Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Katrin Lorenz-Baath"'
Autor:
Stephan Morys, Josefine Roemmler-Zehrer, Katrin Lorenz-Baath, Bernhard Korge, Uwe Schwichtenberg, Stefanie Fritzlar, Kristian Reich, Natalie Nunez Gomez
Publikováno v:
Journal of the American Academy of Dermatology. 83:AB124
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15c36fe52e9eef712e4431703e13bfa8
https://doi.org/10.1016/j.jaad.2020.06.586
https://doi.org/10.1016/j.jaad.2020.06.586
Autor:
Kristian Reich, Natalie Nunez Gomez, Bernhard Korge, Katrin Lorenz-Baath, Stephan Morys, Stefanie Fritzlar, Josefine Roemmler-Zehrer, Uwe Schwichtenberg
Publikováno v:
Journal of the American Academy of Dermatology. 83:AB124
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d4d8dc042c8aec6f9312ac2996b4640
https://doi.org/10.1016/j.jaad.2020.06.585
https://doi.org/10.1016/j.jaad.2020.06.585
Autor:
Martin H. Kunzmann, Stephan A. Sieber, Thomas Böttcher, Joanna Krysiak, Oliver Baron, Franziska Weinandy, Jan Vomacka, Katrin Lorenz-Baath, Vadim S. Korotkov, Bianca Bauer
Publikováno v:
Chemistry - A European Journal. 22:1622-1630
Methicillin-resistant Staphylococcus aureus (MRSA) causes severe infections with only few effective antibiotic therapies currently available. To approach this challenge, chemical entities with a novel and resistance-free mode of action are desperatel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4288a364dbbb1f6a125edea8b174ba35
https://doi.org/10.1002/chem.201503981
https://doi.org/10.1002/chem.201503981
Autor:
Klaus Richter, Marie-Theres Vielberg, Markus Lakemeyer, Vadim S. Korotkov, Martin L. Stein, Herbert Waldmann, Axel Pahl, Jan Vomacka, Christian Fetzer, Mathias W. Hackl, Michael Groll, Katrin Lorenz-Baath, Stephan A. Sieber
Publikováno v:
Angewandte Chemie. 127:16121-16126
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28a85ee467da08ba2e87f5b0223c2cf7
https://doi.org/10.1002/ange.201507266
https://doi.org/10.1002/ange.201507266
Autor:
Herbert Waldmann, Iris Antes, Maria Dahmen, Sonja Sievers, Thomas Böttcher, Manuel Glaser, Axel Pahl, Mathias W. Hackl, Stephan A. Sieber, Katrin Lorenz-Baath, Markus Lakemeyer, Thomas Menzel
Publikováno v:
Journal of the American Chemical Society. 137:8475-8483
Caseinolytic protease P (ClpP) represents a central bacterial degradation machinery that is involved in cell homeostasis and pathogenicity. The functional role of ClpP has been studied by genetic knockouts and through the use of beta-lactones, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a75f6d94b7034d63efcd26cdb6f2461e
https://doi.org/10.1021/jacs.5b03084
https://doi.org/10.1021/jacs.5b03084
Autor:
Katrin Lorenz-Baath, Franziska Weinandy, Stephan A. Sieber, Vadim S. Korotkov, Shneh Sethi, Trinad Chakraborty, Thomas Böttcher
Publikováno v:
ChemMedChem. 9:710-713
Skin infections caused by Staphylococcus aureus are a major clinical concern, especially if they are caused by multi-resistant strains. In these cases, a spread into deeper soft tissues or the bloodstream results in life-threatening conditions that a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54ce1e88c76675d9f228267027b637a6
https://doi.org/10.1002/cmdc.201300325
https://doi.org/10.1002/cmdc.201300325
Publikováno v:
ChemMedChem. 7:1490-1495
Bacterial infections of skin and soft tissue represent a major health threat, especially if they are caused by multidrug-resistant strains such as MRSA. Novel treatment options for topical application are urgently needed, and even if new drug candida
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91f5cdeb083a941362c387aa83a44a17
https://doi.org/10.1002/cmdc.201200229
https://doi.org/10.1002/cmdc.201200229
Autor:
Martin L. Stein, Christian Fetzer, Michael Groll, Jan Vomacka, Stephan A. Sieber, Klaus Richter, Herbert Waldmann, Mathias W. Hackl, Katrin Lorenz-Baath, Axel Pahl, Markus Lakemeyer, Vadim S. Korotkov, Marie-Theres Vielberg
Publikováno v:
Angewandte Chemie (International ed. in English). 54(52)
Caseinolytic protease P (ClpP) is an important regulator of Staphylococcus aureus pathogenesis. A high-throughput screening for inhibitors of ClpP peptidase activity led to the identification of the first non-covalent binder for this enzyme class. Co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34fc72fbe4625c9e1e7ac4f4f0abe729
https://pubmed.ncbi.nlm.nih.gov/26566002
https://pubmed.ncbi.nlm.nih.gov/26566002
Autor:
Reinhard Fässler, Esra Karakose, Tamar Geiger, Roy Zent, Matthias Mann, Kevin C. Flynn, Katrin Lorenz-Baath
Publikováno v:
Journal of Cell Science.
PINCH-1 is a LIM-only domain protein that forms a ternary complex with integrin-linked kinase (ILK) and parvin (to form the IPP complex) downstream of integrins. Here, we demonstrate that PINCH-1 (also known as Lims1) gene ablation in the epidermis o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03bcba50141e1695d7ad97af079335db
https://doi.org/10.1242/jcs.162545
https://doi.org/10.1242/jcs.162545
Publikováno v:
Bioorganicmedicinal chemistry. 20(2)
Here, we report the synthesis and in depth characterization of a second generation β-lactone derived virulence inhibitors. Based on initial results that emphasized the intriguing possibility to disarm bacteria in their virulence the present study de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58cc80731b8f0464ad1d9e65391bffb9
https://pubmed.ncbi.nlm.nih.gov/21855356
https://pubmed.ncbi.nlm.nih.gov/21855356