Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Katrin Orlowski"'
Autor:
Markus Hecht, Dennis Hahn, Philipp Wolber, Matthias G. Hautmann, Dietmar Reichert, Steffi Weniger, Claus Belka, Tobias Bergmann, Thomas Göhler, Manfred Welslau, Christina Große-Thie, Orlando Guntinas-Lichius, Jens von der Grün, Panagiotis Balermpas, Katrin Orlowski, Diethelm Messinger, Karsten G. Stenzel, Rainer Fietkau
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-11 (2020)
Abstract Background Head and neck squamous cell cancer (HNSCC) frequently causes severe symptoms that may be reduced, when the tumor is successfully treated. The SOCCER trial studied the association of treatment response with patient reported tumor s
Externí odkaz:
https://doaj.org/article/b0e785e23cee4e3ebc4a8def0086024d
Autor:
Katrin Orlowski, Carla Rohrer Bley, Martina Zimmermann, Van Vuong, Daniel Hug, Alex Soltermann, Angela Broggini-Tenzer, Martin Pruschy
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51476 (2012)
Tumor hypoxia is one of the most important parameters that determines treatment sensitivity and is mainly due to insufficient tumor angiogenesis. However, the local oxygen concentration in a tumor can also be shifted in response to different treatmen
Externí odkaz:
https://doaj.org/article/8a06410a02304c7aa2f1065746b8b900
Autor:
Katrin Orlowski, Dietmar Reichert, Panagiotis Balermpas, Matthias G. Hautmann, T. Bergmann, Rainer Fietkau, D Hahn, Manfred Welslau, Claus Belka, Karsten G. Stenzel, Jens von der Grün, Steffi Weniger, Markus Hecht, Thomas Göhler, Christina Große-Thie, Orlando Guntinas-Lichius, Diethelm Messinger, Philipp Wolber
Publikováno v:
Cancers
Volume 13
Issue 14
Cancers, Vol 13, Iss 3413, p 3413 (2021)
Volume 13
Issue 14
Cancers, Vol 13, Iss 3413, p 3413 (2021)
Treatment options of locoregional recurrent head and neck squamous cell cancer (HNSCC) include both local strategies as surgery or re-radiotherapy and systemic therapy. In this prospective, multi-center, non-interventional study, patients were treate
Autor:
Carla Rohrer Bley, Martin Pruschy, Paul M.J. McSheehy, Katrin Orlowski, Polina Furmanova, Wolfram Jochum, Van Vuong
Publikováno v:
Clinical Cancer Research. 15:1335-1342
Purpose: The combined treatment modality of ionizing radiation (IR) and the clinically relevant microtubule-stabilizing compound patupilone (epothilone B, EPO906) is a promising approach for anticancer therapy. Here, we investigated the role of the t
Autor:
Daniel Hug, Angela Broggini-Tenzer, Van Vuong, Sabine Bender, Katrin Orlowski, Ashish Sharma, Martin Pruschy, Katarzyna J. Nytko, Terence O’Reilly
Publikováno v:
Journal of National Cancer Institute
Background: Resistance to microtubule-stabilizing agents is a major hurdle for successful cancer therapy. We investigated combined treatment of microtubule-stabilizing agents (MSAs) with inhibitors of angiogenesis to overcome MSA resistance. Methods:
Autor:
Martin Pruschy, Rolf A. Stahel, Thomas M. Marti, Emanuela Felley-Bosco, Katrin Orlowski, Yandong Shi
Publikováno v:
BMC Cancer, Vol 12, Iss 1, p 571 (2012)
BMC Cancer
BMC Cancer
Background Optimizing the safety and efficacy of standard chemotherapeutic agents such as cisplatin (CDDP) is of clinical relevance. Serum starvation in vitro and short-term food starvation in vivo both stress cells by the sudden depletion of paracri
Autor:
G. Illerhaus, Thomas Göhler, M. Aßmann, Markus Hecht, Rainer Fietkau, M. Finzsch, R. Wurm, Katrin Orlowski, Dietmar Reichert, L. Renziehausen, Manfred Welslau, Panagiotis Balermpas, Claus Belka, D. Hahn, D. Beutner, T. Bergmann
Publikováno v:
Annals of Oncology. 27:vi343
Autor:
Martin Pruschy, Polina Furmanova, Carla Rohrer Bley, Paul M.J. McSheehy, Angela Broggini-Tenzer, Katrin Orlowski, Nicole Grosse
Publikováno v:
European journal of cancer (Oxford, England : 1990). 49(1)
Combined radiochemotherapy treatment modalities are in use for many indications and therefore of high interest. Even though a combined modality in clinical use is often driven by pragmatic aspects, mechanistic preclinical-based concepts of interactio
Autor:
Karl Frei, Christoph Oehler, Polina Furmanova, Martin Pruschy, Stefan Rutkowski, Michael A. Grotzer, André O. von Bueren, Katrin Orlowski, Angela Broggini-Tenzer
Concurrent radiochemotherapy for medulloblastoma includes the microtubule disrupting agent vincristine; however, vincristine alone or as part of a combined treatment regimen is highly toxic. A major goal is therefore to replace vincristine with novel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a7eee7298082e4567973ecbfcd79ef8
https://doi.org/10.5167/uzh-49706
https://doi.org/10.5167/uzh-49706
Publikováno v:
Lung cancer (Amsterdam, Netherlands). 73(3)
The use of microtubule stabilizing agents (MSAs) is a promising strategy for anti-cancer therapy alone and as part of combined treatment modalities with ionizing radiation. However MSA-provoked molecular and cellular processes including the regulatio