Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Katriina Kahlos"'
Autor:
Markku Pentikäinen, Piia Simonen, Pauliina Leskelä, Terttu Harju, Pertti Jääskeläinen, Christina Wennerström, Nikolaj Bødker, Eija Heikkilä, Mari Lahelma, Riikka-Leena Leskelä, Airi Puhakka, Elina Heliövaara, Katriina Kahlos, Pentti Korhonen, Tiina Kyllönen, Kirsi Majamaa-Voltti, Anu Turpeinen, Helena Tuunanen, Ville Vepsäläinen, Tapani Vihinen
Publikováno v:
International Journal of Cardiology: Heart & Vasculature, Vol 55, Iss , Pp 101534- (2024)
Objectives: Given that pulmonary arterial hypertension (PAH) and chronic thromboembolic hypertension (CTEPH) are rare yet severe subtypes of pulmonary hypertension significantly impacting patients’ lives, this study analyzed the total societal cost
Externí odkaz:
https://doaj.org/article/945a91e5208a430b8457e6b71529289f
Autor:
Jukka, Sauranen, Anna, Salmela, Katriina, Kahlos, Jaakko, Antonen, Agneta, Ekstrand, Tom, Pettersson
Publikováno v:
Duodecim; laaketieteellinen aikakauskirja. 132(16)
Prevention of organ damage and maintenance of long-term remission are the principal goals for treatment of ANCA-associated vasculitides. This can be accomplished by early diagnosis and swift initiation of remission-inducing agents. Outcome has improv
Publikováno v:
Molecular and Cellular Biochemistry. 254:47-54
We previously reported that exposure to exogenous nitric oxide (NO) causes diminished expression of thioredoxin/thioredoxin reductase, a critical component of the redox system that regulates the functions of redox-sensitive enzymes, receptors, and tr
Publikováno v:
Human Pathology. 33:748-755
Mesothelioma is a fatal tumor resistant to all treatment modalities for reasons that are still unresolved. Glutathione (GSH)-associated pathways are induced by oxidants and cytotoxic drugs, and they are also involved in the progression and resistance
Autor:
Katriina Kahlos, Ylermi Soini, Marjaana Säily, Airi Puhakka, Vuokko L. Kinnula, Paavo Pääkkö, Kaija Linnainmaa, Pirjo Koistinen, Tiina Ollikainen
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 514:7-17
We investigated the role of glutathione and nitric oxide synthase (NOS) in fiber-induced cell and DNA toxicity using alkaline (pH 13) single-cell gel electrophoresis (the Comet assay). Transformed cultured human pleural mesothelial (MeT-5A) cells and
Autor:
Olli, Säynäjäkangas, Ulpu, Tervashonka, Annika, Olli, Merja, Kurkinen, Airi, Jartti, Katri, Vuopala, Katriina, Kahlos
Publikováno v:
Duodecim; laaketieteellinen aikakauskirja. 130(16)
Hepatopulmonary syndrome (HPS) is characterized by the triad of liver disease, intrapulmonary vascular dilatation and arterial deoxygenation. Mediating factors are tumor necrosis factor a, endothelin 1 and nitric oxide. Typical symptom is an increase
Publikováno v:
Duodecim; laaketieteellinen aikakauskirja. 130(9)
Acute or subactute pulmonary damage can be either idiopathic or resulting from a known cause. The most common histologic types are diffuse acute alveolar damage (DAD) and organizing pneumonia (OP). Various kinds of infection, pulmonary drug reactions
Autor:
Vuokko L. Kinnula, Paavo Pääkkö, Kaija Linnainmaa, Ylermi Soini, Raija Sormunen, Katriina Kahlos, Riitta Kaarteenaho-Wiik
Publikováno v:
Cancer. 91:1349-1357
BACKGROUND Free radicals and antioxidant enzymes (AOEs) may play a critical role in cell proliferation and in the resistance of malignant cells against cytotoxic drugs and radiation. Malignant mesothelioma is a resistant tumor with high levels of man
Autor:
Pirjo Koistinen, Paavo Pääkkö, Vuokko L. Kinnula, Sakari Kakko, Katriina Kahlos, Arne Holmgren, Ylermi Soini, Marjaana Säily
Publikováno v:
International Journal of Cancer. 95:198-204
Thioredoxin (Trx) with a redoxactive dithiol together with NADPH and thioredoxin reductase (TrxR) is a major disulfide reductase regulating cellular redox state and cell proliferation and possibly contributing to the drug resistance of malignant cell
Publikováno v:
British Journal of Cancer
Although several immunohistochemical markers are available, differential diagnosis between mesothelioma and metastatic adenocarcinoma of the pleura is difficult. We have found that the immunoreactivity of manganese superoxide dismutase (MnSOD), an im