Heat Treatment of Poloxamer-Stabilized Triglyceride Nanodispersions: Effects and Underlying Mechanism

Autor: Heike Bunjes, Elin Roese, Katrin Göke

Publikováno v: Molecular Pharmaceutics. 15:3111-3120

Lipid nanoemulsions are being investigated for the parenteral administration of poorly soluble drugs. A narrow particle size distribution in these formulations is a prerequisite for meaningful research and safe administration to patients. Autoclaving

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8809f2d513583f129e62190291c0e3fd
https://doi.org/10.1021/acs.molpharmaceut.8b00202

Control over Particle Size Distribution by Autoclaving Poloxamer-Stabilized Trimyristin Nanodispersions

Autor: Heike Bunjes, Elin Roese, Judith Kuntsche, Andreas Arnold, Katrin Göke

Publikováno v: Göke, K, Roese, E, Arnold, A, Kuntsche, J & Bunjes, H 2016, ' Control over particle size distribution by autoclaving poloxamer-stabilized trimyristin nanodispersions ', Molecular Pharmaceutics, vol. 13, no. 9, pp. 3187-3195 . https://doi.org/10.1021/acs.molpharmaceut.6b00395

Lipid nanoparticles are under investigation as delivery systems for poorly water-soluble drugs. The particle size in these dispersions strongly influences important pharmaceutical properties like biodistribution and drug loading capacity; it should b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b7db6e0d8e47efdebad79f640e28bd3
https://doi.org/10.1021/acs.molpharmaceut.6b00395

Drug solubility in lipid nanocarriers: Influence of lipid matrix and available interfacial area

Autor: Heike Bunjes, Katrin Göke

Publikováno v: International journal of pharmaceutics. 529(1-2)

Amongst other strategies for the formulation of poorly water-soluble drugs, solubilization of these drugs in lipid-based formulations is a promising option. Most screening methods for the identification of a suitable lipid-based formulation fail to e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::494fec89db27638b4fb34382e3ca825c
https://pubmed.ncbi.nlm.nih.gov/28705617

Alkynyl gold(I) phosphane complexes: evaluation of structure-activity-relationships for the phosphane ligands, effects on key signaling proteins and preliminary in-vivo studies with a nanoformulated complex

Autor: Malte Kokoschka, Ingo Ott, Chi-Ming Che, Raymond Wai-Yin Sun, Heike Bunjes, Laura Rodríguez, Elisabet Aguiló, Katrin Göke, Stefan Wölfl, Vincent Andermark, Luciano Oehninger, Mohamed A. Abu el Maaty, Taotao Zou, Ching Tung Lum

Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona

Gold alkynyl complexes with phosphane ligands of the type (alkynyl)Au(I)(phosphane) represent a group of bioorganometallics, which has only recently been evaluated biologically in more detail. Structure-activity-relationship studies regarding the res

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6b0e0e51348481ddf02be39a500d40c
http://hdl.handle.net/2445/152519