Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Katrin Sandau"'
Autor:
E. A. Higgs, G. Nisticò, Katrin Sandau, S. Moncada, Bernhard Brüne, G. Bagetta, Andreas von Knethen, Udo K. Messmer
Publikováno v:
Nitric Oxide and the Cell: Proliferation, Differentiation, and Death
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17b182d4df4078f4fd6c3af09a049d35
https://doi.org/10.1515/9781400887538-030
https://doi.org/10.1515/9781400887538-030
Autor:
Wen-Bin Ou, Katrin Sandau, Jonathan A. Fletcher, Peter J. Roberts, Margaret von Mehren, Heikki Joensuu, Christopher L. Corless, Karen McDougall, Michael Heinrich, Christopher D.M. Fletcher, Chang Jie Chen, Charles D. Blanke, George D. Demetri, Burton L. Eisenberg
Publikováno v:
Journal of Clinical Oncology. 24:4764-4774
PurposeGastrointestinal stromal tumors (GISTs) commonly harbor oncogenic mutations of the KIT or platelet-derived growth factor alpha (PDGFRA) kinases, which are targets for imatinib. In clinical studies, 75% to 90% of patients with advanced GISTs ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2730ee7ee7309021c7826ddfa71dc870
https://doi.org/10.1200/jco.2006.06.2265
https://doi.org/10.1200/jco.2006.06.2265
Publikováno v:
Cellular Signalling. 13:525-533
It is widely recognized that the production of nitric oxide (NO) from L-arginine metabolism is an essential determinate of diverse signalling cascades throughout the body, with a major impact during nonspecific host defence. Biological actions of NO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aab3d7b2ab6b61bc69f2c492b65b686
https://doi.org/10.1016/s0898-6568(01)00175-9
https://doi.org/10.1016/s0898-6568(01)00175-9
Publikováno v:
Blood. 97:1009-1015
The key player for adaptation to reduced oxygen availability is the transcription factor hypoxia-inducible factor 1 (HIF-1), composed of the redox-sensitive HIF-1α and the constitutively expressed HIF-1β subunits. Under normoxic conditions, HIF-1α
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86b5ec97a4474af122e4887730c9d5a8
https://doi.org/10.1182/blood.v97.4.1009
https://doi.org/10.1182/blood.v97.4.1009
Publikováno v:
Free Radical Biology and Medicine. 26:1544-1553
Platelet derived growth factor receptor (PDGFR) became tyrosine autophosphorylated in rat mesangial cells shortly after platelet derived growth factor (PDGF) ligation in a tyrosine kinase inhibitor (tyrphostin AG 1296) sensitive manner. Ligand-indepe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5049c0764a39155d469f607c84a0eda6
https://doi.org/10.1016/s0891-5849(99)00015-5
https://doi.org/10.1016/s0891-5849(99)00015-5
Publikováno v:
European Journal of Pharmacology. 342:77-84
The formation of nitric oxide (NO.) and superoxide (O2-) promotes rat mesangial cell death. Apoptotic death is characterized by DNA fragmentation, caspase-3 activation and concomitant poly(ADPribose) polymerase cleavage, as well as accumulation of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3487b18520bb729972bb6aa5ab47d9e
https://doi.org/10.1016/s0014-2999(97)01321-6
https://doi.org/10.1016/s0014-2999(97)01321-6
Publikováno v:
Kidney International. 52:378-386
Nitric oxide and superoxide induced p53 and Bax accumulation during mesangial cell apoptosis. During proliferative glomerulonephritis, the early phase of mesangiolysis is linked to increased nitric oxide (NO . ) production. NO . as well as superoxide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0884d7ccc8460d3b2da24ebf83dc248
https://doi.org/10.1038/ki.1997.344
https://doi.org/10.1038/ki.1997.344
Autor:
Udo K. Meßmer, Eduardo G. Lapetina, Christine Götz, Katrin Sandau, Bernhard Brüne, Maija-Riitta Hirvonen
Publikováno v:
Journal of Biological Chemistry. 272:7253-7258
RAW 264.7 macrophages, when challenged with a combination of lipopolysaccharide (10 microg/ml) and interferon-gamma (100 units/ml), respond with endogenous NO. formation, which ultimately results in apoptotic cell death. Apoptosis is detected morphol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1deea93215515675f361c7c2d4ba416d
https://doi.org/10.1074/jbc.272.11.7253
https://doi.org/10.1074/jbc.272.11.7253
Publikováno v:
European Journal of Pharmacology. 317:137-149
Renal mesangial cells exposed to inflammatory cytokines produce high concentrations of nitric oxide (NO) which may exert cytotoxic actions. We report here that glomerular mesangial cells, endothelial cells and epithelial cells in culture are themselv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b92ed01f54138424c6934831357cbd3c
https://doi.org/10.1016/s0014-2999(96)00701-7
https://doi.org/10.1016/s0014-2999(96)00701-7