Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Katrin Rabold"'
Autor:
Katrin Rabold, Martijn Zoodsma, Inge Grondman, Yunus Kuijpers, Manita Bremmers, Martin Jaeger, Bowen Zhang, Willemijn Hobo, Han J. Bonenkamp, Johannes H. W. de Wilt, Marcel J. R. Janssen, Lenneke A. M. Cornelissen, Ilse C. H. van Engen-van Grunsven, Willem J. M. Mulder, Jan W. A. Smit, Gosse J. Adema, Mihai G. Netea, Yang Li, Cheng-Jian Xu, Romana T. Netea-Maier
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Myeloid cells contribute to the tumor microenvironment of thyroid cancers, but their functional relevance is lesser known. Here authors show that myeloid cells infiltrating non-medullary thyroid carcinomas upregulate their antigen presentation-relate
Externí odkaz:
https://doaj.org/article/8df2ed731e6144a6a49c050153ca4af0
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 412 (2023)
Lenvatinib is a multitarget tyrosine kinase inhibitor (TKI) approved for the treatment of several types of cancers, including metastatic differentiated thyroid cancer (DTC). The intended targets include VEGFR 1–3, FGFR 1–4, PDGFRα, RET, and KIT
Externí odkaz:
https://doaj.org/article/2f4219a385784d44b068ca463d95891e
Autor:
Kalijn F. Bol, Gerty Schreibelt, Katrin Rabold, Stefanie K. Wculek, Julia Katharina Schwarze, Andrzej Dzionek, Alvaro Teijeira, Lana E. Kandalaft, Pedro Romero, George Coukos, Bart Neyns, David Sancho, Ignacio Melero, I. Jolanda M. de Vries
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-13 (2019)
Abstract Dendritic cells (DCs) can initiate and direct adaptive immune responses. This ability is exploitable in DC vaccination strategies, in which DCs are educated ex vivo to present tumor antigens and are administered into the patient with the aim
Externí odkaz:
https://doaj.org/article/60c7d9af6efc49e6b0a2c0c42c52a283
Autor:
Jorge Domínguez-Andrés, Rob J.W. Arts, Siroon Bekkering, Harsh Bahrar, Bastiaan A. Blok, L. Charlotte J. de Bree, Mariolina Bruno, Özlem Bulut, Priya A. Debisarun, Helga Dijkstra, Jéssica Cristina dos Santos, Anaísa V. Ferreira, Daniela Flores-Gomez, Laszlo A. Groh, Inge Grondman, Leonie Helder, Cor Jacobs, Liesbeth Jacobs, Trees Jansen, Gizem Kilic, Viola Klück, Valerie A.C.M. Koeken, Heidi Lemmers, Simone J.C.F.M. Moorlag, Vera P. Mourits, Jelmer H. van Puffelen, Katrin Rabold, Rutger J. Röring, Diletta Rosati, Helin Tercan, Julia van Tuijl, Jessica Quintin, Reinout van Crevel, Niels P. Riksen, Leo A.B. Joosten, Mihai G. Netea
Publikováno v:
STAR Protocols, Vol 2, Iss 1, Pp 100365- (2021)
Summary: A growing number of studies show that innate immune cells can undergo functional reprogramming, facilitating a faster and enhanced response to heterologous secondary stimuli. This concept has been termed “trained immunity.” We outline he
Externí odkaz:
https://doaj.org/article/e0ee4ea53a9e4be785098507068f1cd9
Autor:
Mihai G Netea, Katrin Rabold, Gosse J Adema, Anna Aschenbrenner, Christoph Thiele, Collins K Boahen, Alexander Schiltmans, Johannes W A Smit, Joachim L Schultze, Romana T Netea-Maier
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Tumor-associated macrophages (TAMs) are key components of the tumor microenvironment (TME) in non-medullary thyroid carcinoma (TC) and neuroblastoma (NB), being associated with a poor prognosis for patients. However, little is known about
Externí odkaz:
https://doaj.org/article/3294f8726d5844c5ad59e3f4c36af538
Autor:
Thomas Crezee, Hans Morreau, Marika H Tesselaar, Adriana C. H. van Engen-van Grunsven, Willem E. Corver, Martin Jaeger, Jan W. A. Smit, Katrin Rabold, Romana T. Netea‑Maier, Theo S. Plantinga
Publikováno v:
Oncology Letters, 22, 2
Oncology Letters, 22
Oncology Letters
Oncology Letters, 22(2). SPANDIDOS PUBL LTD
Oncology Letters, 22
Oncology Letters
Oncology Letters, 22(2). SPANDIDOS PUBL LTD
Differentiated thyroid cancer (DTC) is the most frequent endocrine tumor with a good prognosis after primary treatment in most cases. By contrast, 30-40% of patients with metastatic DTC are unresponsive to I-131 radioactive iodide (RAI) treatment due
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1514e500b68161574f7910cf946583d2
https://hdl.handle.net/1887/3276818
https://hdl.handle.net/1887/3276818
Autor:
Katrin Rabold, Liesbeth Jacobs, Jéssica Cristina dos Santos, Leo A. B. Joosten, Heidi Lemmers, Laszlo Groh, Viola Klück, Harsh Bahrar, Inge Grondman, Trees Jansen, Gizem Kilic, Priya A. Debisarun, Reinout van Crevel, Vera P. Mourits, Rutger J. Röring, Leonie Helder, Jelmer H. van Puffelen, Diletta Rosati, Jorge Domínguez-Andrés, Niels P. Riksen, Anaisa V. Ferreira, Bastiaan A. Blok, L. Charlotte J. de Bree, Mihai G. Netea, Valerie A. C. M. Koeken, Cor Jacobs, Rob J.W. Arts, Helga Dijkstra, Daniela Flores-Gomez, Julia van Tuijl, Jessica Quintin, Simone J.C.F.M. Moorlag, Helin Tercan, Mariolina Bruno, Ozlem Bulut, Siroon Bekkering
Publikováno v:
STAR Protocols
STAR Protocols, 2
STAR Protocols, Vol 2, Iss 1, Pp 100365-(2021)
STAR Protocols, 2, 1
STAR Protocols, 2
STAR Protocols, Vol 2, Iss 1, Pp 100365-(2021)
STAR Protocols, 2, 1
Summary A growing number of studies show that innate immune cells can undergo functional reprogramming, facilitating a faster and enhanced response to heterologous secondary stimuli. This concept has been termed “trained immunity.” We outline her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7b20cf0ee143c59f9170a1a6f3ff814
https://doi.org/10.1016/j.xpro.2021.100365
https://doi.org/10.1016/j.xpro.2021.100365
Publikováno v:
Cancers, 13, 22
Cancers, Vol 13, Iss 5695, p 5695 (2021)
Cancers
Cancers, 13
Cancers, Vol 13, Iss 5695, p 5695 (2021)
Cancers
Cancers, 13
Simple Summary In this review, we evaluate the updated data of the immunological effects of kinase inhibitors on the innate immune system and provide an in-depth analysis of the underlying mechanisms. We also discuss how this immunological effect can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9a73e50cf06ad46acf15bf983d649af
Autor:
Jan W. A. Smit, Hans Morreau, Willem E. Corver, Martin Jaeger, R.T. Netea-Maier, Thomas Crezee, Katrin Rabold, Theo S. Plantinga, Marika H Tesselaar, Adriana C. H. van Engen-van Grunsven
Background: Non-medullary thyroid cancer (NMTC) is the most frequent endocrine tumor with in most cases a good prognosis after thyroidectomy and 131I radioactive iodide (RAI) ablation. In contrast, 30-40% of patients with metastatic NMTC are unrespon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25485806b03e0f894f1f4d748c98ad86
https://doi.org/10.21203/rs.3.rs-89212/v1
https://doi.org/10.21203/rs.3.rs-89212/v1
Autor:
Gosse J. Adema, Collins K. Boahen, Mihai G. Netea, Katrin Rabold, Romana T. Netea-Maier, Anna C. Aschenbrenner, Alexander Schiltmans, Christoph Thiele, Joachim L. Schultze, Johannes W. A. Smit
Publikováno v:
Journal for Immunotherapy of Cancer, 8
Journal for Immunotherapy of Cancer, 8, 2
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer, 8, 2
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Journal for Immunotherapy of Cancer
BackgroundTumor-associated macrophages (TAMs) are key components of the tumor microenvironment (TME) in non-medullary thyroid carcinoma (TC) and neuroblastoma (NB), being associated with a poor prognosis for patients. However, little is known about h