Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Katrin I. Tiffner"'
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Topically applied drug products have experienced an extraordinary price increase in the United States, mostly due to a lack of generic products. Generic drug development is hindered by high costs and risks associated with clinical endpoint studies re
Externí odkaz:
https://doaj.org/article/98c2ac868a6f470eb6456f5aa1cbc1d5
Autor:
Judith C.J. Holzer, Petra Kotzbeck, Thomas Lemarchand, M Funk, Helmut Laaff, Sonja Kainz, Lars-Peter Kamolz, Ives Bernardelli de Mattos, Thomas Birngruber, Ayse Bal, Peter Reisenegger, Katrin I. Tiffner
Publikováno v:
Burns. 46:1924-1932
Background Burn wound progression is a significant problem as burns initially thought to be superficial can actually become full thickness over time. Cooling is an efficient method to reduce burn wound conversion. However, if the cooling agent is bel
Autor:
Beate Boulgaropoulos, Simon Schwingenschuh, Katrin I. Tiffner, Elena Rantou, Sam G. Raney, Manfred Bodenlenz, Thomas Birngruber, Frank Sinner, Thomas Augustin
Publikováno v:
Pharmaceutical Research
Purpose Dermal open flow microperfusion (dOFM) has previously demonstrated its utility to assess the bioequivalence (BE) of topical drug products in a clinical study. We aimed to characterize the sources of variability in the dermal pharmacokinetic d
Autor:
Sam G. Raney, Thomas Augustin, Isadore Kanfer, Reingard Raml, Katrin I. Tiffner, Frank Sinner
Publikováno v:
International Journal of Pharmaceutics. 609:121186
The aim was to evaluate whether an in vitro release test (IVRT) could differentiate the release rates from five pharmaceutically equivalent acyclovir cream products and one ointment compared to that from a reference product, Zovirax cream (USA), to i
Autor:
Petra Kotzbeck, Katrin I. Tiffner, J.C. Holzer-Geißler, M Funk, Elisabeth Hofmann, Lars-Peter Kamolz, Anita Eberl, Thomas Birngruber
Publikováno v:
Journal of Investigative Dermatology. 141:S212
Autor:
Ørjan G. Martinsen, Thomas Augustin, Reingard Raml, Katrin I. Tiffner, Christian Hoefferer, Frank Sinner, Simon Schwingenschuh, E.-C. Prandl, Beate Boulgaropoulos, Christian Dragatin, Hermann Scharfetter, Martin Hajnsek
Publikováno v:
Physiological Measurement. 38:N138-N150
Objective: Pharmacokinetic and pharmacodynamic studies of topically applied drugs are commonly performed by sampling of interstitial fluid with dermal open flow microperfusion and subsequent analysis of the samples. However, the reliability of result
Autor:
Selma Mautner, Sebastian P. Nischwitz, Lars-Peter Kamolz, Thomas Birngruber, Hanna Luze, M Funk, Judith C.J. Holzer, Sonja Kainz, Peter Reisenegger, Katrin I. Tiffner
Publikováno v:
Journal of Burn Care & Research. 41:S152-S153
Introduction Cooling of burn injuries is most important, not only to reduce pain but also to reduce the intradermal damage as well as the burn wound conversion. Studies have shown that cooling for about 20 to 30 minutes using only plain tap water at
Autor:
Reingard Raml, Thomas Augustin, Sam G. Raney, Katrin I. Tiffner, Frank Sinner, Isadore Kanfer
Publikováno v:
International journal of pharmaceutics. 535(1-2)
The rate of release of an active pharmaceutical ingredient (API) from a topical semisolid dosage form can be influenced by its physical and structural properties. An In Vitro Release Test (IVRT) is an established method to characterize this rate of A
Autor:
Selma Mautner, Peter Reisenegger, M Funk, Katrin I. Tiffner, Alexandru-Cristian Tuca, Thomas Birngruber, Judith C.J. Holzer, Sonja Kainz, Lars-Peter Kamolz
Publikováno v:
Journal of Burn Care & Research. 40:S149-S149
Autor:
Julia K. Mader, Frank Sinner, Gerard Bruin, Katrin I. Tiffner, Yi Cheng, Florine Polus, Christian Loesche, Christian Dragatin, Claudio Calonder, Manfred Bodenlenz, Birgit Aigner, Thomas R. Pieber, Ralph Woessner, Maria Ratzer
Publikováno v:
Experimental Dermatology. 25:157-159