Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Katrin Rupalla"'
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
BackgroundCancer remains one of the most common causes of morbidity and mortality worldwide. Multiregional (MRCTs) and single-country clinical trials are two common approaches to support new oncology drug approvals internationally. However, systemati
Externí odkaz:
https://doaj.org/article/f37dfb17e40a42dfa61e123ac2da808a
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
Jennifer Sheng, Matthew Tan, Gaurav Bajaj, Manish Gupta, Hwei‐Gene Heidi Wang, Richard Bertz, Jeffrey S. Barrett, Katrin Rupalla
Publikováno v:
Clinical Pharmacology & Therapeutics. 105:363-375
Cancer is a growing public health problem in China. Despite the high unmet medical need of patients with cancer in China, oncology drug approvals have historically lagged behind those in the West, mainly the United States and Europe. China is current
Publikováno v:
European Journal of Pharmacology. 294:469-473
We tested the effect of flupirtine against ischemic and excitotoxic neuronal damage as well as on the glutamate-induced rise in cytosolic calcium ion concentration (= [Ca2+]i). For in vivo experiments we used a model of focal cerebral ischemia in mic
Autor:
Hanan S. El-Abhar, Josef Krieglstein, Petra Henrich-Noack, Katrin Rupalla, Matthias Welsch, Franz Ausmeier, Klaus Lippert
Publikováno v:
European Journal of Pharmaceutical Sciences. 3:39-48
The neuroprotective effects of Ginkgo biloba extract (EGb 761) and some of its constituents were tested by using the mouse and the rat model of focal cerebral ischemia, the rat model of global cerebral ischemia and primary cultures of neurons obtaine
Autor:
Katrin Rupalla
Publikováno v:
Pharmaceuticals, Policy and Law. 12:71-72
The national scientific advice procedure can vary from country to country, with some national regulatory agencies not giving advice at all. Usually it is a face-toface meeting, for which there are no pre-specified dates. It can be requested at any ti
Autor:
Herman van der Putten, Ailsa L. McGregor, Serge Bischoff, Christoph Wiessner, Bernd W. Böttiger, Peter R. Allegrini, Tilman Oltersdorf, Dirk Sauer, Katrin Rupalla
Publikováno v:
Neuroscience letters. 268(3)
Protective effects after focal cerebral ischemia were assessed in transgenic mice that overexpress in a neuron-specific fashion mouse Bcl-X L or human Bcl-2 . Both Bcl genes were under the control of the same mouse Thy-1 regulatory sequences resultin