Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Katrin Reichel"'
Autor:
Tushar Jain, Bianka Prinz, Alexander Marker, Alexander Michel, Katrin Reichel, Valerie Czepczor, Sylvie Klieber, Wei Sun, Sagar Kathuria, Sevim Oezguer Bruederle, Christian Lange, Lena Wahl, Charles Starr, Alessandro Masiero, Lindsay Avery
Publikováno v:
mAbs, Vol 16, Iss 1 (2024)
In vitro assessments for the prediction of pharmacokinetic (PK) behavior of biotherapeutics can help identify corresponding liabilities significantly earlier in the discovery timeline. This can minimize the need for extensive early in vivo PK charact
Externí odkaz:
https://doaj.org/article/38817983990a4fd685f565a20d0c4cd1
Autor:
Yung-Ning Chang, Eva A. Jaumann, Katrin Reichel, Julia Hartmann, Dominik Oliver, Gerhard Hummer, Benesh Joseph, Eric R. Geertsma
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
The SLC26 family of transporters maintains anion equilibria in all kingdoms of life. Here, the authors resolve the structure of an SLC26 dimer embedded in a lipid membrane and characterize it by PELDOR/DEER distance measurements, biochemical studies
Externí odkaz:
https://doaj.org/article/f5ed26875ed64eea8d3ccd81bb3ef1c6
Autor:
Christoph Bock, Frank Löhr, Franz Tumulka, Katrin Reichel, Julia Würz, Gerhard Hummer, Lars Schäfer, Robert Tampé, Benesh Joseph, Frank Bernhard, Volker Dötsch, Rupert Abele
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Abstract The ATP-binding cassette transporter TAPL translocates polypeptides from the cytosol into the lysosomal lumen. TAPL can be divided into two functional units: coreTAPL, active in ATP-dependent peptide translocation, and the N-terminal membran
Externí odkaz:
https://doaj.org/article/848161c3458d4b778156d6e149516c9c
Publikováno v:
Research on Enterprise in Modern Economy Theory and Practice, Vol 3, Iss 3 (2012)
In recent years, the fact to make more use of the knowledge and expertise of people aged 55+ years – called “Best Agers” – has been increasingly recognized. The usage of these skills is becoming more and more important. Due to this finding, t
Externí odkaz:
https://doaj.org/article/89c1487877224610bc21c2e0ba70ea56
Autor:
Gerhard Hummer, Frank Bernhard, Robert Tampé, Rupert Abele, Lars V. Schäfer, Volker Dötsch, Julia M. Würz, Benesh Joseph, Franz Tumulka, Katrin Reichel, Frank Löhr, Christoph Bock
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific Reports
Scientific Reports
The ATP-binding cassette transporter TAPL translocates polypeptides from the cytosol into the lysosomal lumen. TAPL can be divided into two functional units: coreTAPL, active in ATP-dependent peptide translocation, and the N-terminal membrane spannin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f8c1f3419960c9e2d760ea8a033293f
https://doaj.org/article/848161c3458d4b778156d6e149516c9c
https://doaj.org/article/848161c3458d4b778156d6e149516c9c
Publikováno v:
The Journal of Physical Chemistry Letters. 9:5748-5752
Double electron-electron resonance (DEER) experiments probe nanometer-scale distances in spin-labeled proteins and nucleic acids. Rotamer libraries of the covalently attached spin-labels help reduce position uncertainties. Here we show that rotamer r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e78d7cd22b7a714b3ab4448f5cc4b88
https://doi.org/10.1021/acs.jpclett.8b02439
https://doi.org/10.1021/acs.jpclett.8b02439
Autor:
Olivier Fisette, Lars V. Schäfer, Katrin Reichel, Gerhard Hummer, Olivier F. Lange, Tatjana Braun
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 85:812-826
We critically test and validate the CS-Rosetta methodology for de novo structure prediction of α-helical membrane proteins (MPs) from NMR data, such as chemical shifts and NOE distance restraints. By systematically reducing the number and types of N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2974bdf25758f8392b3e00b50a06b6ac
https://doi.org/10.1002/prot.25224
https://doi.org/10.1002/prot.25224
Autor:
Eric R. Geertsma, Yung-Ning Chang, Eva A. Jaumann, Julia Hartmann, Katrin Reichel, Dominik Oliver, Benesh Joseph, Gerhard Hummer
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Nature Communications
Nature Communications
The SLC26 family of transporters maintains anion equilibria in all kingdoms of life. The family shares a 7 + 7 transmembrane segments inverted repeat architecture with the SLC4 and SLC23 families, but holds a regulatory STAS domain in addition. While
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60f04a464e8687ea4459178a10d148c7
Autor:
Katrin, Reichel, Olivier, Fisette, Tatjana, Braun, Oliver F, Lange, Gerhard, Hummer, Lars V, Schäfer
Publikováno v:
Proteins. 85(5)
We critically test and validate the CS-Rosetta methodology for de novo structure prediction of α-helical membrane proteins (MPs) from NMR data, such as chemical shifts and NOE distance restraints. By systematically reducing the number and types of N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e9250d2a35e44e1e3461bfc673e77cec
https://pubmed.ncbi.nlm.nih.gov/27936510
https://pubmed.ncbi.nlm.nih.gov/27936510
Autor:
Lars V. Schäfer, Katrin Reichel, Olivier Fisette, Rupert Abele, Gerhard Hummer, Andreas Blees, Simon Trowitzsch, Christoph Bock, Robert Tampé
Publikováno v:
Scientific Reports
Salt bridges in lipid bilayers play a decisive role in the dynamic assembly and downstream signaling of the natural killer and T-cell receptors. Here, we describe the identification of an inter-subunit salt bridge in the membrane within yet another k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e98e0978c6ad08c0b38f16afa185f39
https://doi.org/10.1038/srep17341
https://doi.org/10.1038/srep17341