Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Katrin Demski"'
Autor:
Oliver Plettenburg, Isabel Hamp, Thomas J. O’Neill, Carina Graß, Daniel Krappmann, Torben Gehring, Marie J. Tofaute, Andreas Gewies, Ronald Naumann, Katrin Demski, Henrik Schmidt, Martin Göttlicher, Florian Giesert, Marc Rosenbaum, Katharina Kriegsmann, Wolfgang Wurst, Thomas Seeholzer, Mark Kriegsmann, Theresa Schnalzger, Jürgen Ruland, Vigo Heissmeyer, Tanja Poth
Publikováno v:
Science immunology 6(65), eabh2095 (2021). doi:10.1126/sciimmunol.abh2095
Balanced control of T cell signaling is critical for adaptive immunity and protection from autoimmunity. By combining genetically engineered mouse models, biochemical analyses and pharmacological interventions, we describe an unexpected dual role of
Autor:
Daniel Nagel, Hana Velvarska, Ute Greczmiel, Dierk Niessing, Daniel Krappmann, Katrin Demski, Ana C. Messias, Ralf Stehle, Michelle Vincendeau, Kamyar Hadian, Jenny Halander, Michael Sattler, Jara Kerstin Brenke, Arie Geerlof, Richard A. Griesbach, Arianna Bertossi
Publikováno v:
Sci. Rep. 6:18934 (2016)
Scientific Reports
Scientific Reports
The IκB kinase (IKK) complex acts as the gatekeeper of canonical NF-κB signaling, thereby regulating immunity, inflammation and cancer. It consists of the catalytic subunits IKKα and IKKβ and the regulatory subunit NEMO/IKKγ. Here, we show that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b9ac1b3e98796538788a3698027a255
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=47656
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=47656
Autor:
Kamyar Hadian, Sebastian C. Warth, Vigo Heissmeyer, Gisela Schimmack, Katrin Demski, Michael Düwel, Hisaaki Shinohara, Daniel Krappmann, Wolfgang Beisker, Andrea C. Eitelhuber, Tomohiro Kurosaki
Publikováno v:
The EMBO Journal. 30:594-605
The Carma1–Bcl10–Malt1 (CBM) complex bridges T-cell receptor (TCR) signalling to the canonical IκB kinase (IKK)/NF-κB pathway. NF-κB activation is triggered by PKCθ-dependent phosphorylation of Carma1 after TCR/CD28 co-stimulation. PKCθ-phos
Autor:
Tomohiro Kurosaki, Hisaaki Shinohara, Andrea C. Eitelhuber, Katrin Demski, Michelle Vincendeau, Daniel Krappmann, Gisela Schimmack
Publikováno v:
Cell Communication and Signaling : CCS
Cell Commun. Signal. 12:49 (2014)
Cell Commun. Signal. 12:49 (2014)
Background: The CARMA1-BCL10-MALT1 (CBM) complex bridges T cell receptor (TCR) signaling to the canonical I kappa B kinase (IKK)/NF-kappa B pathway. The CBM complex constitutes a signaling cluster of more than 1 Mio Dalton. Little is known about fact