Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Katri Sofjan"'
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Most CAR designs lack control and computation features, limiting the sophistication of the engineered immune response. Here the authors leverage a split CAR design for engineering coordinated immune responses.
Externí odkaz:
https://doaj.org/article/61f573b3bec2461cb3c23455806f7d6a
Autor:
Karrie Wong, Sharon Lin, Christopher Wrocklage, Katri Sofjan, Leila Williams, Mallory Brady, Nicholas Colletti, Noah Tubo, Hugh Gannon, Robert LaMothe, Tianlei Xu, Tracy VandenBerg, Sol Shenker, Caroline Dugopolski, Frank Stegmeier, Louise Cadzow, Michael Schlabach, Micah Benson
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/490a3e91b10d4fd1b0d7fff1fe4208ff
Autor:
Sharon Lin, Leila Williams, Mitali Ghose, Hugh Gannon, Conor Calnan, Angelina Pizzo, Pei-Lun Kao, Mallory Brady, Katri Sofjan, Anne Dodson, Sol Shenker, Michael Schlabach, Fiona Sharp, Frank Stegmeier, Micah Benson, Karrie Wong
Publikováno v:
Regular and Young Investigator Award Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82c507cbbaec94af8cd61117bc10704a
https://doi.org/10.1136/jitc-2022-sitc2022.0255
https://doi.org/10.1136/jitc-2022-sitc2022.0255
Autor:
Karl P. Gerhardt, Ravi U. Sheth, Felix Ekness, Brian P. Landry, Kathryn R. Brink, Kristina N.-M. Daeffler, Nikola Dyulgyarov, Katri Sofjan, Sebastian R. Schmidl, Jeffrey J. Tabor
Publikováno v:
Nature Chemical Biology. 15:690-698
Two-component systems (TCSs) are the largest family of multi-step signal transduction pathways and valuable sensors for synthetic biology. However, most TCSs remain uncharacterized or difficult to harness for applications. Major challenges are that m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9c59772d2104161242e2bf72ff65ee6
https://doi.org/10.1038/s41589-019-0286-6
https://doi.org/10.1038/s41589-019-0286-6
Autor:
Katri Sofjan, Sharon Lin, Sol Shenker, Caroline Dugopolski, Leila Williams, Karrie Wong, Christopher Wrocklage, Mallory Brady, Hugh S. Gannon, Frank Stegmeier, Robert A. LaMothe, Tracy VandenBerg, Noah Tubo, Micah J. Benson, Tianlei Xu, Nicholas John Colletti, Michael R. Schlabach, Louise Cadzow
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundAdoptive cell therapy with ex vivo expanded tumor infiltrating lymphocytes (TIL) offers a potentially curative treatment for cancer. However, the immunosuppressive tumor microenvironment limits the effectiveness of TIL therapy. To address t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::371108ad5027546da9bc87379ceea304
https://doi.org/10.1136/jitc-2021-sitc2021.186
https://doi.org/10.1136/jitc-2021-sitc2021.186
Autor:
Conor Calnan, Michael R. Schlabach, Sharon Lin, Louise Cadzow, Sol Shenker, Frank Stegmeier, Katri Sofjan, Karrie Wong, Isabelle Le Mercier, Anja Hohmann, Gregory Kryukov, Micah J. Benson, Christopher Wrocklage, Leila Williams, Caroline Bullock
Publikováno v:
Journal for ImmunoTherapy of Cancer. 9:A215-A215
BackgroundThe application of CRISPR/Cas9-gene-editing to enhance the anti-tumor activity of T cell Adoptive Cell Therapies (ACT) is a promising approach in the treatment of patients with solid tumors. We developed an in vivo CRISPR^2 screening approa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3301c947a585778b94ed2540c6c9ce34
https://doi.org/10.1136/jitc-2021-sitc2021.204
https://doi.org/10.1136/jitc-2021-sitc2021.204