Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Katrin Hücking"'
Autor:
Darko Stefanovski, Vahe Mooradian, Karyn J. Catalano, Jenny D. Chiu, Stella P. Kim, Justin Dittmann, Dan Zheng, Orison O. Woolcott, Morvarid Kabir, Cathryn M. Kolka, Richard N. Bergman, Gregg W. Van Citters, Sophia Yae, Maya Lottati, Marilyn Ader, Viorica Ionut, Lisa N. Harrison, Huiwen Liu, Katrin Hücking, Joyce M. Richey, Isabel R. Hsu, Martin Ellmerer, Ana Valeria B. Castro
Publikováno v:
Obesity. 22:1238-1245
Objective Insulin resistance is a powerful risk factor for Type 2 diabetes and a constellation of chronic diseases, and is most commonly associated with obesity. We examined if factors other than obesity are more substantial predictors of insulin sen
Publikováno v:
Obesity. 16:1938-1945
Insulin resistance is an important risk factor for diabetes and other diseases. It has been important to estimate insulin resistance in epidemiological and genetic studies involving significant number of individuals. Complex and invasive protocols ar
Publikováno v:
Obesity. 15:2416-2423
Objective: Recent studies have shown that free fatty acid (FFA) release is pulsatile and that this pattern is controlled by the sympathetic nervous system. It is, then, necessary to understand and characterize adipose tissue lipolysis to elucidate it
Autor:
Idit F. Liberty, Dan Zheng, Katrin Hücking, Maya Lottati, Darko Stefanovski, Viorica Ionut, Richard N. Bergman
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 291:E779-E785
The insulinotropic intestinal hormone GLP-1 is thought to exert one of its effects by direct action on the pancreatic beta-cell receptors. GLP-1 is rapidly degraded in plasma, such that only a small amount of the active form reaches the pancreas, mak
Autor:
Martin Ellmerer, Katrin Hücking, Richard N. Bergman, Marianthe Hamilton-Wessler, Stella P. Kim, Erlinda L. Kirkman
Publikováno v:
Diabetes. 53:2741-2747
Pharmacological doses of insulin increase limb blood flow and enhance tissue recruitment for small solutes such as glucose. We investigated whether elevating insulin within the physiological range (68 ± 6 vs. 425 ± 27 pmol/l) can influence tissue r
Publikováno v:
Journal of Clinical Investigation. 111:257-264
Rapid oscillations of visceral lipolysis have been reported. To examine the putative role of the CNS in oscillatory lipolysis, we tested the effects of beta(3)-blockade on pulsatile release of FFAs. Arterial blood samples were drawn at 1-minute inter
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 85:3575-3581
Gastric inhibitory polypeptide (GIP) is susceptible to degradation, but only recently has dipeptidyl peptidase IV been identified as the enzyme responsible. Most RIAs recognize both intact GIP-(1–42) and the noninsulinotropic N-terminally truncated
Autor:
Jenny D. Chiu, Richard N. Bergman, Karyn J. Catalano, Stella P. Kim, Katrin Hücking, Isabel R. Hsu, Marilyn Ader, Morvarid Kabir
Publikováno v:
Obesity (Silver Spring, Md.). 14
A consensus has emerged that fat stored in the central segment of the body is particularly damaging in that it portends greater risk for diabetes, cardiovascular disease, hypertension, and certain cancers (1–3). It is also accepted that insulin res
Autor:
Richard N. Bergman, Stella P. Kim, Joyce M. Richey, Viorica Ionut, Marilyn Ader, Katrin Hücking, Karyn J. Catalano, Morvarid Kabir
Publikováno v:
Diabetes. 54(3)
Atypical antipsychotics have been linked to weight gain, hyperglycemia, and diabetes. We examined the effects of atypical antipsychotics olanzapine (OLZ) and risperidone (RIS) versus placebo on adiposity, insulin sensitivity (S(I)), and pancreatic be
Autor:
Andrea El-Ouaghlidi, Katrin Hücking, Jens J. Holst, Wolfgang E. Schmidt, Michael A. Nauck, Juris J. Meier, Carolyn F. Deacon, Baptist Gallwitz, Bartholomäus Gabrys
Publikováno v:
Regulatory peptides. 122(3)
Aims/Hypothesis: Since insulin secretion in response to exogenous gastric inhibitory polypeptide (GIP) is diminished not only in patients with type 2 diabetes, but also in their normal glucose-tolerant first-degree relatives, it was the aim to invest