Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Katrin Manda"'
Autor:
Bernd Frerker, Felix Bock, Marie-Louise Cappel, Stephan Kriesen, Gunther Klautke, Guido Hildebrandt, Katrin Manda
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 12, p 10385 (2023)
To date, oxaliplatin and irinotecan are used in combination with 5-flourouracil (5-FU) for metastatic colorectal cancer. In this study it was tested whether oxaliplatin and irinotecan and their combinations with 5-FU have an enhanced effect when trea
Externí odkaz:
https://doaj.org/article/e0bb9f5458dc4b7abb3dd1c67fe91cec
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 15, p 8548 (2022)
In our study, our aim was to examine the cytotoxic and radio-sensitizing effect of the alkaloid piperine, a major pungent of black pepper, on two different human epithelial tumor cell lines in vitro. The growth of the human cell lines T98G (glioblast
Externí odkaz:
https://doaj.org/article/cecba56733a74905aa424a65520ebe76
Autor:
Annegret Glasow, Ina Patties, Nicholas D. Priest, Ronald E. J. Mitchel, Guido Hildebrandt, Katrin Manda
Publikováno v:
Cells, Vol 10, Iss 11, p 3251 (2021)
Anti-inflammatory low-dose therapy is well established, whereas the immunomodulatory impact of doses below 0.1 Gy is much less clear. In this study, we investigated dose, dose rate and time-dependent effects in a dose range of 0.005 to 2 Gy on immune
Externí odkaz:
https://doaj.org/article/1da165c7c1974c26970ed2de992897c2
Autor:
Dajana Juerß, Monique Zwar, Ulrich Giesen, Ralf Nolte, Stephan Kriesen, Giorgio Baiocco, Monika Puchalska, Marc-Jan van Goethem, Katrin Manda, Guido Hildebrandt
Publikováno v:
Radiation Oncology, Vol 12, Iss 1, Pp 1-10 (2017)
Abstract Background As there is a growing number of long-term cancer survivors, the incidence of carcinogenesis as a late effect of radiotherapy is getting more and more into the focus. The risk for the development of secondary malignant neoplasms mi
Externí odkaz:
https://doaj.org/article/472d29f5f20548b2b72b4a91bf169954
Autor:
Sabine Schröder, Simone Broese, Jana Baake, Dajana Juerß, Stephan Kriesen, Guido Hildebrandt, Katrin Manda
Publikováno v:
Journal of Immunology Research, Vol 2019 (2019)
Purpose. Most tumours are characterized by an inflammatory microenvironment, and correlations between inflammation and cancer progression have been shown. Endothelial cells (ECs), as part of the tumour microenvironment, play a crucial role in inflamm
Externí odkaz:
https://doaj.org/article/1320f4af48164c45a662c394a8a6567d
Publikováno v:
Journal of Immunology Research, Vol 2018 (2018)
Background. In many European countries, patients with a variety of chronical inflammatory diseases are treated with low-dose radiotherapy (LD-RT). In contrast to high-dose irradiation given to tumor patients, little is known about radiobiological mec
Externí odkaz:
https://doaj.org/article/e319db85c6aa4a6882ced64817ed7458
Autor:
Paul Fischer, Annelie Koenen, Dajana Juerß, Guido Hildebrandt, Katrin Manda, Annemarie Schröder
Publikováno v:
Investigational New Drugs
Summary Background Statins inhibit the cholesterol biosynthesis and are used as cholesterol-lowering agents in fat-metabolism disorders. Furthermore, several studies state that statins have supportive functions in breast cancer treatment. Therefore,
Radiosensitizing effects of trabectedin on human A549 lung cancer cells and HT-29 colon cancer cells
Publikováno v:
Investigational New Drugs. 38:967-976
Background and Purpose Trabectedin is a unique alkylating agent with promising effects against a range of solid tumors. In this study, we aimed to examine the cytotoxic and radiosensitizing effects of trabectedin on two human epithelial tumor cell li
Publikováno v:
Medical Oncology (Northwood, London, England)
Sodium selenite is often given to moderate the side effects of cancer therapy to enhance the cellular defence of non-cancerous cells. To determine whether sodium selenite during radiotherapy protects not only normal cells but also cancer cells, which
Publikováno v:
Cytotechnology. 70:701-711
Partial breast irradiation of early breast cancer patients after lumpectomy and the use of endogenous adipose tissue (AT) for breast reconstruction are promising applications to reduce the side effects of breast cancer therapy. This study tries to in