Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Katjana Schwab"'
Autor:
Katjana Schwab, Konstantin Riege, Luis Coronel, Clara Stanko, Silke Förste, Steve Hoffmann, Martin Fischer
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-8 (2024)
Abstract The transcription factor regulatory factor X 7 (RFX7) has been identified as a tumor suppressor that is recurrently mutated in lymphoid cancers and appears to be dysregulated in many other cancers. RFX7 is activated by the well-known tumor s
Externí odkaz:
https://doaj.org/article/e534e98200654b9791d782f12a46e429
Autor:
Michael Serries, Hannah Zenzen, Mario Heine, Tobias Holderried, Peter Brossart, Katjana Schwab
Publikováno v:
Hematology, Vol 28, Iss 1 (2023)
ABSTRACTIntroduction: There are conflicting results concerning the outcome of patients after an allogeneic hematopoietic stem cell transplantation (allo-HSCT) who required treatment in the intensive care unit (ICU). The aim of this study was to evalu
Externí odkaz:
https://doaj.org/article/dc23a2cd9ec04c569793685941cee04f
Autor:
Claudio Neidhöfer, Esther Sib, Marcel Neuenhoff, Oliver Schwengers, Tobias Dummin, Christian Buechler, Niklas Klein, Julian Balks, Katharina Axtmann, Katjana Schwab, Tobias A. W. Holderried, Georg Feldmann, Peter Brossart, Steffen Engelhart, Nico T. Mutters, Gabriele Bierbaum, Marijo Parčina
Publikováno v:
Antimicrobial Resistance and Infection Control, Vol 12, Iss 1, Pp 1-17 (2023)
Abstract Background Hospitals with their high antimicrobial selection pressure represent the presumably most important reservoir of multidrug-resistant human pathogens. Antibiotics administered in the course of treatment are excreted and discharged i
Externí odkaz:
https://doaj.org/article/f55e9aef5f514f97ad547deec3ed7ce5
Autor:
Katjana Schwab, Luis Coronel, Konstantin Riege, Erika K. Sacramento, Norman Rahnis, David Häckes, Emilio Cirri, Marco Groth, Steve Hoffmann, Martin Fischer
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-9 (2023)
Abstract Recurrently mutated in lymphoid neoplasms, the transcription factor RFX7 is emerging as a tumor suppressor. Previous reports suggested that RFX7 may also have a role in neurological and metabolic disorders. We recently reported that RFX7 res
Externí odkaz:
https://doaj.org/article/49b81b484eb94360a680e1b62c99d075
Autor:
Annette Böhmer, Saskia Barz, Katjana Schwab, Ulrike Kolbe, Anke Gabel, Joanna Kirkpatrick, Oliver Ohlenschläger, Matthias Görlach, Frank-D. Böhmer
Publikováno v:
Redox Biology, Vol 28, Iss , Pp - (2020)
Oxidative modification of cysteine residues has been shown to regulate the activity of several protein-tyrosine kinases. We explored the possibility that Fms-like tyrosine kinase 3 (FLT3), a hematopoietic receptor-tyrosine kinase, is subject to this
Externí odkaz:
https://doaj.org/article/733061e6529849cea6b72e1d9892b97e
Autor:
Elina Wiechens, Flavia Vigliotti, Konstantin Riege, Alena van Bömmel, Katjana Schwab, Ivonne Görlich, Martin Bens, Robert Schwarz, Arne Sahm, Marco Groth, Alexander Loewer, Steve Hoffmann, Martin Fischer
The coordination of transcription through enhancers and promoters is a fundamental process that has a central role in development and disease 1–3. Convergent transcription, i.e., the collision of sense and antisense transcription, is ubiquitous in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6d3b3396fd4a11fd6948f20a304b513
https://doi.org/10.21203/rs.3.rs-2803901/v1
https://doi.org/10.21203/rs.3.rs-2803901/v1
Autor:
Katjana Schwab, Luis Coronel, Konstantin Riege, Erika K. Sacramento, Norman Rahnis, David Häckes, Emilio Cirri, Marco Groth, Steve Hoffmann, Martin Fischer
Recurrently mutated in lymphoid neoplasms, the transcription factor RFX7 is emerging as a tumor suppressor. Previous reports suggested that RFX7 may also have a role in neurological and metabolic disorders. We recently reported that RFX7 responds to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6d0078a83c5e50a718a77a5c215ab6e
https://doi.org/10.1101/2022.12.05.519097
https://doi.org/10.1101/2022.12.05.519097
Publikováno v:
Oncogene. 41(7)
In recent years the tumor suppressor p53 has been increasingly recognized as a potent regulator of the cell metabolism and for its ability to inhibit the critical pro-survival kinases AKT and mTOR. The mechanisms through which p53 controls AKT and mT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::226bd5b79ee38fcfa9bdf0a534ecd1f6
https://pubmed.ncbi.nlm.nih.gov/34907345
https://pubmed.ncbi.nlm.nih.gov/34907345
Autor:
Steve Hoffmann, Stephan H. Bernhart, Luis Coronel, Reiner Siebert, Martin Fischer, Silke Förste, Lena Semerau, David Häckes, Katjana Schwab, Konstantin Riege
Publikováno v:
Nucleic Acids Research
Nucleic acids research, 49(13):7437-7456
Nucleic acids research, 49(13):7437-7456
Despite its prominence, the mechanisms through which the tumor suppressor p53 regulates most genes remain unclear. Recently, the regulatory factor X 7 (RFX7) emerged as a suppressor of lymphoid neoplasms, but its regulation and target genes mediating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c23ccaea6fe28945d0112e62d31e221
https://doi.org/10.1101/2021.03.25.436917
https://doi.org/10.1101/2021.03.25.436917
Autor:
Kathrin Nachtkamp, Mathias Haenel, Sonja Martin, Julia Marx, Georg Lenz, Wolfgang E. Berdel, Matthias Stelljes, Nael Alakel, Tim Sauer, Simon Raffel, Bernd M. Spriewald, Ralph Wäsch, Nicola Goekbuget, Sebastian Scholl, Katjana Schwab, Martin Dugas, Andreas Rank, Julian Knaden, Monika Brueggemann, Klaus Wethmar, Maher Hanoun
Publikováno v:
Blood. 138:2300-2300
Introduction: Acute lymphoblastic leukemia (ALL) represents approx. 5% of all newly diagnosed leukemias in patients between 55 and 70 years of age. Despite recent advances especially in younger patients, the prognosis of elderly patients with ALL rem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::880ec0deca96fce202a0b257ac8ae898
https://doi.org/10.1182/blood-2021-145553
https://doi.org/10.1182/blood-2021-145553