Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Katrin Bundkirchen"'
Publikováno v:
Cell Transplantation, Vol 33 (2024)
Bone marrow–derived mesenchymal stromal cells (BMSCs) are attractive candidates in tissue engineering and regenerative medicine. Growing evidence has suggested that a high body mass index (BMI) can affect the properties of BMSCs, resulting in a red
Externí odkaz:
https://doaj.org/article/62043e1f561a44edacf2a56e0332dd9b
Autor:
Yuzhuo Zhou, Fanshuai Meng, Kernt Köhler, Jasmin Maria Bülow, Alessa Wagner, Claudia Neunaber, Katrin Bundkirchen, Borna Relja
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
BackgroundTrauma, a significant global cause of mortality and disability, often leads to fractures and hemorrhagic shock, initiating an exaggerated inflammatory response, which harms distant organs, particularly the lungs. Elderly individuals are mor
Externí odkaz:
https://doaj.org/article/13a787c392e24f76af37d04dc12a35a9
Autor:
Fanshuai Meng, Yuzhuo Zhou, Alessa Wagner, Jasmin Maria Bülow, Kernt Köhler, Claudia Neunaber, Katrin Bundkirchen, Borna Relja
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundTrauma causes disability and mortality globally, leading to fractures and hemorrhagic shock. This can trigger an irregular inflammatory response that damages remote organs, including liver. Aging increases the susceptibility to dysregulated
Externí odkaz:
https://doaj.org/article/3354fabeed7046539604098ac60f48e2
Autor:
Laurens Noack, Katrin Bundkirchen, Baolin Xu, Severin Gylstorff, Yuzhuo Zhou, Kernt Köhler, Phatcharida Jantaree, Claudia Neunaber, Aleksander J. Nowak, Borna Relja
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundTrauma is the third leading cause of mortality worldwide. Upon admission, up to 50% of traumatized patients are acutely intoxicated with alcohol, which might lead to aberrant immune responses. An excessive and uncontrolled inflammatory resp
Externí odkaz:
https://doaj.org/article/37133246db4243b8b414a33ec1a80387
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 5, p 4831 (2023)
Bone marrow-derived mesenchymal stem cells (BMSCs) are promising candidates for cell-based therapies. Growing evidence has indicated that overweight/obesity can change the bone marrow microenvironment, which affects some properties of BMSCs. As the o
Externí odkaz:
https://doaj.org/article/82a6b1361fff40c4ba27474a5986f24d
Autor:
Elisa Katja Westerkowsky, Adriana Marisa Soares de Almeida, Michael Selle, Oliver Harms, Katrin Bundkirchen, Claudia Neunaber, Sandra Noack
Publikováno v:
Life, Vol 13, Iss 3, p 718 (2023)
For research and clinical use of stem cells, a suitable animal model is necessary. Hence, the aim of this study was to compare human-bone-marrow-derived mesenchymal stem cells (hBMSCs) with those from sheep (oBMSCs) and pigs (pBMSCs). The cells from
Externí odkaz:
https://doaj.org/article/25c195a9e6034598bb1416b39bde5f86
Autor:
Katrin Bundkirchen, Weikang Ye, Aleksander J. Nowak, Stefan Lienenklaus, Bastian Welke, Borna Relja, Claudia Neunaber
Publikováno v:
Bioengineering, Vol 10, Iss 1, p 70 (2023)
Femoral fractures and severe bleeding frequently occur in old patients showing a delayed healing. As there are no studies investigating the combined effect of high age and severe blood loss on fracture healing, this was examined radiographically and
Externí odkaz:
https://doaj.org/article/fd506991242a4d8f941ef6f8d24d824d
Autor:
Yazhou Long, Katrin Bundkirchen, Pascal Gräff, Christian Krettek, Sandra Noack, Claudia Neunaber
Publikováno v:
Stem Cells International, Vol 2021 (2021)
Due to their immunomodulatory and regenerative capacity, human bone marrow-derived mesenchymal stem cells (hBMSCs) are promising in the treatment of patients suffering from polytrauma. However, few studies look at the effects of sera from polytraumat
Externí odkaz:
https://doaj.org/article/65ff7d1135c34ae1afa12c19d769a3c3
Autor:
Valentin Schrodi, Claudia Neunaber, Katrin Bundkirchen, Weikang Ye, Zhida Jiang, Maximilian Petri, Christian Krettek, Sandra Noack
Publikováno v:
Stem Cells International, Vol 2021 (2021)
Mesenchymal stem cells play an important role in regenerative medicine due to their capability of self-renewal and multipotent differentiation. For research or clinical application, bone marrow aspirates are harvested during elective surgeries to iso
Externí odkaz:
https://doaj.org/article/c6769d62f15c4a3cb692b7d48247b39d
Autor:
Jil-Madeline Homeier, Katrin Bundkirchen, Marcel Winkelmann, Tilman Graulich, Borna Relja, Claudia Neunaber, Christian Macke
Publikováno v:
Life, Vol 11, Iss 11, p 1252 (2021)
While improvements in pre-hospital and in-hospital care allow more multiple trauma patients to advance to intensive care, the incidence of posttraumatic multiple organ dysfunction syndrome (MODS) is on the rise. Herein, the influence of a selective I
Externí odkaz:
https://doaj.org/article/a58d6cc9e9ee402693e996a4d191012b