim was to characterize the role of endothelial leptin receptors (LepR) for
Externí odkaz:
https://doaj.org/article/1346dfb597974390a7527bafe2d5401b
Endothelial-dependent S-Sulfhydration of tissue factor pathway inhibitor regulates blood coagulation
Autor:
Janina Wittig, Maria-Kyriaki Drekolia, Anastasia Kyselova, Fredy Delgado Lagos, Magdalena L. Bochenek, Jiong Hu, Katrin Schäfer, Ingrid Fleming, Sofia-Iris Bibli
Publikováno v:
Redox Biology, Vol 62, Iss , Pp 102694- (2023)
Tissue factor pathway inhibitor (TFPI) is an important regulator of coagulation and a link between inflammation and thrombosis. Here we investigated whether endothelial cell-driven oxidative post-translational modifications could have an impact on TF
Externí odkaz:
https://doaj.org/article/c64a64aa8ebc45a1b6f1d0275628ebc7
Autor:
Janina Krug, Magdalena L. Bochenek, Rajinikanth Gogiraju, Dagmar Laubert-Reh, Karl J. Lackner, Thomas Münzel, Philipp S. Wild, Christine Espinola-Klein, Katrin Schäfer
Publikováno v:
Biomedicines, Vol 11, Iss 9, p 2459 (2023)
(1) Background: Endothelial dysfunction initiates cardiovascular pathologies, including peripheral artery disease (PAD). The pathophysiology of impaired new vessel formation in the presence of angiogenic stimuli, such as ischemia and inflammation, is
Externí odkaz:
https://doaj.org/article/66be3af2eedf4c68b01816ac1303bebe
Autor:
Magdalena L. Bochenek, Rajinikanth Gogiraju, Stefanie Großmann, Janina Krug, Jennifer Orth, Sabine Reyda, George S. Georgiadis, Henri M. Spronk, Stavros Konstantinides, Thomas Münzel, John H. Griffin, Philipp Wild, Christine Espinola-Klein, Wolfram Ruf, Katrin Schäfer
Publikováno v:
JCI Insight, Vol 7, Iss 14 (2022)
Blood clot formation initiates ischemic events, but coagulation roles during postischemic tissue repair are poorly understood. The endothelial protein C receptor (EPCR) regulates coagulation, as well as immune and vascular signaling, by protease acti
Externí odkaz:
https://doaj.org/article/0909dcd5f8c44e619cf8af8d0733a288
Autor:
Maria Pavlaki, Kateryna Moiko, Adina Thomaidis, George Chalikias, Katrin Schäfer, Stavros Konstantinides, Dimitrios Tziakas
Publikováno v:
TH Open, Vol 06, Iss 03, Pp e248-e250 (2022)
Externí odkaz:
https://doaj.org/article/56f9df9d49944bc992c7d13ecc33f0c0
Autor:
Katrin Schäfer
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 8, p 7527 (2023)
In recent decades, research has identified the key cellular processes that take place during atherosclerotic plaque development and progression, including endothelial dysfunction, inflammation and lipoprotein oxidation, which result in macrophage and
Externí odkaz:
https://doaj.org/article/0331a3fc1dbb43ec8da38febed40d03a
Autor:
Henning Formes, Joana P. Bernardes, Amrit Mann, Franziska Bayer, Giulia Pontarollo, Klytaimnistra Kiouptsi, Katrin Schäfer, Sebastian Attig, Teodora Nikolova, Thomas G. Hofmann, Jörn M. Schattenberg, Hristo Todorov, Susanne Gerber, Philip Rosenstiel, Tobias Bopp, Felix Sommer, Christoph Reinhardt
Publikováno v:
iScience, Vol 24, Iss 10, Pp 103092- (2021)
Summary: The gut microbiota affects remote organ functions but its impact on organotypic endothelial cell (EC) transcriptomes remains unexplored. The liver endothelium encounters microbiota-derived signals and metabolites via the portal circulation.
Externí odkaz:
https://doaj.org/article/ee0261277c8044a4afde1def618b2469
Autor:
Elsa Wilma Böhm, Maria Pavlaki, Georgios Chalikias, Dimitrios Mikroulis, George S. Georgiadis, Dimitrios N. Tziakas, Stavros Konstantinides, Katrin Schäfer
Publikováno v:
TH Open, Vol 05, Iss 02, Pp e113-e124 (2021)
Background Intimal calcification typically develops in advanced atherosclerosis, and microcalcification may promote plaque progression and instability. Conversely, intraplaque hemorrhage and erythrocyte extravasation may stimulate osteoblastic differ
Externí odkaz:
https://doaj.org/article/37306d5e6f184c32b369bc22c4a78637
Autor:
Sarah Zierold, Katja Buschmann, Sogol Gachkar, Magdalena L. Bochenek, David Velmeden, Lukas Hobohm, Christian‐Friedrich Vahl, Katrin Schäfer
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 6 (2021)
Background Brain‐derived neurotrophic factor (BDNF) is expressed in neuronal and nonneuronal cells and may affect vascular functions via its receptor, tropomyosin‐related kinase B (TrkB). In this study, we determined the expression of BDNF in dif
Externí odkaz:
https://doaj.org/article/84159d2c87ea40fe9a6376114fa1f822
Autor:
Magdalena L. Bochenek, Tobias Bauer, Rajinikanth Gogiraju, Yona Nadir, Amrit Mann, Tanja Schönfelder, Leonie Hünig, Benjamin Brenner, Thomas Münzel, Philip Wenzel, Stavros Konstantinides, Katrin Schäfer
Publikováno v:
Blood Advances, Vol 2, Iss 11, Pp 1300-1314 (2018)
Abstract: Venous thromboembolism (VTE) is a leading cause of morbidity and mortality in elderly people. Increased expression of tumor suppressor protein 53 (p53) has been implicated in vascular senescence. Here, we examined the importance of endothel
Externí odkaz:
https://doaj.org/article/528ff15599fe47138068cfaf86bdeea4