Výsledky vyhledávání - "Katrien Smaers"

The Flavonoid Luteolin Increases the Resistance of Normal, but Not Malignant Keratinocytes, Against UVB-Induced Apoptosis

Autor: Katrien Smaers, Charlotte M. Proby, Daniel H. Maes, Sofie Van Kelst, Lien Verschooten, Marjan Garmyn, Patrizia Agostinis, Lieve Declercq

Publikováno v: Journal of Investigative Dermatology. 130:2277-2285

Adequate protection of skin against the carcinogenic effects of UVB irradiation is essential. Flavonoids may have a conspicuous role in cancer prevention because of their antioxidant, anti-inflammatory, and growth-inhibitory effects. Therefore, we te

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d462971b58e0d328cf9f00ccb3a25858
https://doi.org/10.1038/jid.2010.124

Zobrazit plný text záznamu

A Low UVB Dose, with the Potential to Trigger a Protective p53-Dependent Gene Program, Increases the Resilience of Keratinocytes against Future UVB Insults

Autor: Daniel H. Maes, Liesbeth Declercq, M. Garmyn, David Decraene, Mary Matsui, Katrien Smaers

Publikováno v: Journal of Investigative Dermatology. (5):1026-1031

One protein central in the response of human keratinocytes to ultraviolet B damage is p53. By transactivating genes involved in either cell cycle arrest or DNA repair, p53 has a leading role in the recovery from this damage. Considering this role, we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de32478692a5f286b8a9b10b4e9da0eb

Zobrazit plný text záznamu

A Synthetic Superoxide Dismutase/Catalase Mimetic (EUK-134) Inhibits Membrane-Damage-Induced Activation of Mitogen-Activated Protein Kinase Pathways and Reduces p53 Accumulation in Ultraviolet B-Exposed Primary Human Keratinocytes

Autor: Mary Matsui, T. Mammone, Katrien Smaers, David Decraene, David C. Gan, Lieve Declercq, Daniel H. Maes, Marjan Garmyn

Publikováno v: Journal of Investigative Dermatology. (2):484-491

Salen-manganese complexes exhibit powerful superoxide dismutase and catalase activity, with pharmacologic efficacy in several oxidative-stress-associated disease models. Ultraviolet (UV) B not only induces direct DNA damage, but also generates oxidat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::907741fc5fdfac6bce94616d12a25d27

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání