Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Katrin Ramsauer"'
Autor:
Frédéric Vanhoutte, Wen Liu, Richard T. Wiedmann, Liesbeth Haspeslagh, Xin Cao, Keith Boundy, Antonios Aliprantis, Michelle Davila, Jonathan Hartzel, Jianing Li, Mac McGuire, Katrin Ramsauer, Yvonne Tomberger, Roland Tschismarov, Deborah D. Brown, Weifeng Xu, Jeffrey R. Sachs, Kevin Russell, S. Aubrey Stoch, Eseng Lai
Publikováno v:
EBioMedicine, Vol 75, Iss , Pp 103811- (2022)
Summary: Background: We report on the safety and immunogenicity of V591, a measles vector-based SARS-CoV-2 vaccine candidate. Methods: In this multicentre, randomised, placebo-controlled, double-blind, phase 1/2 trial, healthy adults with no history
Externí odkaz:
https://doaj.org/article/d59aa9653c964fe6ac6e01ea17db7d32
Autor:
Odile Launay, Cécile Artaud, Marie Lachâtre, Mohand Ait-Ahmed, Jelle Klein, Liem Binh Luong Nguyen, Christine Durier, Bastiaan Jansen, Yvonne Tomberger, Nathalie Jolly, Anna Grossmann, Houda Tabbal, Jérémy Brunet, Marion Gransagne, Zaineb Choucha, Damien Batalie, Ana Delgado, Matthias Müllner, Roland Tschismarov, Pieter-Jan Berghmans, Annette Martin, Katrin Ramsauer, Nicolas Escriou, Christiane Gerke
Publikováno v:
EBioMedicine, Vol 75, Iss , Pp 103810- (2022)
Summary: Background: V591 (TMV-083) is a live recombinant measles vector-based vaccine candidate expressing a pre-fusion stabilized SARS-CoV-2 spike protein. Methods: We performed a randomized, placebo-controlled Phase I trial with an unblinded dose
Externí odkaz:
https://doaj.org/article/f5f7bf1bca4a49cba23dddea87bed0ca
Autor:
Roland Tschismarov, Raphaël M. Zellweger, Min Jie Koh, Yan Shan Leong, Jenny G. Low, Eng Eong Ooi, Christian W. Mandl, Katrin Ramsauer, Ruklanthi de Alwis
Publikováno v:
JCI Insight, Vol 6, Iss 21 (2021)
Chikungunya is a mosquito-borne disease that causes periodic but explosive epidemics of acute disease throughout the tropical world. Vaccine development against chikungunya virus (CHIKV) has been hampered by an inability to conduct efficacy trials du
Externí odkaz:
https://doaj.org/article/af56162da81644c2bd6b091d01c0e266
Publikováno v:
Expert Review of Vaccines, Vol 18, Iss 4, Pp 393-403 (2019)
Introduction: The large global burden of viral infections and especially the rapidly spreading vector-borne diseases and other emerging viral diseases show the need for new approaches in vaccine development. Several new vaccine technology platforms h
Externí odkaz:
https://doaj.org/article/cc4166df1c8141a1b08a0b28e227ceb4
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Arboviruses represent major challenges to public health, particularly in tropical, and subtropical regions, and a substantial risk to other parts of the world as respective vectors extend their habitats. In recent years, two viruses transmitted by Ae
Externí odkaz:
https://doaj.org/article/6643e6279d1a4dbb9e3635dd7e0de3b4
Autor:
Sabrina Schrauf, Yvonne Tomberger, Sham Nambulli, W. Paul Duprex, Roland Tschismarov, Erich Tauber, Katrin Ramsauer
Publikováno v:
Journal of applied toxicology : JATREFERENCES.
MV-LASV is an investigational measles Schwarz-based vaccine for the prevention of Lassa fever. A repeated-dose toxicity study in cynomolgus macaques was performed to assess the biodistribution and local and systemic toxicological effects. Monkeys rec
Autor:
Shannan L. Rossi, William S Lawrence, Sabrina Schrauf, Jessica A. Plante, Eryu Wang, Jason E. Comer, Scott C. Weaver, Katrin Ramsauer, Sasha R. Azar
Publikováno v:
The Journal of Infectious Diseases
Background Chikungunya virus (CHIKV) infection can result in chikungunya fever (CHIKF), a self-limited acute febrile illness that can progress to chronic arthralgic sequelae in a large percentage of patients. A new measles virus-vectored vaccine was
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology, Vol 11 (2020)
Arboviruses represent major challenges to public health, particularly in tropical, and subtropical regions, and a substantial risk to other parts of the world as respective vectors extend their habitats. In recent years, two viruses transmitted by Ae
Autor:
Farid Sari-Sarraf, Gillis R. Otten, Timothy Pepini, Thomas Carsillo, Carlo Iavarone, Jeffrey B. Ulmer, Dong Yu, Alicia L. Carlson, Giulietta Maruggi, Jason C. Debasitis, Katrin Ramsauer, Anne-Marie Pulichino, Andrew Geall
Publikováno v:
The Journal of Immunology. 198:4012-4024
RNA-based vaccines have recently emerged as a promising alternative to the use of DNA-based and viral vector vaccines, in part because of the potential to simplify how vaccines are made and facilitate a rapid response to newly emerging infections. SA
Autor:
Katrin Ramsauer, Frédéric Tangy
Publikováno v:
Journal of Infectious Diseases. 214:S500-S505
In 2013, a major chikungunya virus (CHIKV) epidemic reached the Americas. In the past 2 years, >1.7 million people have been infected. In light of the current epidemic, with millions of people in North and South America at risk, efforts to rapidly de