Polygenic risk scores across the extended psychosis spectrum

Autor: Lukasz Smigielski, Sergi Papiol, Anastasia Theodoridou, Karsten Heekeren, Miriam Gerstenberg, Diana Wotruba, Roman Buechler, Per Hoffmann, Stefan Herms, Kristina Adorjan, Heike Anderson-Schmidt, Monika Budde, Ashley L. Comes, Katrin Gade, Maria Heilbronner, Urs Heilbronner, Janos L. Kalman, Farahnaz Klöhn-Saghatolislam, Daniela Reich-Erkelenz, Sabrina K. Schaupp, Eva C. Schulte, Fanny Senner, Ion-George Anghelescu, Volker Arolt, Bernhard T. Baune, Udo Dannlowski, Detlef E. Dietrich, Andreas J. Fallgatter, Christian Figge, Markus Jäger, Georg Juckel, Carsten Konrad, Vanessa Nieratschker, Jens Reimer, Eva Reininghaus, Max Schmauß, Carsten Spitzer, Martin von Hagen, Jens Wiltfang, Jörg Zimmermann, Anna Gryaznova, Laura Flatau-Nagel, Markus Reitt, Milena Meyers, Barbara Emons, Ida Sybille Haußleiter, Fabian U. Lang, Thomas Becker, Moritz E. Wigand, Stephanie H. Witt, Franziska Degenhardt, Andreas J. Forstner, Marcella Rietschel, Markus M. Nöthen, Till F. M. Andlauer, Wulf Rössler, Susanne Walitza, Peter Falkai, Thomas G. Schulze, Edna Grünblatt

Publikováno v: Translational Psychiatry, Vol 11, Iss 1, Pp 1-11 (2021)

Abstract As early detection of symptoms in the subclinical to clinical psychosis spectrum may improve health outcomes, knowing the probabilistic susceptibility of developing a disorder could guide mitigation measures and clinical intervention. In thi

Externí odkaz: https://doaj.org/article/057a8222a0e64555a64d03d86616addf

Stability over time of scores on psychiatric rating scales, questionnaires and cognitive tests in healthy controls

Autor: Katharina Stahl, Kristina Adorjan, Heike Anderson-Schmidt, Monika Budde, Ashley L. Comes, Katrin Gade, Maria Heilbronner, Janos L. Kalman, Farahnaz Klöhn-Saghatolislam, Mojtaba Oraki Kohshour, Sergi Papiol, Daniela Reich-Erkelenz, Sabrina K. Schaupp, Eva C. Schulte, Fanny Senner, Thomas Vogl, Jens Wiltfang, Eva Reininghaus, Peter Falkai, Thomas G. Schulze, Heike Bickeböller, Urs Heilbronner

Publikováno v: BJPsych Open, Vol 8 (2022)

Background Case-only longitudinal studies are common in psychiatry. Further, it is assumed that psychiatric ratings and questionnaire results of healthy controls stay stable over foreseeable time ranges. For cognitive tests, improvements over time ar

Externí odkaz: https://doaj.org/article/c9e25cb4b8a8494b9c355cc8b4b05e41

Medication Adherence in a Cross-Diagnostic Sample of Patients From the Affective-to-Psychotic Spectrum: Results From the PsyCourse Study

Autor: Sophie-Kathrin Kirchner, Michael Lauseker, Kristina Adorjan, Heike Anderson-Schmidt, Ion-George Anghelescu, Bernhardt T. Baune, Monika Budde, Udo Dannlowski, Detlef E. Dietrich, Andreas J. Fallgatter, Peter Falkai, Christian Figge, Katrin Gade, Urs Heilbronner, Lena Hiendl, Georg Juckel, Janos L. Kalman, Farahnaz Klöhn-Saghatolislam, Carsten Konrad, Fabian U. Lang, Mojtaba Oraki Kohshour, Sergi Papiol, Daniela Reich-Erkelenz, Jens Reimer, Eva Z. Reininghaus, Sabrina K. Schaupp, Max Schmauß, Andrea Schmitt, Eva Christina Schulte, Simon Senner, Carsten Spitzer, Thomas Vogl, Jörg Zimmermann, Alkomiet Hasan, Thomas G. Schulze, Fanny Senner

Publikováno v: Frontiers in Psychiatry, Vol 12 (2022)

IntroductionAccording to the World Health Organization, medication adherence is defined as the extent to which a person's behavior corresponds with an agreed recommendation from a healthcare provider. Approximately 50% of patients do not take their m

Externí odkaz: https://doaj.org/article/22caf5d75c194604ade225abb3ec8dcf

Genetic Overlap Between Alzheimer’s Disease and Bipolar Disorder Implicates the MARK2 and VAC14 Genes

Autor: Ole Kristian Drange, Olav Bjerkehagen Smeland, Alexey A. Shadrin, Per Ivar Finseth, Aree Witoelar, Oleksandr Frei, Psychiatric Genomics Consortium Bipolar Disorder Working Group, Yunpeng Wang, Sahar Hassani, Srdjan Djurovic, Anders M. Dale, Ole A. Andreassen, Eli A Stahl, Gerome Breen, Andreas J Forstner, Andrew McQuillin, Stephan Ripke, Vassily Trubetskoy, Manuel Mattheisen, Jonathan R I Coleman, Heìleìna A Gaspar, Christiaan A de Leeuw, Stacy Steinberg, Jennifer M Whitehead Pavlides, Maciej Trzaskowski, Tune H Pers, Peter A Holmans, Liam Abbott, Esben Agerbo, Huda Akil, Diego Albani, Ney Alliey-Rodriguez, Thomas D Als, Adebayo Anjorin, Verneri Antilla, Swapnil Awasthi, Judith A Badner, Marie Bækvad-Hansen, Jack D Barchas, Nicholas Bass, Michael Bauer, Richard Belliveau, Sarah E Bergen, Carsten Bøcker Pedersen, Erlend Bøen, Marco Boks, James Boocock, Monika Budde, William Bunney, Margit Burmeister, Jonas Bybjerg-Grauholm, William Byerley, Miquel Casas, Felecia Cerrato, Pablo Cervantes, Kimberly Chambert, Alexander W Charney, Danfeng Chen, Claire Churchhouse, Toni-Kim Clarke, William Coryell, David W Craig, Cristiana Cruceanu, David Curtis, Piotr M Czerski, Anders M Dale, Simone de Jong, Franziska Degenhardt, Jurgen Del-Favero, J Raymond DePaulo, Amanda L Dobbyn, Ashley Dumont, Torbjørn Elvsåshagen, Valentina Escott-Price, Chun Chieh Fan, Sascha B Fischer, Matthew Flickinger, Tatiana M Foroud, Liz Forty, Josef Frank, Christine Fraser, Nelson B Freimer, Louise Friseìn, Katrin Gade, Diane Gage, Julie Garnham, Claudia Giambartolomei, Marianne Giørtz Pedersen, Jaqueline Goldstein, Scott D Gordon, Katherine Gordon-Smith, Elaine K Green, Melissa J Green, Tiffany A Greenwood, Jakob Grove, Weihua Guan, Joseì Guzman Parra, Marian L Hamshere, Martin Hautzinger, Urs Heilbronner, Stefan Herms, Maria Hipolito, Per Hoffmann, Dominic Holland, Laura Huckins, Steìphane Jamain, Jessica S Johnson, Anders Jureìus, Radhika Kandaswamy, Robert Karlsson, James L Kennedy, Sarah Kittel-Schneider, Sarah V Knott, James A Knowles, Manolis Kogevinas, Anna C Koller, Ralph Kupka, Catharina Lavebratt, Jacob Lawrence, William B Lawson, Markus Leber, Phil H Lee, Shawn E Levy, Jun Z Li, Chunyu Liu, Susanne Lucae, Anna Maaser, Donald J MacIntyre, Pamela B Mahon, Wolfgang Maier, Lina Martinsson, Steve McCarroll, Peter McGuffin, Melvin G McInnis, James D McKay, Helena Medeiros, Sarah E Medland, Fan Meng, Lili Milani, Grant W Montgomery, Derek W Morris, Thomas W Mühleisen, Niamh Mullins, Hoang Nguyen, Caroline M Nievergelt, Annelie Nordin Adolfsson, Evaristus A Nwulia, Claire O’Donovan, Loes M Olde Loohuis, Anil P S Ori, Lilijana Oruc, Urban Ösby, Roy H Perlis, Amy Perry, Andrea Pfennig, James B Potash, Shaun M Purcell, Eline J Regeer, Andreas Reif, Ceìline S Reinbold, John P Rice, Fabio Rivas, Margarita Rivera, Panos Roussos, Douglas M Ruderfer, Euijung Ryu, Cristina Saìnchez-Mora, Alan F Schatzberg, William A Scheftner, Nicholas J Schork, Cynthia Shannon Weickert, Tatyana Shehktman, Paul D Shilling, Engilbert Sigurdsson, Claire Slaney, Olav B Smeland, Janet L Sobell, Christine Søholm Hansen, Anne T Spijker, David St Clair, Michael Steffens, John S Strauss, Fabian Streit, Jana Strohmaier, Szabolcs Szelinger, Robert C Thompson, Thorgeir E Thorgeirsson, Jens Treutlein, Helmut Vedder, Weiqing Wang, Stanley J Watson, Thomas W Weickert, Stephanie H Witt, Simon Xi, Wei Xu, Allan H Young, Peter Zandi, Peng Zhang, Sebastian Zollner, Rolf Adolfsson, Ingrid Agartz, Martin Alda, Lena Backlund, Bernhard T Baune, Frank Bellivier, Wade H Berrettini, Joanna M Biernacka, Douglas H R Blackwood, Michael Boehnke, Anders D Børglum, Aiden Corvin, Nicholas Craddock, Mark J Daly, Udo Dannlowski, ToÞnu Esko, Bruno Etain, Mark Frye, Janice M Fullerton, Elliot S Gershon, Michael Gill, Fernando Goes, Maria Grigoroiu-Serbanescu, Joanna Hauser, David M Hougaard, Christina M Hultman, Ian Jones, Lisa A Jones, Reneì S Kahn, George Kirov, Mikael Landeìn, Marion Leboyer, Cathryn M Lewis, Qingqin S Li, Jolanta Lissowska, Nicholas G Martin, Fermin Mayoral, Susan L McElroy, Andrew M McIntosh, Francis J McMahon, Ingrid Melle, Andres Metspalu, Philip B Mitchell, Gunnar Morken, Ole Mors, Preben Bo Mortensen, Bertram Müller-Myhsok, Richard M Myers, Benjamin M Neale, Vishwajit Nimgaonkar, Merete Nordentoft, Markus M Nöthen, Michael C O’Donovan, Ketil J Oedegaard, Michael J Owen, Sara A Paciga, Carlos Pato, Michele T Pato, Danielle Posthuma, Josep Antoni Ramos-Quiroga, Marta Ribaseìs, Marcella Rietschel, Guy A Rouleau, Martin Schalling, Peter R Schofield, Thomas G Schulze, Alessandro Serretti, Jordan W Smoller, Hreinn Stefansson, Kari Stefansson, Eystein Stordal, Patrick F Sullivan, Gustavo Turecki, Arne E Vaaler, Eduard Vieta, John B Vincent, Thomas Werge, John I Nurnberger, Naomi R Wray, Arianna Di Florio, Howard J Edenberg, Sven Cichon, Roel A Ophoff, Laura J Scott, Ole A Andreassen, John Kelsoe, Pamela Sklar

Publikováno v: Frontiers in Neuroscience, Vol 13 (2019)

Background: Alzheimer’s disease (AD) and bipolar disorder (BIP) are complex traits influenced by numerous common genetic variants, most of which remain to be detected. Clinical and epidemiological evidence suggest that AD and BIP are related. Howev

Externí odkaz: https://doaj.org/article/86fd88785b5745c79b1fba01a8b863d5

Lipid alteration signature in the blood plasma of individuals with schizophrenia, depression, and bipolar disorder

Autor: Anna Tkachev, Elena Stekolshchikova, Anna Vanyushkina, Hanping Zhang, Anna Morozova, Svetlana Zozulya, Ilia Kurochkin, Nickolay Anikanov, Alina Egorova, Ekaterina Yushina, Thomas Vogl, Fanny Senner, Sabrina K. Schaupp, Daniela Reich-Erkelenz, Sergi Papiol, Mojtaba Oraki Kohshour, Farahnaz Klöhn-Saghatolislam, Janos L. Kalman, Urs Heilbronner, Maria Heilbronner, Katrin Gade, Ashley L. Comes, Monika Budde, Heike Anderson-Schmidt, Kristina Adorjan, Jens Wiltfang, Eva Z. Reininghaus, Georg Juckel, Udo Dannlowski, Andreas Fallgatter, Carsten Spitzer, Max Schmauß, Martin von Hagen, Yana Zorkina, Alexander Reznik, Aleksandra Barkhatova, Roman Lisov, Nikita Mokrov, Maxim Panov, Dmitri Zubkov, Daria Petrova, Chanjuan Zhou, Yiyun Liu, Juncai Pu, Peter Falkai, Georgiy Kostyuk, Tatiana Klyushnik, Thomas G. Schulze, Peng Xie, Eva C. Schulte, Philipp Khaitovich

Publikováno v: JAMA psychiatry 80(3), 250-259 (2023). doi:10.1001/jamapsychiatry.2022.4350

ImportanceNo clinically applicable diagnostic test exists for severe mental disorders. Lipids harbor potential as disease markers.ObjectiveTo define a reproducible profile of lipid alterations in the blood plasma of patients with schizophrenia (SCZ)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::332cc8eddc2e99cbe027290b9b0227e7
https://opus.bibliothek.uni-augsburg.de/opus4/frontdoor/index/index/docId/103305