Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Katrien Cludts"'
Autor:
Matthias M. Engelen, Quentin Van Thillo, Albrecht Betrains, Iwein Gyselinck, Caroline P. Martens, Valérie Spalart, Anna Ockerman, Caroline Devooght, Joost Wauters, Jan Gunst, Carine Wouters, Christophe Vandenbriele, Steffen Rex, Laurens Liesenborghs, Alexander Wilmer, Philippe Meersseman, Greet Van den Berghe, Dieter Dauwe, Ann Belmans, Michiel Thomeer, Tom Fivez, Dieter Mesotten, David Ruttens, Luc Heytens, Ilse Dapper, Sebastiaan Tuyls, Brecht De Tavernier, Peter Verhamme, Thomas Vanassche, Eric Van Wijngaerden, Wim Janssens, Geert Meyfroidt, Robin Vos, Timothy Devos, Paul De Munter, Johan Neyts, Lieven Dupont, Isabel Spriet, Geert Verbeke, Kathleen Claes, Wim Robberecht, Chris Van Geet, Barbara Debaveye, Helga Ceunen, Veerle Servaes, Katrien Cludts, Kristine Vanheule, Cato Jacobs, Daimy Roebroek, Paulien Dreesen, Nele Smet, Jan Dolhain, Mieke Hoppenbrouwers, Kathleen Wens, Kristel Daems, Monique D’hondt
Background Thromboinflammation plays a central role in severe COVID-19. The kallikrein pathway activates both inflammatory pathways and contact-mediated coagulation. We investigated if modulation of the thromboinflammatory response improves outcomes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75c5f41c448b70de604ebd3b2b4bbd89
http://hdl.handle.net/1942/38953
http://hdl.handle.net/1942/38953
Autor:
Marc Hoylaerts, Marleen Lox, Laurens Liesenborghs, Thomas Vanassche, Christophe Vandenbriele, Elizabeth A. V. Jones, Maarten Criel, Peter Verhamme, Katrien Cludts, Soetkin Van kerckhoven, Benedetta Izzi
Publikováno v:
Thrombosis Research, 146, 76-83. Elsevier Science
Background Platelet Endothelial Aggregation Receptor-1 (PEAR1) is a transmembrane platelet receptor that amplifies the activation of the platelet fibrinogen receptor (αIIbβ3) during platelet aggregation. In man, Pear1 polymorphisms are associated w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17807d10dc9577782487e704d1576e8c
https://doi.org/10.1016/j.thromres.2016.08.026
https://doi.org/10.1016/j.thromres.2016.08.026
Autor:
Katrien Cludts, Benedetta Izzi, Diether Lambrechts, Mariaelena Pistoni, Pinar Akkor, Peter Verhamme, Catherine M. Verfaillie, Marc Hoylaerts, Kathleen Freson
Publikováno v:
Blood. 128:1003-1012
Genetic variation in the PEAR1 locus is linked to platelet reactivity and cardiovascular disease. The major G allele of rs12041331, an intronic cytosine guanine dinucleotide-single-nucleotide polymorphism (CpG-SNP), is associated with higher PEAR1 ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15eee14a568913b8ef1d24e396ae2dcc
https://doi.org/10.1182/blood-2015-11-682153
https://doi.org/10.1182/blood-2015-11-682153
Cell-Specific PEAR1 Methylation Studies Reveal a Locus that Coordinates Expression of Multiple Genes
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 4, p 1069 (2018)
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 19; Issue 4; Pages: 1069
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 19; Issue 4; Pages: 1069
Chromosomal interactions connect distant enhancers and promoters on the same chromosome, activating or repressing gene expression. PEAR1 encodes the Platelet-Endothelial Aggregation Receptor 1, a contact receptor involved in platelet function and meg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c66c7c757d2bc37455cbceda4b2f8ef
http://www.mdpi.com/1422-0067/19/4/1069
http://www.mdpi.com/1422-0067/19/4/1069
Autor:
C Long, Marc Jacquemin, Katrien Cludts, Jan Emmerechts, Serena Loyen, I Van Linthout, Marc Hoylaerts, Alexandre Kauskot, Thomas Vanassche, Peter Verhamme
Publikováno v:
Thrombosis Research. 129:514-519
Introduction Partial inhibition of Factor VIII (FVIII) may provide antithrombotic efficacy whilst avoiding excessive anticoagulation. Materials and Methods We studied the anticoagulant effects of a partial (TB-402) and a complete (BO2C11) FVIII-inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b913586d596eef0525c761a4eee5dccb
https://doi.org/10.1016/j.thromres.2011.06.027
https://doi.org/10.1016/j.thromres.2011.06.027
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 27:2163-2169
Objective— Thrombospondin-1 (TSP1) is described as a positive regulator of vascular smooth muscle growth in cell culture. However, insight into the in vivo effects of TSP1 on smooth muscle cell (SMC) function is lacking. Methods and Results— We a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f2fe12b389d72755ff153f893f57d66
https://doi.org/10.1161/atvbaha.107.151282
https://doi.org/10.1161/atvbaha.107.151282
Autor:
Katrien Cludts, Maarten Criel, Yiting Sun, Peter Verhamme, Soetkin Van kerckhoven, Thomas Vanassche, Marc Hoylaerts, Christophe Vandenbriele, Benedetta Izzi
Dextran sulfate (DxS; Mr 500 kD) induces fibrinogen receptor (αIIbβ3) activation via CLEC-2/Syk signaling and via a Syk-independent SFK/PI3K/Akt-dependent tyrosine kinase pathway in human and murine platelets. The platelet surface receptor, respons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2813325a8e557b972465619293057f47
Publikováno v:
Lipids in Health and Disease
Lipids in Health and Disease, Vol 10, Iss 1, p 41 (2011)
Lipids in Health and Disease, Vol 10, Iss 1, p 41 (2011)
Background In this study we investigated the antiatherogenic effect of dietary enrichment of a combination of extra virgin olive oil (EVO) and seal oil on apolipoprotein E-deficient (apoE-/-). Methods Six-week-old female and male apoE-/- mice were fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1685ed70fbf9a764c9a2e822c8b75a62
https://hdl.handle.net/10037/3303
https://hdl.handle.net/10037/3303