Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Katrin Kierdorf"'
Autor:
Dennis-Dominik Rosmus, Jana Koch, Annika Hausmann, Aude Chiot, Franz Arnhold, Takahiro Masuda, Katrin Kierdorf, Stefanie Marie Hansen, Heidrun Kuhrt, Janine Fröba, Julian Wolf, Stefaniya Boneva, Martin Gericke, Bahareh Ajami, Marco Prinz, Clemens Lange, Peter Wieghofer
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-20 (2024)
Abstract Background The eye is a highly specialized sensory organ which encompasses the retina as a part of the central nervous system, but also non-neural compartments such as the transparent vitreous body ensuring stability of the eye globe and a c
Externí odkaz:
https://doaj.org/article/e84c464330be4cb09d23fcdd4acbbb4d
Publikováno v:
STAR Protocols, Vol 5, Iss 3, Pp 103145- (2024)
Summary: Tissue-resident macrophages (TRMs) constitute the first line of defense against infection in all organs and perform organ-specific functions during tissue homeostasis. Here, we present a protocol for long-term monocultures of murine macropha
Externí odkaz:
https://doaj.org/article/726d1222b1924e1a86c88ade70bb4070
Autor:
Fabian Hersperger, Tim Meyring, Pia Weber, Chintan Chhatbar, Gianni Monaco, Marc S Dionne, Katrin Paeschke, Marco Prinz, Olaf Groß, Anne-Kathrin Classen, Katrin Kierdorf
Publikováno v:
eLife, Vol 12 (2024)
Environmental factors, infection, or injury can cause oxidative stress in diverse tissues and loss of tissue homeostasis. Effective stress response cascades, conserved from invertebrates to mammals, ensure reestablishment of homeostasis and tissue re
Externí odkaz:
https://doaj.org/article/73eb2793298442e9a0c9ec15b7293262
Autor:
Peipei Zhang, Anja Schlecht, Julian Wolf, Stefaniya Boneva, Yannik Laich, Jana Koch, Franziska Ludwig, Myriam Boeck, Adrian Thien, Carmen Härdtner, Katrin Kierdorf, Hansjürgen Agostini, Günther Schlunck, Marco Prinz, Ingo Hilgendorf, Peter Wieghofer, Clemens Lange
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-18 (2021)
Abstract Background Microglia cells represent the resident innate immune cells of the retina and are important for retinal development and tissue homeostasis. However, dysfunctional microglia can have a negative impact on the structural and functiona
Externí odkaz:
https://doaj.org/article/f0b2242fbf2d4c6787d1cd668f61b8e7
Autor:
Crystal M Vincent, Esteban J Beckwith, Carolina J Simoes da Silva, William H Pearson, Katrin Kierdorf, Giorgio F Gilestro, Marc S Dionne
Publikováno v:
PLoS Pathogens, Vol 18, Iss 9, p e1010826 (2022)
Host behavioural changes are among the most apparent effects of infection. 'Sickness behaviour' can involve a variety of symptoms, including anorexia, depression, and changed activity levels. Here, using a real-time tracking and behavioural profiling
Externí odkaz:
https://doaj.org/article/4d39238a1b314f91bfe654c56671cdb7
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Microglia build the first line of defense in the central nervous system (CNS) and play central roles during development and homeostasis. Indeed, they serve a plethora of diverse functions in the CNS of which many are not yet fully described and more
Externí odkaz:
https://doaj.org/article/a88c259d122647d2862bfeeb4948821f
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Microglia, the innate immune cells of the CNS parenchyma, serve as the first line of defense in a myriad of neurodevelopmental, neurodegenerative, and neuroinflammatory conditions. In response to the peripheral inflammation, circulating mediators, an
Externí odkaz:
https://doaj.org/article/4bdaa29b9ff64537b6d35b38381c1f10
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Externí odkaz:
https://doaj.org/article/01b152bb97e34b0ba62beb3618b802fc
Publikováno v:
eLife, Vol 10 (2021)
At the transition from intrauterine to postnatal life, drastic alterations are mirrored by changes in cellular immunity. These changes are in part immune cell intrinsic, originate in the replacement of fetal cells, or result from global regulatory me
Externí odkaz:
https://doaj.org/article/659eaf60aa534c999cbccbdb061db1fc
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The central nervous system (CNS) harbors its own immune system composed of microglia in the parenchyma and CNS-associated macrophages (CAMs) in the perivascular space, leptomeninges, dura mater, and choroid plexus. Recent advances in understanding th
Externí odkaz:
https://doaj.org/article/58d39510109b43c19ce7d1002041cff4