Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Katleen Broos"'
Autor:
Ranhua Xiong, Roosmarijn E. Vandenbroucke, Katleen Broos, Toon Brans, Elien Van Wonterghem, Claude Libert, Jo Demeester, Stefaan C. De Smedt, Kevin Braeckmans
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
Measuring the size distribution of nanomaterials in biological fluids is crucial to understand their properties in vivo. Here, the authors apply fluorescence recovery after photobleaching to measure protein aggregation in serum and to study permeabil
Externí odkaz:
https://doaj.org/article/4489899247274c518a87bcf6d594dca1
Autor:
Elien Vermeersch, Benedicte P. Nuyttens, Claudia Tersteeg, Katleen Broos, Simon F. De Meyer, Karen Vanhoorelbeke, Hans Deckmyn
Publikováno v:
TH Open, Vol 02, Iss 03, Pp e272-e279 (2018)
Despite the absence of the genome in platelets, transcription profiling provides important insights into platelet function and can help clarify abnormalities in platelet disorders. The Bloodomics Consortium performed whole-genome expression analysis
Externí odkaz:
https://doaj.org/article/ee718168a00f4b22952fd10dc5672597
Autor:
Tim Thijs, Katleen Broos, Stefaan J Soenen, Aline Vandenbulcke, Karen Vanhoorelbeke, Hans Deckmyn, Isabelle I Salles-Crawley
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132899 (2015)
In recent years, candidate genes and proteins implicated in platelet function have been identified by various genomic approaches. To elucidate their exact role, we aimed to develop a method to apply miRNA interference in platelet progenitor cells by
Externí odkaz:
https://doaj.org/article/169a802e306b4e46b8a038eac71fea81
Autor:
Sandra Van Lint, Stephanie Du Four, Véronique Flamand, Karine Breckpot, Kevin Van der Jeught, Lukasz Bialkowski, Cleo Goyvaerts, Sarah Maenhout, Lode Goethals, Daphné Benteyn, Dries Renmans, Kris Thielemans, Katleen Broos, Carlo Heirman
Publikováno v:
Cancer Immunology Research. 4:146-156
Modulating the activity of tumor-infiltrating dendritic cells (TiDC) provides opportunities for novel cancer interventions. In this article, we report on our study of the uptake of mRNA by CD8α+ cross-presenting TiDCs upon its intratumoral (i.t.) de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c8de96820499e3ebc8d6f153a204838
https://doi.org/10.1158/2326-6066.cir-15-0163
https://doi.org/10.1158/2326-6066.cir-15-0163
Autor:
Claude Libert, Ranhua Xiong, Roosmarijn E. Vandenbroucke, Toon Brans, Katleen Broos, Elien Van Wonterghem, Kevin Braeckmans, Jo Demeester, Stefaan C. De Smedt
Publikováno v:
NATURE COMMUNICATIONS
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
Sizing nanomaterials in complex biological fluids, such as blood, remains a great challenge in spite of its importance for a wide range of biomedical applications. In drug delivery, for instance, it is essential that aggregation of protein-based drug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::138fcf00943fb928adf1dd2b338432df
https://hdl.handle.net/1854/LU-8167381
https://hdl.handle.net/1854/LU-8167381
Publikováno v:
Thrombosis Research. 127:S26-S29
Platelets play a central role in maintaining hemostasis mainly by binding to subendothelial collagen exposed upon vascular injury, thereby initiating thrombus formation. Platelets can bind directly to the exposed collagen through two major receptors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec2b9e6c0897026e6ee5bb10f21f1b6b
https://doi.org/10.1016/s0049-3848(10)70151-1
https://doi.org/10.1016/s0049-3848(10)70151-1
Autor:
Karen Vanhoorelbeke, Hans Deckmyn, Isabelle I. Salles, Alexandre Fontayne, Tímea Szántó, Changgeng Ruan, Katleen Broos, Alan T. Nurden
Publikováno v:
Thrombosis and Haemostasis. 104:392-401
SummaryPlatelets play an essential role in the development of cardiovascular diseases and are the target of several agents that can inhibit their function. Despite the existence of a wide array of techniques to study platelet function, an assay to ev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d3fae689ba8959e26e64afe45385429
https://doi.org/10.1160/th09-07-0505
https://doi.org/10.1160/th09-07-0505
Autor:
Tiny Deschrijver, Hans Deckmyn, Peter Verwilst, Wim Dehaen, Wim M. De Borggraeve, Katleen Broos
Publikováno v:
Tetrahedron. 65:4521-4529
A library of 1,4-benzodiazepin-3-one-based turn mimetics were synthesized and tested for their antithrombotic abilities. These mimetics are designed to incorporate amino acid side chains of the previously reported paratope of the inhibitory anti-von
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec8da3eef69f2f4359ccc0118b528947
https://doi.org/10.1016/j.tet.2009.03.095
https://doi.org/10.1016/j.tet.2009.03.095
Autor:
Katleen Broos, Marc Coosemans, Karin De Ridder, Patrick De Baetselier, Jeremy M Sternberg, Ine De Goeyse, Yves Guisez, Guy Caljon, Jan Van Den Abbeele
Publikováno v:
Insect biochemistry and molecular biology
Our previous screening of a Glossina morsitans morsitans λgt11 salivary gland expression library with serum of a tsetse fly exposed rabbit identified a cDNA encoding Tsetse Antigen5 (TAg5, 28.9 kDa), a homologue of Antigen5 sting venom allergens. Re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bd1f1bcb77ad70d3ca77d0679d67f69
https://doi.org/10.1016/j.ibmb.2009.01.010
https://doi.org/10.1016/j.ibmb.2009.01.010
Publikováno v:
British Journal of Haematology. 142:515-528
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2f328d40dee28dd201d6f0960360d32
https://doi.org/10.1111/j.1365-2141.2008.07233.x
https://doi.org/10.1111/j.1365-2141.2008.07233.x